Assessment of Endothelial Dysfunction with Methylated Arginines and L-arginine in Cadmium-Exposed People: a Pilot Study.

Tutkun L., Gunduzoz M., Türksoy V. A., Deniz S., Oztan O., Çetintepe S. P., ...Daha Fazla

Clinical laboratory, cilt.65, sa.10, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 10
  • Basım Tarihi: 2019
  • Doi Numarası: 10.7754/clin.lab.2019.181249
  • Dergi Adı: Clinical laboratory
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: cadmium exposure, atherosclerosis, asymmetric dimethyl arginine (ADMA), endothelial dysfunction, methylated arginines, ASYMMETRIC DIMETHYLARGININE ADMA, RISK-FACTOR, ATHEROSCLEROSIS, MECHANISMS, ZINC, METABOLISM, RATIO, LEAD
  • Gazi Üniversitesi Adresli: Evet

Özet

Background: Workers can be exposed to cadmium (Cd) in various industries. On the other hand, another potential source for Cd exposure is the food chain and smoking. Environmental pollution to Cd plays an important role in the development of atherosclerosis. Asymmetric dimethyl arginine (ADMA) levels promote the development of endothelial dysfunction and atherosclerosis-related diseases such as hypertension, acute coronary syndrome, congestive heart failure, and peripheral vascular diseases. The aim of this study is to evaluate the cardiovascular risks of non-symptomatic cadmium-exposed workers and to promote the value of methylated arginines in screening of toxic exposures.