Yayınlar & Eserler

Yayın Ağı
SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Phenyl-benzyl-ureas with pyridazinone motif: Potent soluble epoxide hydrolase inhibitors with enhanced pharmacokinetics and efficacy in a paclitaxel-induced neuropathic pain model

LENGERLİ D., Bakht A., ÇALIŞKAN K., Dahlke P., BAL N. B., Jordan P. M., et al.
European Journal of Medicinal Chemistry , cilt.290, 2025 (SCI-Expanded) identifier identifier identifier

Isoxazole-pyrimidine derivatives as TACC3 inhibitors: A novel modality to targeted cancer therapy

LENGERLİ D., Çalışkan Ö. A., ÇALIŞKAN K., Saatci Ö., Lim C., Vempati S., et al.
Bioorganic Chemistry , cilt.156, 2025 (SCI-Expanded) identifier identifier

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification

Saatci O., Akbulut O., Cetin M., Sikirzhytski V., ÜNER M., LENGERLİ D., et al.
Cell Death and Differentiation , cilt.30, sa.5, ss.1305-1319, 2023 (SCI-Expanded) Creative Commons License Sürdürülebilir Kalkınma identifier identifier identifier

The 1,2,3-triazole 'all-in-one' ring system in drug discovery: a good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool.

Lengerli D., Ibis K., Nural Y., Banoglu E.
Expert opinion on drug discovery , cilt.17, sa.11, ss.1209-1236, 2022 (SCI-Expanded) identifier identifier identifier

Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with in Vitro Growth Inhibitory and in Vivo Antitumor Activity

Turanll S., NALBAT E., LENGERLİ D., İBİŞ K., Güntekin Ergün S., Akhan Güzelcan E., et al.
ACS Omega , cilt.7, sa.41, ss.36206-36226, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier

A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug Candidate

Akbulut O., Lengerli D., Saatci O., Duman E., ŞEKER U. Ö. Ş., Isik A., et al.
MOLECULAR CANCER THERAPEUTICS , cilt.19, sa.6, ss.1243-1254, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma identifier identifier identifier
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler

Vicinal Diaryl-Substituted Compounds: Promising Therapeutics for Breast Cancer

NALBAT E., GÜNTEKİN ERGÜN S., TURANLI S., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., et al.
2024 Annual Congress of the European Association for Cancer Research (EACR 2024), Rotterdam, Hollanda, 10 - 13 Haziran 2024

Identifying the interactome of TACC3, a major driver in aggressive cancer cells with centrosome amplification

Saatci O., Akbulut O., Cetin M., Sikirzhytski V., ÜNER M., LENGERLİ D., et al.
San Antonio Breast Cancer Symposium, San-Antonio, Kuzey Mariana Adaları, 5 - 09 Aralık 2023 identifier

PYRIDAZINYL-PHENYL BENZYL UREA DERIVATIVES AS HUMAN SOLUBLE EPOXIDE HYDROLASE (sEH) INHIBITORS

Bakht A., LENGERLİ D., Jordan P. M., İBİŞ K., ÇALIŞKAN B., Werz O., et al.
Medicinal Chemistry Frontiers 2024, Utrecht, Hollanda, 08 Nisan 2024

Hepatocellular Carcinoma: Evaluation of Vicinal Diaryl Isoxazole and Pyrazole Derivatives with Implications for Oxidative Stress and Senescence-mediated Anti-tumor Mechanisms

NALBAT E., AKHAN GÜZELCAN E., TURANLI S., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., et al.
EASL Liver Cancer Summit 2024, 22 - 24 Şubat 2024

Exploring novel vicinal diaryl-substituted isoxazole and pyrazole derivatives as cytotoxic compounds for targeting breast cancer: Mechanisms and therapeutic potential

NALBAT E., GÜNTEKİN ERGÜN S., TURANLI S., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., et al.
XVIII. Tıbbi Biyoloji ve Genetik Kongresi, Ankara, Türkiye, 26 - 29 Ekim 2023

A NOVEL SERIES OF ANTIPYRINE-UREA ANALOGUES: DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE

LENGERLİ D.
International Multidisciplinary Symposium on Drug Research and Development (DRD) 2023, 4 - 06 Mayıs 2023

STUDIES ON THE SYNTHESIS AND ANTICANCER POTENTIAL OF NOVEL 2,4-DIAMINOPYRIMIDINE DERIVATIVES

Lengerli D., Akbulut Çalışkan Ö., Çalışkan B., Şahin Ö., Banoğlu E.
The 9th Young Medicinal Chemist Symposium (EFMC-YMCS 2022), Nice, Fransa, 8 - 09 Eylül 2022

DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL IMIDAZOLIDINONE-THIAZOLE AMIDE HYBRIDS AS INHIBITORS OF HUMAN SOLUBLE EPOXIDE HYDROLASE

İbiş K., Lengerli D., Jordan P. M., Çalışkan B., Werz O., Banoğlu E.
9th EFMC Young Medicinal Chemists' Symposium, Nice, Fransa, 8 - 09 Eylül 2022

TACC3 İnhı̇bı̇törü Yenı̇ 2,4-Dı̇amı̇nopı̇rı̇mı̇dı̇n Türevlerı̇nı̇n Sentezı̇, Antı̇-Kanser Etkı̇ Potansı̇yellerı̇ ve İlaç Benzerı̇ Özellı̇klerı̇nı̇n Değerlendı̇rı̇lmesı̇ Üzerı̇ne Çalışmalar

LENGERLİ D., AKBULUT ÇALIŞKAN Ö., ÇALIŞKAN B., ŞAHİN Ö., BANOĞLU E.
VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 Ağustos 2022 Sürdürülebilir Kalkınma

Synthesis of 3,4-Diaryl-5-methylisoxazoles with Potent Antiproliferative Activity Against a Panel of Human Liver and Breast Cancer Cell Lines

LENGERLİ D., TURANLİ S., ÇALIŞKAN B., AKHAN GÜZELCAN E., NALBAT E., ATALAY R., et al.
EFMC-ISMC EFMC-YMCS Virtual Poster Session, 09 Eylül 2020 Sürdürülebilir Kalkınma

Synthesis of New Vicinal Diaryl Five-Membered Heterocyclic Compounds with Potential Anticancer Activity

TURANLİ S., LENGERLİ D., ÇALIŞKAN B., AKHAN GÜZELCAN E., NALBAT E., ATALAY R., et al.
8th International Drug Chemistry Conference, 27 Şubat - 01 Mart 2020

A SMALL MOLECULE INHIBITOR OF TRANSFORMING ACIDICCOILED-COIL PROTEIN 3 (TACC3): A NOVEL THERAPEUTICSTRATEGY FOR THE TREATMENT OF BREAST CANCER

LENGERLİ D., Akbulut O., ÇALIŞKAN B., ŞAHİN Ö., BANOĞLU E.
11th Joint Meeting on Medicinal Chemistry 2019, PRAG, Çek Cumhuriyeti, 27 - 30 Haziran 2019 Sürdürülebilir Kalkınma

Abstract 3871: A novel TACC3 inhibitor as an anti-cancer agent in breast cancer

Akbulut O., LENGERLİ D., Saatci O., Duman E., Seker U., ÇALIŞKAN B., et al.
Experimental and Molecular Therapeutics, 29 Mart - 03 Nisan 2019 Sürdürülebilir Kalkınma

A Novel TACC3 inhibitor as an anti-cancer agent in breast cancer

AKBULUT ÇALIŞKAN Ö., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., ŞAHİN Ö.
30th EORTC-NCI-AACR Symposium, Dublin, İrlanda, 13 - 16 Kasım 2018
Metrikler

Yayın

21

Atıf (WoS)

56

H-İndeks (WoS)

3

Atıf (Scopus)

90

H-İndeks (Scopus)

4

Atıf (Scholar)

98

H-İndeks (Scholar)

4

Proje

3

Fikri Mülkiyet

28

Açık Erişim

2
BM Sürdürülebilir Kalkınma Amaçları