Possible Genetic Factors Associated with Type 1 Diabetes Mellitus Susceptibility

EROĞLU ALTINOVA A., Yetkin L.

MARMARA MEDICAL JOURNAL, cilt.24, sa.2, ss.126-130, 2011 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 24 Sayı: 2
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5472/mmj.2011.01874.0
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.126-130
  • Anahtar Kelimeler: Type 1 diabetes, Susceptibility, Genetic factors
  • Gazi Üniversitesi Adresli: Evet

Özet

Type 1 diabetes mellitus is a chronic autoimmune disease characterized by immune-mediated destruction of the beta-cells in the pancreas which results from the action of environmental factors on genetically predisposed individuals. The incidence of type 1 diabetes has been increasing worldwide. Its etiology is complex and remains unknown. In this review, possible genetic factors associated with the susceptibility of type 1 diabetes are discussed.