Dr. Öğr. Üyesi YAPRAK DİLBER ŞİMAY DEMİR

Yayın Ağı

Makaleler 20

1. Targeting SASP with FDA-approved agents: minoxidil and diazoxide as potential senomorphic agents in cancer therapy

Şimay Demir Y. D., Ahmed I. M., Tayyar T., Özdemir A., Ark M.

TURKISH JOURNAL OF BIOCHEMISTRY , ss.1-12, 2025 (SCI-Expanded, Scopus, TRDizin) Sürdürülebilir Kalkınma

2. Caveolae and Rho Kinase: their implication of the senescent cell morphology and the secretion of the SASP in HeLa and A549 cancer cells.

Şimay Demir Y. D., Mohammed Ahmed I., Özdemir A., Ark M.

Medical oncology (Northwood, London, England) , cilt.42, sa.11, ss.475, 2025 (SCI-Expanded)

3. Evaluating the Effect of SASP Factors on the Proliferation of Cancer Cells using A Comparative Analysis of Three Distinct Methodologies

Şimay Demir Y. D., Tayyar T., Özdemir A., Ark M.

JOURNAL OF VISUALIZED EXPERIMENTS , cilt.223, sa.e68883, ss.1-19, 2025 (SCI-Expanded)

4. Chemotherapy-Induced Cellular Senescence: A Comprehensive Review of Clinical Methodologies and Treatment Outcomes

Yağbasan F. Ö., Şimay Demir Y. D., Ark M.

Turkish Journal of Clinics and Laboratory , cilt.16, sa.3, ss.653-664, 2025 (Hakemli Dergi)

5. EvaluationoftheinvivoassessmentofLycopodiumcomplanatumL.ssp.chamaecyparissus(A.BraunexMutel)D€ollextractsonTNF-aandIL-6

Özçelik B., Orhan I., Oyardi O., Demir Y. S., Turan T.

SOUTH AFRICAN JOURNAL OF BOTANY , cilt.182, sa.1, ss.266-271, 2025 (SCI-Expanded)

6. YENİ BİR SENOMORFİK İLAÇ ADAYI OLARAK HİDROKLOROTİYAZİD

Şimay Demir Y. D., Akgül S.

ANKARA UNIVERSITESI ECZACILIK FAKULTESI DERGISI , cilt.49, sa.2, ss.6-10, 2025 (Scopus)

7. DNA Binding and Anticancer Activity of Tetrazole-Based Schiff Bases and Their Platinum (II) Complexes via In Vitro and In Silico Endpoints

Okuş F., SARI N., ŞİMAY DEMİR Y. D., HASANOĞLU ÖZKAN E., ÜNAL F., YÜZBAŞIOĞLU D., et al.

Polycyclic Aromatic Compounds , 2025 (SCI-Expanded)

8. Cardiotrophin 1: a novel SASP marker in senescent MCF-7 cells

ÖZDEMİR A. O., TAYYAR T., ŞİMAY DEMİR Y. D., ARK M.

FEBS OPEN BIO , cilt.14, ss.318, 2024 (SCI-Expanded)

9. Temporal regulation of gene expression and pathways in chemotherapy-induced senescence in HeLa cervical cancer cell line

Sucularli C., Şimay Demir Y. D., Özdemir A., Ark M.

BIOSYSTEMS , cilt.237, 2024 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

10. Screening of medicinal plant extracts as novel DNA gyrase inhibitors

Oyardı Ö., Özçelik B., Caliskan U. K., Şimay Demir Y. D., Ark M.

INDIAN JOURNAL OF TRADITIONAL KNOWLEDGE , cilt.22, sa.1, ss.211-219, 2023 (SCI-Expanded, Scopus)

11. Senescent cells and SASP in cancer microenvironment: New approaches in cancer therapy.

Özdemir A., Şimay Demir Y. D., Yeşilyurt Z. E., Ark M.

Advances in protein chemistry and structural biology , cilt.133, ss.115-158, 2023 (Scopus)

12. The implication of ROCK 2 as a potential senotherapeutic target via the suppression of the harmful effects of the SASP: Do senescent cancer cells really engulf the other cells?

Demir Y. D., Özdemir A., Sucularli C., Benhür E., Ark M.

CELLULAR SIGNALLING , cilt.84, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

13. Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells

Şimay Demir Y. D., Özdemir A., Özdemir R. G., Cevher S. C., Çalışkan B., Ark M.

JOURNAL OF PHARMACY AND PHARMACOLOGY , cilt.73, sa.6, ss.808-815, 2021 (SCI-Expanded, Scopus)

14. A novel proteolytic cleavage of ROCK 1 in cell death: Not only by caspases 3 and 7 but also by caspase 2

Özdemir A., İbişoğlu B., Şimay Demir Y. D., Benhür E., Valipour F., Ark M.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , cilt.547, ss.118-124, 2021 (SCI-Expanded, Scopus)

15. Novel palladium(II) complexes of N-(5-nitro-salicylidene)-Schiff bases: Synthesis, spectroscopic characterization and cytotoxicity investigation

Özdemir Ö., Gurkan P., Şimay Demir Y. D., Ark M.

JOURNAL OF MOLECULAR STRUCTURE , cilt.1207, 2020 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

16. Antioxidant and Cytotoxic Activity Studies in Series of Higher Amino Acid Schiff Bases

Özdemir Ö., Gürkan P., Şimay Demir Y. D., Ark M.

GAZI UNIVERSITY JOURNAL OF SCIENCE , cilt.33, sa.3, ss.646-660, 2020 (ESCI, Scopus, TRDizin) Sürdürülebilir Kalkınma

17. The connection between the cardiac glycoside-induced senescent cell morphology and Rho/Rho kinase pathway

Simay Y. D., ÖZDEMİR A., Ibisoglu B., ARK M.

CYTOSKELETON , cilt.75, sa.11, ss.461-471, 2018 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

18. Promising anticancer activity of Cyclotrichium niveum L. extracts through induction of both apoptosis and necrosis

ÖZDEMİR A., Yildiz M., ŞENOL DENİZ F. S., Simay Y. D., Iboglu B., GÖKBULUT A., et al.

FOOD AND CHEMICAL TOXICOLOGY , cilt.109, ss.898-909, 2017 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

19. Cardiac glycoside-induced cell death and Rho/Rho kinase pathway: Implication of different regulation in cancer cell lines

ÖZDEMİR A., Simay Y. D., Ibisoglu B., Yaren B., Bulbul D., ARK M.

STEROIDS , cilt.109, ss.29-43, 2016 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

20. Ouabain induces Rho-dependent rock activation and membrane blebbing in cultured endothelial cells

Ozdemir A., Ibisoglu B., Simay Y. D., Polat B., Ark M.

MOLECULAR BIOLOGY , cilt.49, sa.1, ss.138-143, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 18

1. Targeting Therapy-Induced Senescence: Repurposing Approved Drugs to Suppress SASP in Cancer Cells

Özdemir A., Şimay Demir Y. D., Tayyar T., Mohammedahmed İ., Bozan E. B., Ark M.

2025 Cold Spring Harbor meeting: 89th Symposium: Senescence & Aging, New York, Amerika Birleşik Devletleri, 28 Mayıs - 01 Haziran 2025, ss.156, (Özet Bildiri)

2. Theophylline-induced HDAC activation as a novel senomorphic strategy—Suppression of SASP in senescent cancer cells

Ark M., Şimay Demir Y. D., Tayyar T., Turan T., Özdemir A.

2025 Cold Spring Harbor meeting: 89th Symposium: Senescence & Aging, New York, Amerika Birleşik Devletleri, 28 Mayıs - 01 Haziran 2025, ss.58, (Özet Bildiri)