Beneficial effect of hyperbaric oxygenation on liver regeneration in cirrhosis

Ozdogan M., Ersoy E., Dundar K., Albayrak L., Devay S., Gundogdu H.

JOURNAL OF SURGICAL RESEARCH, cilt.129, sa.2, ss.260-264, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 129 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.jss.2005.06.036
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.260-264
  • Gazi Üniversitesi Adresli: Hayır

Özet

Background. Underlying hepatic injury and cirrhosis are leading factors that interfere with the postoperative liver regeneration and function. Hyperbaric oxygenation (HBO) has been reported to ameliorate the ischemia-reperfusion injury of the liver, to induce compensatory hypertrophy of the predicted remnant liver in rats after portal vein ligation and to augment liver regeneration after hepatectomy in non-cirrhotic rats. Our aim was to determine the effect of HBO treatment on liver regeneration after partial hepatectomy in normal and cirrhotic mice in this experimental study.