Association of serum total bilirubin level with severity of coronary atherosclerosis is linked to systemic inflammation


Akboga M. K. , CANPOLAT U., Sahinarslan A., Alsancak Y., Nurkoc S., Aras D., ...More

ATHEROSCLEROSIS, vol.240, no.1, pp.110-114, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 240 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1016/j.atherosclerosis.2015.02.051
  • Journal Name: ATHEROSCLEROSIS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.110-114
  • Keywords: Bilirubin, Inflammation, CRP, NLR, RDW, Atherosclerosis, LOW-DENSITY-LIPOPROTEIN, CELL DISTRIBUTION WIDTH, C-REACTIVE PROTEIN, LYMPHOCYTE RATIO, ENDOTHELIAL FUNCTION, INVERSE RELATIONSHIP, ARTERY-DISEASE, NEUTROPHIL, METAANALYSIS, RISK

Abstract

Objective: Although cardiovascular protective action of bilirubin has been attributed to its antioxidant effect, there was scarce data regarding the anti-inflammatory properties. Herein, we aimed to assess the relationship between serum total bilirubin level and severity of coronary artery disease (CAD) in association with the direct inflammatory marker such as C-reactive protein (CRP), the other indirect markers included in inflammation process such as neutrophil to lymphocyte ratio (NLR) and red cell distribution width (RDW) in patients with stable CAD.