Predictive and Prognostic Factors in Long Term Survival of Small Cell Lung Cancer

AYGENCEL BIKMAZ Ş. G., OĞUZÜLGEN İ. K., ÖZTÜRK C.

TURKISH THORACIC JOURNAL, cilt.6, sa.1, ss.81-84, 2005 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 1
  • Basım Tarihi: 2005
  • Dergi Adı: TURKISH THORACIC JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.81-84
  • Anahtar Kelimeler: small cell lung cancer, prognostic factors, long term survival
  • Gazi Üniversitesi Adresli: Evet

Özet

Small cell lung cancer (SCLC) is an extremely aggressive tumour with a poor clinical course. It is however responsive to both chemotherapy and radiotherapy. Some clinical and laboratory parameters can predict response to chemotherapy and long term survival in SCLC. In this study, we presented 3 SCLC patients as long term survivors. We tried to find some prognostic factors that identify long term survivors. We also compared our results with previous studies. We found that performance status, extent of disease and patient's age were the most important clinical factors in long term survival. Also lactate dehydrogenase (LDH) level was the most important pretreatment laboratory parameter. These factors may be used to figure out good or poor prognosis in SCLC patients and to help clinician make appropriate treatment decisions for individuals.