Evulation of Antimutagenic Activity of Ni(II) Complexes with Unsymmetric Schiff Bases


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Nartop D., Hasanoğlu Özkan E. , Kızıl H. E. , Ağar G., Sarı N.

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, vol.8, pp.608-616, 2020 (National Refreed University Journal)

  • Publication Type: Article / Article
  • Volume: 8
  • Publication Date: 2020
  • Doi Number: 10.29130/dubited.575747
  • Title of Journal : Düzce Üniversitesi Bilim ve Teknoloji Dergisi
  • Page Numbers: pp.608-616

Abstract

In this work, Ni(II) complexes with unsymmetric Schiff bases (NiL1, NiL2, NiL3, NiL4) were prepared by a two-stage method reported by one of us recently for investigate antimutagenic properties. Sodium azide-induced antimutagenic effect in lymphocytes was determined by sister chromatid exchange (SCE) and micronucleus (MN) methods. It has been determined that the synthesized compounds have antimutagenic properties and reduce the mutagenicity caused by sodium azide (NaN3) which is used as a positive control.