Dr. Öğr. Üyesi KÜBRA ÇALIŞKAN

Yayın Ağı

Makaleler 12

1. Harnessing structure-activity relationships to repurpose the FLAP inhibitor BRP-7 into potent and selective sEH inhibitors.

Çalışkan K., Karataş M., Jordan P. M., Çalışkan B., Werz O., Banoğlu E.

Bioorganic chemistry , cilt.165, ss.108997, 2025 (SCI-Expanded, Scopus)

2. Potent soluble epoxide hydrolase inhibitors based on thiazole-5-carboxamide structure with imidazolidinone moiety as a secondary pharmacophore

LENGERLİ D., KOÇ B., Jordan P. M., ÇALIŞKAN K., ÇALIŞKAN B., Werz O., et al.

Bioorganic Chemistry , cilt.163, 2025 (SCI-Expanded, Scopus)

3. Synthesis, molecular docking, and in vitro evaluation of 2,4-dichlorobenzylamide derivatives as soluble epoxide hydrolase (sEH) inhibitors

ÇALIŞKAN K., Sadak E., Jordan P. M., Werz O.

Organic Communications , cilt.18, sa.3, ss.166-176, 2025 (ESCI, Scopus)

4. Phenyl-benzyl-ureas with pyridazinone motif: Potent soluble epoxide hydrolase inhibitors with enhanced pharmacokinetics and efficacy in a paclitaxel-induced neuropathic pain model

LENGERLİ D., Bakht A., ÇALIŞKAN K., Dahlke P., BAL N. B., Jordan P. M., et al.

European Journal of Medicinal Chemistry , cilt.290, 2025 (SCI-Expanded, Scopus)

5. Isoxazole-pyrimidine derivatives as TACC3 inhibitors: A novel modality to targeted cancer therapy

LENGERLİ D., Çalışkan Ö. A., ÇALIŞKAN K., Saatci Ö., Lim C., Vempati S., et al.

Bioorganic Chemistry , cilt.156, 2025 (SCI-Expanded, Scopus)

6. Tirbanibulin (KX2-391) analog KX2-361 inhibits botulinum neurotoxin serotype A mediated SNAP-25 cleavage in pre- and post-intoxication models in cells

Koc D., ÇALIŞKAN K., Besarat P., BANOĞLU E., KİRİŞ E.

Drug Development Research , cilt.85, sa.6, 2024 (SCI-Expanded, Scopus)

7. Targeting TACC3 Induces Immunogenic Cell Death and Enhances T-DM1 Response in HER2-Positive Breast Cancer

Gedik M. E., Saatci O., Oberholtzer N., ÜNER M., Akbulut Caliskan O., Cetin M., et al.

CANCER RESEARCH , cilt.84, sa.9, ss.1475-1490, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

8. Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors.

Gür Maz Z. T., Koç B., Jordan P. M., İbiş K., Çalışkan B., Werz O., et al.

ACS OMEGA , cilt.8, sa.2, ss.2445-2454, 2023 (SCI-Expanded, Scopus)

9. The 1,2,3-triazole 'all-in-one' ring system in drug discovery: a good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool.

Lengerli D., Ibis K., Nural Y., Banoglu E.

Expert opinion on drug discovery , cilt.17, sa.11, ss.1209-1236, 2022 (SCI-Expanded, Scopus)

10. Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with in Vitro Growth Inhibitory and in Vivo Antitumor Activity

Turanll S., NALBAT E., LENGERLİ D., İBİŞ K., Güntekin Ergün S., Akhan Güzelcan E., et al.

ACS Omega , cilt.7, sa.41, ss.36206-36226, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

11. Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

Ibis K., NALBAT E., ÇALIŞKAN B., KAHRAMAN D. C., Cetin-Atalay R., BANOĞLU E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.221, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

ÇALIŞKAN B., NALBAT E., Ibis K., Guzelcan E. A., ATALAY R., BANOĞLU E.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.33, sa.1, ss.1352-1361, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 11

1. NOVEL INDOLE-CARBOXAMIDE DERIVATIVES AS HUMAN SOLUBLE EPOXIDE HYDROLASE (sEH) INHIBITORS

Koç B., Gür Maz Z. T., Jordan P. M., Çalışkan K., Çalışkan B., Werz O., et al.

X EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry , Porto, Portekiz, 31 Ağustos - 04 Eylül 2025, ss.269, (Özet Bildiri)

2. EVALUATION OF NOVEL THIAZOLE-5-CARBOXAMIDE-IMIDAZOLIDINONE DERIVATIVES AS POTENT HUMAN SOLUBLE EPOXIDE HYDROLASE INHIBITORS

LENGERLİ D., KOÇ B., JORDAN P. M., ÇALIŞKAN K., ÇALIŞKAN B., WERZ O., et al.

59th International Conference on Medicinal Chemistry (RICT 2025), Orleans, Fransa, 02 Temmuz 2025, (Özet Bildiri)

3. Novel Benzimidazole Amide Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors

Çalışkan K., Jordan P. M., Çalışkan B., Werz O., Banoğlu E.

58TH INTERNATIONAL CONFERENCE ON MEDICINAL CHEMISTRY, Bordeaux, Fransa, 3 - 05 Temmuz 2024, ss.188, (Özet Bildiri)

4. PYRIDAZINYL-PHENYL BENZYL UREA DERIVATIVES AS HUMAN SOLUBLE EPOXIDE HYDROLASE (sEH) INHIBITORS

Bakht A., LENGERLİ D., Jordan P. M., İBİŞ K., ÇALIŞKAN B., Werz O., et al.

Medicinal Chemistry Frontiers 2024, Utrecht, Hollanda, 08 Nisan 2024, (Özet Bildiri)

5. SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR DOCKING STUDIES OF NEW 1-(2-CHLOROPHENYL)UREA DERIVATIVES AS INHIBITORS OF HUMAN SOLUBLE EPOXIDE HYDROLASE

İbiş K.

International Multidisciplinary Symposium on Drug Research and Development (DRD) 2023, İzmir, Türkiye, 4 - 06 Mayıs 2023, ss.204, (Özet Bildiri)

6. Design, Synthesis and Biological Evaluation Of Novel Imidazolidinone-Thiazole Amide Hybrids As Inhibitors Of Human Soluble Epoxide Hydrolase

İBİŞ K., LENGERLİ D., JORDAN P., ÇALIŞKAN B., WERZ O., BANOĞLU E.

9th EFMC Young Medicinal Chemists' Symposium, Nice, Fransa, 08 Eylül 2022, (Özet Bildiri)

7. KARACİĞER KANSERİ KÖK HÜCRELERİ ÜZERİNDE İNHİBİTÖR ETKİYE SAHİP, POTANSİYEL ANTİKANSER AJANLAR OLARAK YENİ İZOKSAZOL-PİPERAZİN HİBRİTLERİNİN SENTEZİ VE BİYOLOJİK OLARAK DEĞERLENDİRİLMESİ

İbiş K., Nalbat E., Çalışkan B., Atalay R., Banoğlu E.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022, (Özet Bildiri) Sürdürülebilir Kalkınma

Metrikler

Yayın

Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

160

H-İndeks (WoS)

Atıf (Scopus)

170

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Proje

Fikri Mülkiyet

Açık Erişim

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