Doç. Dr. İRFAN ÇAPAN

Yayın Ağı

Makaleler 34

1. Steroidal arylidene hybrids with phenolic moieties: Integrated in silico, DFT, and electrochemical evaluation for therapeutic targeting

Qaoud M. T., Çapan İ., Saydam S., Servi S.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1351, 2026 (SCI-Expanded, Scopus)

2. Trifluoromethyl-pyrazole-carboxamides as COX inhibitors: synthesis, microed structural analysis, computational profiling, and biological evaluation

Hawash M., Shweiki N., Qaoud M. T., ÇAPAN İ., Abualhasan M., Kumar A., et al.

BMC CHEMISTRY , cilt.19, sa.1, 2025 (SCI-Expanded, Scopus)

3. Design, Synthesis, and Evaluation of Benzimidazole-Carbazole Hybrids Targeting Heat Shock Proteins-Mediated Apoptosis in Breast and Colon Cancer Cells

ÇAPAN İ., Al M., Guemues M., AÇIK L., AYDIN B., Celik A. B., et al.

DRUG DEVELOPMENT RESEARCH , cilt.86, sa.3, 2025 (SCI-Expanded, Scopus)

4. Novel carbazole-thiadiazole derivatives as α-amylase and α-glucosidase inhibitors: Design, biological evaluation, and computational insights

ÇAPAN İ., Hawash M., Qaoud M. T., Jaradat N.

BIOORGANIC CHEMISTRY , cilt.157, 2025 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

5. **Phosphazene Tripeptide Conjugates: Design, Synthesis, In Vitro Cytotoxicity and Genotoxicity, Molecular Interactions in Binding Pockets on Human Breast and Colon Cancer Cell Lines**

Çalışkan E., Yüksel F., ÇAPAN İ., TEKİN S., Bouzidi R., Qaoud M. T., et al.

CHEMMEDCHEM , cilt.20, sa.3, 2025 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

6. Next-Generation Carbazole-Linked 1,2,4-Triazole-Thione Derivatives: Strategic Design, Synthesis, Molecular Docking, and Evaluation of Antidiabetic Potential

Çapan İ., Hawash M., Qaoud M. T., Jaradat N.

ACS OMEGA , cilt.10, sa.1, ss.848-861, 2025 (SCI-Expanded, Scopus)

7. Development of tripeptide-cyclotriphosphazene derivatives: In vitro cytotoxicity, genotoxicity studies and molecular docking analysis within ovarian and prostate cancer cell line receptors

Kaplan A., Caliskan E., ÇAPAN İ., TEKİN S., Hassan M. N., Qaoud M. T., et al.

POLYHEDRON , cilt.264, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

8. Tripeptide linked dispiro cyclotriphosphazene conjugates: Synthesis, molecular docking analysis of compounds binding within cancer cell line receptors and in vitro cytotoxic and genotoxic activities

Çalışkan E., ÇAPAN İ., TEKİN S., Qaoud M. T., Biryan F., Koran K., et al.

BIOORGANIC CHEMISTRY , cilt.150, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

9. Deciphering the Biophysical Properties of Ion Channel Gating Pores by Coumarin–Benzodiazepine Hybrid Derivatives: Selective AMPA Receptor Antagonists

Qneibi M., Hawash M., GÜMÜŞ M., ÇAPAN İ., SERT Y., Bdir S., et al.

Molecular Neurobiology , cilt.61, sa.7, ss.4565-4576, 2024 (SCI-Expanded, Scopus)

10. Synthesis of novel carbazole hydrazine-carbothioamide scaffold as potent antioxidant, anticancer and antimicrobial agents

ÇAPAN İ., Hawash M., Qaoud M. T., Gulum L., Tunoglu E. N. Y., Cifci K. U., et al.

BMC CHEMISTRY , cilt.18, sa.1, 2024 (SCI-Expanded, Scopus)

11. Exploration of isoxazole analogs: Synthesis, COX inhibition, anticancer screening, 3D multicellular tumor spheroids, and molecular modeling

Hawash M., Abdallah S., KENANOĞLU M. F., Melhem Y., Abu Shamat M., Aghbar M., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.271, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

12. Synthesis of 2-Amino-1,3,4-Oxadiazoles Derivatives with Benzimidazole Skeleton

Han D., Çapan İ., Servi S.

MW Journal of Science , cilt.1, sa.1, ss.1-7, 2024 (Hakemli Dergi)

13. Design, synthesis, molecular docking and biological evaluation of new carbazole derivatives as anticancer, and antioxidant agents

Çapan İ., Hawash M., Jaradat N., Sert Y., Servi R., Koca İ.

BMC Chemistry , cilt.17, sa.1, 2023 (SCI-Expanded, Scopus)

14. Characterization and Investigation of Novel Benzodioxol Derivatives as Antidiabetic Agents: An In Vitro and In Vivo Study in an Animal Model

Hawash M., Al-Smadi D., Kumar A., Olech B., Dominiak P. M., Jaradat N., et al.

BIOMOLECULES , cilt.13, sa.10, ss.1-16, 2023 (SCI-Expanded, Scopus)

15. Substituted 1,2,4-Triazoles as Novel and Selective Inhibitors of Leukotriene Biosynthesis Targeting 5-Lipoxygenase-Activating Protein

Olğaç A., Çapan İ., Dahlke P., Jordan P. M., Werz O., Banoglu E.

ACS OMEGA , cilt.8, sa.34, ss.31293-31304, 2023 (SCI-Expanded, Scopus)

16. Synthesis, docking studies, in vitro cytotoxicity evaluation and DNA damage mechanism of new tyrosine-based tripeptides.

Çalışkan E., Kaplan A., Şekerci G., Çapan İ., Tekin S., Erkan S., et al.

Journal of biochemical and molecular toxicology , cilt.37, sa.8, 2023 (SCI-Expanded, Scopus)

17. The first peptide derivatives of dioxybiphenyl-bridged spiro cyclotriphosphazenes: In vitro cytotoxicity activities and DNA damage studies

Koran K., Çalışkan E., Altay Öztürk D., ÇAPAN İ., TEKİN S., SANDAL S., et al.

Bioorganic Chemistry , cilt.132, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

18. Design, Synthesis and Evaluation of Aryl-Tailored Oxadiazole-thiones as New Urease Inhibitors

Gür Maz Z. T., Caliskan H. B., Capan İ., Caliskan B., Özçelik B., Banoglu E.

CHEMISTRYSELECT , cilt.8, sa.8, 2023 (SCI-Expanded, Scopus)

19. Synthesis, molecular docking, molecular dynamics and evaluation of Drug-Likeness properties of the fused N-Formyl pyrazoline substituted new dehydroepiandrosterone derivatives

ÇAPAN İ., Shehu A., SERT Y., ÇELİK İ., EROL M., KOCA İ., et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.41, sa.6, ss.2492-2503, 2023 (SCI-Expanded, Scopus)

20. Experimental and computational studies of 1,5-diphenyl-pyrazole-3-carboxamide compounds as potential Cannabinoid receptor type 1

Koca I., Yakan M., Capan I., Sahin E., Sert Y.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1264, ss.1-13, 2022 (SCI-Expanded, Scopus)

21. Synthesis, DFT study, molecular docking and drug-likeness analysis of the heteroaryl substituted new pregnenolone derivatives

ÇAPAN İ., SERT Y., Shehu A., KOCA İ., Servi S.

Journal of Molecular Structure , cilt.1260, 2022 (SCI-Expanded, Scopus)

22. Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

Çapan İ., Jordan P. M., Olğaç A., Çalışkan B., Kretzer C., Werz O., et al.

ChemMedChem , cilt.17, sa.12, 2022 (SCI-Expanded, Scopus)

23. Methimazole Analogs as Urease Inhibitors: Synthesis, In Silico and In Vitro Evaluation

ÇAPAN İ.

CHEMISTRYSELECT , cilt.7, sa.4, 2022 (SCI-Expanded, Scopus)

24. Synthesis, dielectric properties, molecular docking and ADME studies of pyrrole-3-ones

Çapan İ., Gümüş M., Gokce H., Çetin H., Sert Y., Koca İ.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , cilt.40, sa.19, ss.8655-8671, 2022 (SCI-Expanded, Scopus)

25. Isolation of amygdalin epimer at high diastereomeric purity and its structural characterization by spectroscopic and Q-TOF LC-MS methods

Sabir P. R., ÇAPAN İ., AYSAL A. İ., Servi S.

JOURNAL OF CHEMICAL METROLOGY , cilt.15, sa.2, ss.172-185, 2021 (ESCI, Scopus, TRDizin)

26. Synthesis of carbazole-based acetyl benzohydrazides targeting urease enzyme inhibition

ÇAPAN İ.

ORGANIC COMMUNICATIONS , cilt.14, sa.3, ss.270-279, 2021 (ESCI, Scopus, TRDizin)

27. Synthesis, DFT Study, Molecular Docking and Drug-Likeness Analysis of the New Hydrazine-1-Carbothioamide, Triazole and Thiadiazole Derivatives: Potential Inhibitors of HSP90

Çapan İ., Servi S., Yıldırım İ., Sert Y.

CHEMISTRYSELECT , cilt.6, sa.23, ss.5838-5846, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

28. Synthesis and Anticancer Evaluation of Benzimidazole Derivatives Having Norbornene/Dibenzobarrelene Skeletons and Different Functional Groups

ÇAPAN İ., Servi S., Dalkilic S., Dalkilic L. K.

CHEMISTRYSELECT , cilt.5, sa.45, ss.14393-14398, 2020 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

29. Synthesis of New C2-Symmetric Chiral Benzimidazole Derivatives Having Norbornene/Dibenzobarrelene Skeletons

ÇAPAN İ., SERVİ S.

LETTERS IN ORGANIC CHEMISTRY , cilt.17, sa.10, ss.801-805, 2020 (SCI-Expanded, Scopus)

30. Synthesis of Indole and Benzimidazole Substituted Novel 16-Arylidene Steroid Derivatives

Karatas S., ÇAPAN İ., SERVİ S.

LETTERS IN ORGANIC CHEMISTRY , cilt.16, sa.11, ss.884-890, 2019 (SCI-Expanded, Scopus)

31. A new barbiturate-based centrosymmetric compound: Joint experimental/DM investigation of the structural, spectroscopic and surface properties

Sen F., Capan İ., Dincer M., Cukurovali A.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1155, ss.278-287, 2018 (SCI-Expanded, Scopus)

32. Synthesis of Heterocyclic-Substituted Novel Hydroxysteroids with Regioselective and Stereoselective Reactions

Kolo A. M., Ipek E., Capan İ., Servi S.

JOURNAL OF HETEROCYCLIC CHEMISTRY , cilt.55, sa.2, ss.492-497, 2018 (SCI-Expanded, Scopus)

33. Synthesis of novel aza-heterocyclic derivatives from diester and diacid chlorides having the dibenzobarrelene skeleton

ÇAPAN İ., SERVİ S.

SYNTHETIC COMMUNICATIONS , cilt.48, sa.10, ss.1164-1171, 2018 (SCI-Expanded, Scopus)

34. Synthesis of novel C-2 substituted imidazoline derivatives having the norbornene/dibenzobarrelene skeletons

ÇAPAN İ., SERVİ S.

ARKIVOC , ss.131-142, 2018 (SCI-Expanded, Scopus)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 24

1. A Tale of Two 5-Lipoxygenase Activating Protein (FLAP) Inhibitors

OLĞAÇ A., TURANLI S., ÇAPAN İ., Dahlke P., ERGÜL A. G., Jordan P. M., et al.

Gordon Research Seminar on Computer Aided Drug Design, Vermont, Amerika Birleşik Devletleri, 15 - 16 Temmuz 2023, (Özet Bildiri)

2. A Tale of Two Diverse Sets of Novel 5-Lipoxygenase Activating Protein (FLAP) Inhibitors

OLĞAÇ A., TURANLI S., ÇAPAN İ., Dahlke P., ERGÜL A. G., Jordan P. M., et al.

International Multidisciplinary Symposium on Drug Research and Development (DRD) 2023, İzmir, Türkiye, 04 Mayıs 2023, (Özet Bildiri)

3. Yeni Dipeptit Sübstitüe Siklotrifosfazen Türevlerinin İn Vitro Sitotoksisite Aktiviteleri ve DNA Hasarı Özellikleri

Çalışkan E., Altay Öztürk D., Çapan İ., Tekin S., Koran K., Sandal S., et al.

34. Ulusal Kimya Kongresi, Yalova, Türkiye, 1 - 06 Eylül 2022, ss.1, (Özet Bildiri)

4. HSP90’ın Potansiyel İnhibitörü Olarak ((1H-benzimidazol-2-il)karbamoil)-L-fenilalaninat Türevlerinin Sentezi ve Moleküler Kenetlenme Analizi

Çapan İ., Sert Y., Karaca T. D., Koca İ.

34. Ulusal Kimya Kongresi, Yalova, Türkiye, 1 - 06 Eylül 2022, ss.1, (Özet Bildiri)

5. Antimigratory Activity of Methimazole Derivative Compound

ŞİMAY DEMİR Y. D., DÖNMEZ M. O., ÇAPAN İ.

10th International Medicine and Health Sciences Researches Congress, Ankara, Türkiye, 27 - 28 Ağustos 2022, (Özet Bildiri)

6. Synthesis of Tyrosine Based Peptides and Investigation of DNA Damage and Cytotoxicity

ÇALIŞKAN E., KORAN K., GÖRGÜLÜ A. O., ÇAPAN İ., TEKİN S., SANDAL S.

5th Organic Chemistry Congress 2021, Türkiye, 14 Ekim 2021, (Özet Bildiri)

7. Üreaz Inhibitörü Olarak Yeni Oksadiazol-2-on Türevlerinin Sentezi

ÇAPAN İ.

33. Ulusal Kimya Kongresi, Türkiye, 07 Ekim 2021, (Özet Bildiri)

8. Ostim Organize Sanayi Bölgesindeki Şebeke Sularında Akrilamid, Fitalat ve Bisfenol-A (BPA) Miktarının Sıvı Kromatografisi Kütle Spektrometresi ile Tayini

Çapan İ., Yalnız H. A., Arslaner İ. B., Süslü D.

33. Ulusal Kimya Kongresi, 7 - 09 Ekim 2021, ss.311, (Özet Bildiri)

9. SYNTHESIS AND CHARACTERIZATION OF NEW ORGANIC COMPOUNDS CONTAINING PYRIMIDINE

Çapan İ., Koca İ.

6th INTERNATIONAL ZEUGMA CONFERENCE ON SCIENTIFIC RESEARCHES June 19-20, 2021, GAZIANTEP, TURKEY, 19 - 20 Haziran 2021, ss.297-302, (Tam Metin Bildiri)

10. Synthesis of Potential Biologically Active Molecules; Thiosemicarbazide and 1,2,4-Triazole Derivatives Having the Carbazole Hybrid

ÇAPAN İ.

8. International Drug Chemistry Conference, Türkiye, 27 Şubat 2020, (Özet Bildiri)

11. Investigation of thermal and dielectric properties of morpholine/triazine-based acryl amide polymer composites

ÇAPAN İ., ÇEVRİMLİ B. S., BİRYAN F.

2nd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2019), 28 - 29 Haziran 2019, (Özet Bildiri)

12. Synthesis of Pyrazoline Derivatives that are Exocyclic Substituted with the Steroid Molecule

ÇAPAN İ., Shehu A., SERVİ S.

2nd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2019), 28 - 29 Haziran 2019, (Özet Bildiri)

13. Synthesis of Novel C-2 Substituted Imidazoline Derivatives from Diacid Chlorides Having the Norbornene Skeletons

Çapan İ., Servi S.

International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2018), Ankara, Türkiye, 26 - 27 Nisan 2018, ss.1282, (Özet Bildiri)

14. Synthesis of Norbornene-Based Compounds Containing Ester and Benzimidazole

Çapan İ., Servi S.

International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2018), Ankara, Türkiye, 26 - 27 Nisan 2018, ss.456, (Özet Bildiri)

15. Synthesis of Novel C-2 Substituted Imidazoline DerivativesFrom Diacid Chlorides Having The Dibenzobarrelene Skeletons

ÇAPAN İ., SERVİ S.

Uluslararası Katılımlı 6. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Türkiye, 22 Mart 2018, (Özet Bildiri)

16. The Unexpected Products from the Reaction of 2-Amino Benzimidazole or 2-Amino Imidazoline with Dibenzobarrelene -Based Diester and Diacid Chlorides

ÇAPAN İ., SERVİ S.

Uluslararası Katılımlı 6. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Türkiye, 22 - 25 Mart 2018, (Özet Bildiri)

17. QUANTUM CHEMICAL, SPECTROSCOPIC AND CRYSTALSTRUCTURE STUDIES oF 1-(2-(3-METHYL-3-PHENYLCYCLOBUTYL)-2-OXOE THYL)- 1 H-INDOLE-3 -CARBALDEHYDE

ACAR B., DİNÇER M., ÇAPAN İ., ÇUKUROVALI A.

33th lNTERNATlONAL PHYSICS CONGRESS, Muğla, Türkiye, 6 - 10 Eylül 2017, (Özet Bildiri)

Kitaplar 1

1. N-Heterocycles Having One and Two Nitrogen Atoms As Corrosion Inhibitors

Gümüş M., Çapan İ., Koca İ.

Handbook of Heterocyclic Corrosion Inhibitors Principles and Applications, Chandrabhan Verma, Editör, CRC, New York , New York, ss.448-473, 2023

Metrikler

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307

H-İndeks (WoS)

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306

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Atıf (Scholar)

367

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Yayın (WoS)

Yayın (Scopus)

Atıf (WoS)

H-İndeks (WoS)

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H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

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