Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions

Ozturk B., Tutuncu E., KUŞCU F., Gurbuz Y., Sencan I., Tuzun H.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, cilt.16, sa.2, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ijid.2011.06.005
  • Dergi Adı: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Crimean-Congo hemorrhagic fever, Prognosis, Fatality, RISK-FACTORS
  • Gazi Üniversitesi Adresli: Hayır

Özet

Background: Crimean-Congo hemorrhagic fever (CCHF) is one of the viral hemorrhagic fevers caused by tick bites. Common symptoms of the infection are fatigue, high fever, headache, and myalgia. In some patients hemorrhage may accompany these symptoms and is a sign of a poor prognosis. Typical laboratory changes are thrombocytopenia, leukopenia, elevation of aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine phosphokinase (CPK), and lactate dehydrogenase (LDH), and prolongation of prothrombin time (PT) and activated partial thromboplastin time (aPTT). Mortality rates vary between 3% and 30%. The aim of this study was to determine the factors affecting the prognosis of CCHF.