Beneficial effect of hyperbaric oxygenation on liver regeneration in cirrhosis

Ozdogan, M; Ersoy, E; Dundar, K; Albayrak, L; Devay, S; Gundogdu, H

doi:10.1016/j.jss.2005.06.036

Beneficial effect of hyperbaric oxygenation on liver regeneration in cirrhosis

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Ozdogan M., Ersoy E., Dundar K., Albayrak L., Devay S., Gundogdu H.

JOURNAL OF SURGICAL RESEARCH, vol.129, no.2, pp.260-264, 2005 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 129 Issue: 2
Publication Date: 2005
Doi Number: 10.1016/j.jss.2005.06.036
Title of Journal : JOURNAL OF SURGICAL RESEARCH
Page Numbers: pp.260-264

Abstract

Background. Underlying hepatic injury and cirrhosis are leading factors that interfere with the postoperative liver regeneration and function. Hyperbaric oxygenation (HBO) has been reported to ameliorate the ischemia-reperfusion injury of the liver, to induce compensatory hypertrophy of the predicted remnant liver in rats after portal vein ligation and to augment liver regeneration after hepatectomy in non-cirrhotic rats. Our aim was to determine the effect of HBO treatment on liver regeneration after partial hepatectomy in normal and cirrhotic mice in this experimental study.