EUROPEAN JOURNAL OF NUTRITION, vol.54, no.6, pp.895-904, 2015 (SCI-Expanded)
Article / Article
EUROPEAN JOURNAL OF NUTRITION
Science Citation Index Expanded (SCI-EXPANDED), Scopus
High-fructose corn syrup, Resveratrol, Hepatic lipid, FASN, SREBP-1c, IRS-1, eNOS, SIRT1, FATTY LIVER-DISEASE, INSULIN-RESISTANT CONDITIONS, TREATED RATS, NITRIC-OXIDE, SIGNALING PATHWAY, MICE, EXPRESSION, SIRT1, STEATOSIS, RECEPTOR
Gazi University Affiliated:
The increased consumption of high-fructose corn syrup (HFCS) may contribute to the worldwide epidemic of fatty liver. In this study, we have investigated whether HFCS intake (20 % beverages) influences lipid synthesis and accumulation in conjunction with insulin receptor substrate-1/2 (IRS-1; IRS-2), endothelial nitric oxide synthase (eNOS), sirtuin 1 (SIRT1) and inducible NOS (iNOS) expressions in liver of rats. Resveratrol was tested for its potential efficacy on changes induced by HFCS.