Asst. Prof. MAHMUT GÖZELLE

Publication Network

Articles 15

1. Design, synthesis, and biological evaluation of platinum(II) complexes bearing chiral 2-(1-hydroxyethyl)benzimidazole ligands as potential anticancer agents

Gözelle M., Güler E. M.

POLYHEDRON , vol.296, 2026 (SCI-Expanded, Scopus)

2. Structure-Guided Optimization and Biological Validation of 1,3,4-Thiadiazole-Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Aksel A. B., ÖZGENCİL F., BAKAR ATEŞ F., GÜNİNDİ H. B., Massarotti A., Ozkan E., et al.

DRUG DEVELOPMENT RESEARCH , vol.87, no.2, 2026 (SCI-Expanded, Scopus)

3. **Targeting SIRT2 with Oxadiazole/Thiadiazole-Based Acetamides: In Silico Screening and In Vitro Cytotoxicity Evaluation**

Aksel A. B., GÖZELLE M., BAKAR ATEŞ F., ÖZKAN Y., Ozkan E., EREN G.

POLYCYCLIC AROMATIC COMPOUNDS , vol.45, pp.2064-2086, 2025 (SCI-Expanded, Scopus)

4. In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits

Gözelle M., Bakar Ateş F., Massarotti A., Ozkan E., Gunindi H. B., Özkan Y., et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , vol.43, no.4, pp.1756-1767, 2025 (SCI-Expanded, Scopus)

5. Enzalutamide-human serum albumin interaction: Electrochemical exploration of complex formation and binding parameters

Chenguiti F., Bakirhan N. K., GÖZELLE M., Doulache M., Saidat B., Atici E. B., et al.

Microchemical Journal , vol.201, 2024 (SCI-Expanded, Scopus)

6. 2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition

Kaya S. G., Eren G., Massarotti A., Bakar-Ates F., Ozkan E., Gozelle M., et al.

DRUG DEVELOPMENT RESEARCH , vol.85, no.4, 2024 (SCI-Expanded, Scopus) Sustainable Development

7. Linker and tail group modifications on 2-((4-isopropyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-phenoxyphenyl)acetamide to improve SIRT2 inhibitory potency

GÖZELLE M., ÖZKAN Y., EREN G.

FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , vol.49, no.2, pp.317-332, 2024 (Scopus, TRDizin)

8. Synthesis of 2-Substitutedbenzimidazolium Tetrachloroplatinate(II) Compounds and Their Cytotoxic Activities on Different Cell Lines

Gözelle M., Kılıç Süloğlu A.

FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , vol.47, no.3, pp.281-292, 2022 (Scopus, TRDizin)

9. Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity

Gözelle M., Kaya S. G., Aksel A. B., Özkan E., Bakar Ateş F., Özkan Y., et al.

Bioorganic Chemistry , vol.123, pp.105746, 2022 (SCI-Expanded, Scopus) Sustainable Development

10. The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking

ŞÜKÜROĞLU M. K., GÖZELLE M., ÖZKAN Y., EREN G.

MEDICINAL CHEMISTRY RESEARCH , vol.30, no.10, pp.1915-1924, 2021 (SCI-Expanded, Scopus)

11. Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT

Yagci S., Gözelle M., Kaya S. G., Özkan Y., Aksel A. B., Bakar-Ates F., et al.

BIOORGANIC & MEDICINAL CHEMISTRY , vol.30, 2021 (SCI-Expanded, Scopus) Sustainable Development

12. Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors

Eren G., Bruno A., Guntekin-Ergun S., Atalay R., Ozgencil F., Özkan Y., et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING , vol.89, pp.60-73, 2019 (SCI-Expanded, Scopus) Sustainable Development

13. Studies on the synthesis, characterization, cytotoxic activities and plasmid DNA binding of platinum(II) complexes having 2-subsituted benzimidazole ligands

Gözelle M., Kılıç Süloğlu A., Selmanoğlu G., Ramazanoglu N., Açık L., Gumus F.

POLYHEDRON , vol.161, pp.298-308, 2019 (SCI-Expanded, Scopus) Sustainable Development

14. Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists

Adlere I., Sun S., Zarca A., Roumen L., Gözelle M., Viciano C. P., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , vol.162, pp.631-649, 2019 (SCI-Expanded, Scopus)

15. Synthesis, Crystal Structure, Spectroscopic and Density Functional Modelling Studies of The 2-Isopropylbenzimidazolium Tetrachloroplatinate(II) Monohydrate

Zeyrek C. T., ÜNVER H., GÖZELLE M., Dilek N., Gumus F.

GAZI UNIVERSITY JOURNAL OF SCIENCE , vol.30, no.1, pp.139-159, 2017 (ESCI, Scopus)

Papers Presented at Peer-Reviewed Scientific Conferences 12

1. Design and biological assessment of novel platinum(II) complexes with benzimidazole ligands against cancer cells

GÖZELLE M., GÜLER E. M.

7th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2024), Turkey, 2 - 04 October 2024, (Summary Text)

2. Platinum(II) complexes with 2-/3-/4-(benzimidazol-2-yl)phenol: Synthesis, characterization and in vitro cytotoxic activities

GÖZELLE M., ŞİMAY DEMİR Y. D.

6th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2023), Ankara, Turkey, 11 - 13 October 2023, (Summary Text)

3. Ariloksi Benzamit Yapısında Sirtuin İnhibitörü Olabilecek Bileşiklerin Tasarımı, Sentezi ve Biyolojik Aktivite Çalışmaları

YAĞCI S., GÖZELLE M., ÖZKAN Y., BAKAR ATEŞ F., EREN G.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Turkey, 26 - 29 August 2022, (Summary Text)

4. Application of pharmacophore-based virtual screening for novel SIRT6 inhibitors

GÖZELLE M.

4th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2021), Ankara, Turkey, 24 - 26 November 2021, (Summary Text)