Atıf İçin Kopyala
SADİ G., Ergin V., Yilmaz G., Pektas M. B., Yildirim O. G., Menevse A., ...Daha Fazla
EUROPEAN JOURNAL OF NUTRITION, cilt.54, sa.6, ss.895-904, 2015 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
54
Sayı:
6
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Basım Tarihi:
2015
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Doi Numarası:
10.1007/s00394-014-0765-1
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Dergi Adı:
EUROPEAN JOURNAL OF NUTRITION
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.895-904
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Anahtar Kelimeler:
High-fructose corn syrup, Resveratrol, Hepatic lipid, FASN, SREBP-1c, IRS-1, eNOS, SIRT1, FATTY LIVER-DISEASE, INSULIN-RESISTANT CONDITIONS, TREATED RATS, NITRIC-OXIDE, SIGNALING PATHWAY, MICE, EXPRESSION, SIRT1, STEATOSIS, RECEPTOR
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Gazi Üniversitesi Adresli:
Evet
Özet
The increased consumption of high-fructose corn syrup (HFCS) may contribute to the worldwide epidemic of fatty liver. In this study, we have investigated whether HFCS intake (20 % beverages) influences lipid synthesis and accumulation in conjunction with insulin receptor substrate-1/2 (IRS-1; IRS-2), endothelial nitric oxide synthase (eNOS), sirtuin 1 (SIRT1) and inducible NOS (iNOS) expressions in liver of rats. Resveratrol was tested for its potential efficacy on changes induced by HFCS.