Overview of nutritional approach in hematopoietic stem cell trans-plantation: COVID-19 update

AKBULUT G., YEŞİLDEMİR Ö.

WORLD JOURNAL OF STEM CELLS, cilt.13, sa.10, ss.1530, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 13 Sayı: 10
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4252/wjsc.v13.i10.1530
  • Dergi Adı: WORLD JOURNAL OF STEM CELLS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE
  • Sayfa Sayıları: ss.1530
  • Anahtar Kelimeler: COVID-19, Hematopoietic stem cell transplantation, Nutrition, Nutritional approach, NEUTROPENIC DIET, CLINICAL IMPACT, COMPLICATIONS, SUPPORT, GUIDELINES, INFECTION, GLUTAMINE, THERAPY, PILOT, SUPPLEMENTATION
  • Gazi Üniversitesi Adresli: Evet

Özet

The coronavirus disease 2019 (COVID-19) is caused by the newly discovered SARS-CoV-2. Hematopoietic stem cell transplantation (HSCT) is a high-risk procedure. The novelty of COVID-19 has created more uncertainty during all phases of HSCT. It is thought that HSCT patients taking immunosuppressive agents are more likely to contract COVID-19 than healthy individuals are. Appropriate care precautions should be taken with patients undergoing HSCT to minimize the risk of COVID-19, and appropriate treatment methods must be followed in patients infected with COVID-19. Malnutrition has become a significant problem in HSCT patients during the COVID-19 pandemic. The causes of malnutrition in HSCT patients are multifactorial. However, the most important reason is the decrease in energy and nutrient intake. The HSCT procedure can lead to many complications such as dysgeusia, mucositis, diarrhea, constipation, xerostomia and vomiting/nausea. Improving the nutritional status of HSCT patients by managing each of these special complications with an appropriate nutritional approach is essential for successful engraftment. This review aims to provide a comprehensive overview of the specific complications affecting the nutritional status of HSCT patients and their nutritional approach during the challenging COVID-19 pandemic.