Institution Of The Thesis: Gazi University, Turkey
Approval Date: 2017
Thesis Language: Turkish
Student: Miray Eryaprak
Consultant: NEBAHAT DEĞİRMENBAŞIAbstract:
In recent years, due to the disadvantages of using molecular bromine in organic synthesis, the importance of using environmentally friendly brominated organic compounds have been increasing. New environmentally friendly methods are being developed for oxidation of alcohols to carbonyl compounds under neutral and mild conditions. In addition, studies on the use of ultrasonic waves in organic reactions have gained importance. In this study, a new bromo-organic compound, 2-methylimidazolium bromochromate (2-MIBC) and alumina supported 2-methylimidazolium bromochromate (2-MIBC/alumina) were synthesized. The structure of 2-MIBC was elucidated. Properties such as melting point, solubility, pH and conductivity were investigated. Some alcohols were oxidized to carbonyl compounds with 2-MIBC and 2-MIBC/alumina under reflux in ultrasonically supported medium. Some aromatic compounds were also brominated with 2-MIBC under reflux in ultrasonically supported medium.Furthermore, in order to optimize the reaction conditions, the storage time of 2-MIBC, substrate: 2-MIBC ratio and effect of different solvent were investigated. It has been observed that 2-MIBC was obtained with a very high yield and it was found to be non-acidic, stable, easy to work with, easy to prepare, non hygroscopic and long lasting its activity.In this work, a new alumina-supported bromochromate compound was synthesized by using ultrasonic wave for the first time in the literature. In addition, conversion of alcohols/oximes to carbonyl compounds with this reagent was done for the first time in an alumina/ ultrasonically assisted environment. The results obtained with the use of ultrasonic waves in the oxidation reaction of alumina supported 2-MIBC and in the bromination reaction of 2-MIBC were found to be advantageous compared to the results obtained with halogenated chromium reagents in the present literature.