Education Information
2012 - 2016
2012 - 2016Doctorate
Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Dr), Turkey
2009 - 2013
2009 - 2013Undergraduate
Anadolu University, Faculty Of Busıness Admınıstratıon, Department Of Busıness, Turkey
2007 - 2012
2007 - 2012Undergraduate
Ankara University, Eczacılık Fakültesi, Eczacılık Pr., Turkey
Dissertations
2016
2016Doctorate
ANTİLÖKOTRİEN ETKİLİ 1,2,5-TRİSÜBSTİTÜE BENZİMİDAZOL TÜREVLERİNİN GELİŞTİRİLMESİ ÜZERİNDE YAPILAN ÇALIŞMALAR
Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Dr)
Research Areas
Pharmacology and Therapeutics
Pharmaceutical Chemistry
Health Sciences
Academic Titles / Tasks
2023 - Continues
2023 - ContinuesAssociate Professor
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2022 - 2023
2022 - 2023Assistant Professor
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2016 - 2022
2016 - 2022Research Assistant PhD
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2012 - 2016
2012 - 2016Research Assistant
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Managerial Experience
2022 - 2024
2022 - 2024Ölçme Değerlendirme Kurulu Üyesi
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Non Academic Experience
2014 - 2014
2014 - 2014Erasmus Öğrenim Hareketliliği
Università degli Studi di Perugia
Courses
Published journal articles indexed by SCI, SSCI, and AHCI
2024
2024Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors
Gür Maz T., Dahlke P., Gizem Ergül A., OLĞAÇ A., Jordan P. M., ÇALIŞKAN B., et al.
BIOORGANIC CHEMISTRY
, vol.147, 2024 (SCI-Expanded)
2023
2023Design, Synthesis and Evaluation of Aryl-Tailored Oxadiazole-thiones as New Urease Inhibitors
Gür Maz Z. T., Caliskan H. B., Capan İ., Caliskan B., Özçelik B., Banoglu E.
CHEMISTRYSELECT
, vol.8, no.8, 2023 (SCI-Expanded)
2023
2023Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors.
Gür Maz Z. T., Koç B., Jordan P. M., İbiş K., Çalışkan B., Werz O., et al.
ACS OMEGA
, vol.8, no.2, pp.2445-2454, 2023 (SCI-Expanded)
2022
2022Development and molecular modeling studies of new thiadiazole piperazine urea derivatives as potential fatty acid amide hydrolase inhibitors
Gür Maz Z. T., Turanlı S., Çalışkan H. B., Çalışkan B., Banoğlu E.
ARCHIV DER PHARMAZIE
, vol.355, no.8, pp.1-11, 2022 (SCI-Expanded)
2022
2022A Series of Thiadiazolyl-Benzenesulfonamides Incorporating an Aromatic Tail as Isoform-Selective, Potent Carbonic Anhydrase II/XII Inhibitors
Banoglu E., Ercanlı T., Gür Maz T., Vullo D., Bonardi A., Gratteri P., et al.
CHEMMEDCHEM
, vol.17, no.10, 2022 (SCI-Expanded)
2022
2022Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase
Ergül A. G., Maz T. G., Kretzer C., Olğaç A., Jordan P. M., Çalışkan B., et al.
European Journal of Medicinal Chemistry
, vol.231, 2022 (SCI-Expanded)
2022
2022Shifting the Biosynthesis of Leukotrienes Toward Specialized Pro-Resolving Mediators by the 5-Lipoxygenase-Activating Protein (FLAP) Antagonist BRP-201
Kretzer C., Jordan P. M., Bilancia R., Rossi A., Maz T. G., BANOĞLU E., et al.
Journal of Inflammation Research
, vol.15, pp.911-925, 2022 (SCI-Expanded)
2021
2021Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy
Gurses T., OLĞAÇ A., Garscha U., GÜR MAZ Z. T., BAL N. B., Uludag O., et al.
BIOORGANIC CHEMISTRY
, vol.112, 2021 (SCI-Expanded)
2021
2021Exploration of anti-tyrosinase effect of Geranium glaberrimum Boiss. & Heldr. with in silico approach and survey of 21 Geranium species
Celikler Ozer O., Erdoğan Orhan İ., Çalışkan B., Senol Deniz F. S., Gokbulut A., Gur Maz T., et al.
JOURNAL OF HERBAL MEDICINE
, vol.27, 2021 (SCI-Expanded)
2020
2020Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors
Uslu A. G., Maz T. G., Nocentini A., BANOĞLU E., Supuran C. T., ÇALIŞKAN B.
BIOORGANIC CHEMISTRY
, vol.95, 2020 (SCI-Expanded)
2019
2019Optimisation by design of experiment of benzimidazol-2-one synthesis under flow conditions
Mostarda S., Maz T. G., Piccinno A., Cerra B., Banoğlu E.
Molecules
, vol.24, no.13, 2019 (SCI-Expanded)
2019
2019Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors
GÜR MAZ Z. T., ŞENOL DENİZ F. S., Shekfeh S., ERDOĞAN ORHAN İ., BANOĞLU E., ÇALIŞKAN B.
LETTERS IN DRUG DESIGN & DISCOVERY
, vol.16, no.1, pp.36-44, 2019 (SCI-Expanded)
2018
2018Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis
Gür Maz Z. T., Çalışkan B., Banoğlu E.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, vol.153, pp.34-48, 2018 (SCI-Expanded)
2018
2018Identification of multi-target inhibitors of leukotriene and prostaglandin E-2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7
GÜR MAZ Z. T., ÇALIŞKAN B., Garscha U., OLĞAÇ A., Schubert U. S., Gerstmeier J., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, vol.150, pp.876-899, 2018 (SCI-Expanded)
Articles Published in Other Journals
2023
2023Synthesis of some piperazine/piperidine amides of chromone-2-carboxylic acid as potential soluble epoxide hydrolase (sEH) inhibitors
GÜR MAZ Z. T., ÇALIŞKAN H. B.
ORGANIC COMMUNICATIONS
, vol.16, 2023 (ESCI)
2023
2023DESIGN AND SYNTHESIS OF SOME ARYLHYDRAZONE DERIVATIVES AS POTENTIAL FAAH INHIBITORS
Gür Maz Z. T., Çalışkan H. B., Turanlı S.
ANKARA UNIVERSITESI ECZACILIK FAKULTESI DERGISI
, vol.47, no.1, pp.111-119, 2023 (Scopus)
2021
2021Synthesis and evaluation of antibacterial and antimycobacterial activities of some new pyrazole derivatives
Gür Maz Z. T., Karaca N., Levent S., Çalışkan B., Demirci F., Banoğlu E.
JOURNAL OF RESEARCH IN PHARMACY
, vol.25, no.5, pp.531-539, 2021 (ESCI)
2018
2018Crystal structure and Hirshfeld surface analysis of 1-(2,4-dichlorobenzyl)-5-methyl-N-(thiophene-2-sulfonyl)-1H-pyrazole-3-carboxamide
Aydın A., Akkurt M., Gür Maz Z. T., Banoğlu E.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
, vol.74, pp.747-757, 2018 (ESCI)
2018
2018Crystal structure and Hirshfeld surface analysis of methyl 1-(2,4-dichlorobenzyl)-5-methyl-1H-pyrazole-3-carboxylate
Aydın A., Akkurt M., Gür Maz Z. T., Banoğlu E.
European Journal of Chemistry , vol.9, no.4, pp.347-352, 2018 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2023
2023Evaluation of Indole Based Carboxamide Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors
GÜR MAZ Z. T.
EUROASIA International Congress on Scientific Researches and Recent Trends-X, Baku, Azerbaijan, 16 - 17 February 2023
2023
2023Ibuprofen Based Piperidine Amides as Potential Fatty Acid Amide Hydrolase (FAAH) inhibitors
Gür Maz Z. T., Turanlı S.
The 16th International Scientific Research Congress, Ankara, Turkey, 11 - 12 March 2023
2022
2022Evaluation of Oxadiazole Derivatives as Promising Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors
GÜR MAZ Z. T., ERGÜL A. G., JORDAN P. M., ÇALIŞKAN B., WERZ O., BANOĞLU E.
XXVll EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2022), Nice, France, 4 - 08 September 2022
2022
2022Novel Microsomal Prostaglandin E2 Synthase-1 (MPGES-1) Inhibitors as a New Modality To Treat Inflammation
ÇALIŞKAN B., ERGÜL A. G., GÜR MAZ Z. T., KRETZER C., OLĞAÇ A., JORDAN P. M., et al.
XXVll EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2022), Nice, France, 4 - 08 September 2022
2022
2022NOVEL BENZOTHIAZOLE DERIVATIVESAS MICROSOMAL PROSTAGLANDINE E2SYNTHASE-1 (mPGES-1) INHIBITORS
YALÇIN T., GÜR MAZ Z. T., KRETZER C., ÇALIŞKAN B., WERZ O., BANOĞLU E.
9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022
2022
2022SELECTIVE OR DUAL INHIBITORS OF INFLAMMATORY PGE2 AND LTB4 BIOSYNTHESIS BY TARGETING mPGES-1 AND FLAP TO INTERVENE WITH INFLAMMATORY DEREGULATION
BANOĞLU E., ÇALIŞKAN B., ERGÜL A. G., GÜR MAZ Z. T., OLĞAÇ A., WERZ O.
The Sixth International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-6), Gaziantep, Turkey, 26 - 28 May 2022
2022
2022Discovery of Novel Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors: A New Modality to Treat Inflammation
Banoğlu E., Çalışkan B., Ergül A. G., Gür Maz Z. T., Kretzer C., Olğaç A., et al.
10th International Drug Chemistry Conference, Antalya, Turkey, 10 - 13 March 2022
2021
2021Para Kumarik Asidin Heteroarilalkil Amid Türevlerinin Sentezi ve Yağ Asidi Amid Hidrolaz (FAAH) İnhibitör Aktiviteleri
GÜR MAZ Z. T.
33. Ulusal Kimya Kongresi, Turkey, 07 October 2021
2021
2021NOVEL PIPERAZINYL UREA DERIVATIVES AS POTENTIAL FATTY ACID AMIDE HYDROLASE (FAAH) INHIBITORS
TURANLI S., ÇALIŞKAN H. B., GÜR MAZ Z. T., ÇALIŞKAN B., BANOĞLU E.
3rd International Gazi Pharma Symposium Series, 08 September 2021
2021
20212(3H)-BENZOXAZOLONE DERIVATIVES AS POTENTIAL FATTY ACID AMIDE HYDROLASE (FAAH) INHIBITORS
GÜR MAZ Z. T.
3rd International Gazi Pharma Symposium Series, Turkey, 08 September 2021
2020
2020Discovery of Multitarget Inhibitors in the Arachidonic Acid Pathway by Targeting FLAP/5-LO/mPGES-1 for Intervention with Inflammatory Deregulation
BANOĞLU E., ÇALIŞKAN B., GÜR MAZ Z. T., OLĞAÇ A., Garscha U., Werz O.
8th International Drug Chemistry Conference, Antalya, Turkey, 27 February - 01 March 2020
2018
2018EVOLUTION OF SELECTIVE FLAP INHIBITOR BRP-7 INTO MULTI-TARGET INHIBITOR OF FLAP, 5-LO AND MPGES-1 IN THE ARACHIDONIC ACID PATHWAY
GÜR MAZ Z. T., ÇALIŞKAN B., OLĞAÇ A., GERSTMEIER J., GARSCHA U., WERZ O., et al.
EFMC International Symposium on Medicinal Chemistry, Ljubljana, Slovenia, 2 - 06 September 2018, pp.231
2018
2018ANTİLÖKOTRİEN ETKİLİ 1,2,5-TRİSÜBSTİTÜEBENZİMİDAZOL TÜREVLERİNİN GELİŞTİRİLMESİ ÜZERİNDE YAPILAN ÇALIŞMALAR
GÜR MAZ Z. T., ÇALIŞKAN B., GERSTMEIER J., OLĞAÇ A., GARSCHA U., WERZ O., et al.
V. ULUSAL FARMASÖTİK KİMYA KONGRESİ, Erzurum, Turkey, 28 April - 01 May 2018
2018
2018Discovery of Tyrosinase Inhibitors from Geranium glaberrimum Boiss. Heldr. Using In Vitro and In Silico Methods
Çelikler Ö., ŞENOL DENİZ F. S., ÇALIŞKAN B., GÜR MAZ Z. T., KAHRAMAN A., ERDOĞAN ORHAN İ., et al.
The 4th Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-2018), 18 - 22 April 2018
2018
2018Discovery and Development of Novel Anti-cancer and Anti-inflammatory Compounds: Medicinal Chemistry Challenges
BANOĞLU E., ÇALIŞKAN B., GÜR MAZ Z. T., OLĞAÇ A., İBİŞ K., Akhan Güzelcam E., et al.
The 4th International Symposium on Pharmaceutical and Biomedical Sciences, Kumamoto, Japan, 17 March 2018
2017
2017FROM BATCH TO CONTINUOUS FLOW CHEMISTRY:DOE-ASSISTED OPTIMIZATION OF BENZIMIDAZOL-2-ONESYNTHESIS
GÜR Z. T., MOSTARDA S., PICCINNO A., ÇALIŞKAN B., BANOĞLU E., GIOIELLO A.
2nd International Gazi Pharma Symposium Series, 11 - 13 October 2017
2017
2017Developing Multi-target Inhibitors of Arachidonic Acid Pathway Based on the FLAP Inhibitor BRP-7
GÜR Z. T., ÇALIŞKAN B., GERSTMEIER J., OLĞAÇ A., GARSCHA U., WERZ O., et al.
2nd International Gazi Pharma Symposium Series, 11 - 13 October 2017
2017
2017Tirozinaz İnhibitör Etkili Yeni Sinnamik Asit Türevleri
ÇALIŞKAN B., GÜR Z. T., ŞENOL F. S., SHEKFEH S., ERDOĞAN ORHAN İ., BANOĞLU E.
29. Ulusal Kimya Kongresi, Turkey, 10 - 14 September 2017, pp.452
2017
2017Bioisosteric Tuning of FLAP Inhibitor BRP-7 Towards a More Potent Antiinmlammatory Agent with Multiligand Inhibitor Properties in the Arachidonic Acid (AA) Pathway
GÜR Z. T., ÇALIŞKAN B., OLĞAÇ A., GERSTMEIER J., GARSCHA U., WERZ O., et al.
EFMC-ASMC’xx17 EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, 27 - 31 August 2017
2017
2017Araşidonik asit yolağında çoklu ligand (FLAP/5-LO/mPGES-1) özellikte inhibitör etkili BRP-7 türevlerinin geliştirilmesi
BANOĞLU E., GÜR Z. T., ÇALIŞKAN B., GERSTMEIER J., OLĞAÇ A., GARSCHA U., et al.
1. Anadolu Üniversitesi Eczacılık Sempozyumu, Eskişehir, Turkey, 1 - 02 June 2017, pp.10
2016
2016Novel BRP 7 Derivatives Targeting FLAP Potent Inhibitors of Leukotriene Biosynthesis
GÜR Z. T., ÇALIŞKAN B., GERSTMEIER J., GARSCHA U., OLĞAÇ A., WERZ O., et al.
3rd EFMC Young Medicinal Chemist Symposium, Manchester, United Kingdom, 1 - 02 September 2016
2016
2016EXPLORATION OF THE CHEMICAL SPACE AROUND C 5 POSITION OF THE BENZIMIDAZOLE NUCLEUS IN BRP 7 TOWARDS MORE POTENT INHIBITORS OF HUMAN 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP
GÜR Z. T., ÇALIŞKAN B., Gerstmeier J., OLĞAÇ A., nikels F., werz o., et al.
EFMC International Symposium on Medicinal Chemistry, Manchester, United Kingdom, 28 August - 01 September 2016
2015
2015STRUCTURE BASED DESIGN AND SYNTHESIS OF NOVEL BRP 7 DERIVATIVES BEARING C 5 POLAR SUSBTITUENTS AS POTENT FLAP INHIBITORS
GÜR Z. T., OLĞAÇ A., Gerstmeiner J., Macchiarulo A., Werz O., ÇALIŞKAN B., et al.
GPSS 2015, Antalya, Turkey, 12 - 15 November 2015
2014
2014Structure-Based Design and Synthesis of Novel BRP-7 Derivatives as Potent FLAP Inhibitors: Insights from MolecularDynamics Simulations.
OLĞAÇ A., GÜR Z. T., CAROTTI A., ÇALIŞKAN B., GERSTMEIER J., WERZ O., et al.
EFMC International Symposium on Medicinal Chemistry, LİZBON, Portugal, 7 - 11 September 2014, pp.162
Supported Projects
2024 - Continues
2024 - ContinuesBazı Yeni İndol Türevi Çözünür Epoksit Hidrolaz İnhibitörlerinin Geliştirilmesi Üzerine Çalışmalar
Project Supported by Higher Education Institutions
GÜR MAZ Z. T. (Executive), BANOĞLU E., KOÇ B., ÇALIŞKAN B., İBİŞ K., WERZ O., et al.
2019 - 2023
2019 - 2023
Yeni Mikrozomal Prostaglandin E2 Sentaz-1 (Mpges-1) İnhibitörlerinin Geliştirilmesi Üzerine Çalışmalar
TUBITAK Project
(Project Abstract)
Banoğlu E. (Executive), Gür Maz Z. T., Uludağ M. O., Çalışkan B., Olğaç A., Bal N. B.
2020 - 2022
2020 - 2022Yeni Piperazinilüre Türevlerinin sentezi ve FAAH İnhibitörü Aktivitelerinin İncelenmesi
Project Supported by Higher Education Institutions
GÜR MAZ Z. T. (Executive), BANOĞLU E., ÇALIŞKAN B., TURANLİ S.
2020 - 2022
2020 - 2022Yeni Tiyadiazol Türevlerinin sentezi ve Karbonik Anhidraz İnhibitörü Aktivitelerinin Karakterizasyonu
Project Supported by Higher Education Institutions
BANOĞLU E. (Executive), GÜR MAZ Z. T., ERCANLI T.
2017 - 2019
2017 - 2019Pirazol-5-karboksilik asit sülfonamit türevlerinin sentezi ve antimikrobiyal aktivitelerinin değerlendirilmesi
Project Supported by Higher Education Institutions
Gür Maz Z. T. (Executive), Çalışkan B., Banoğlu E., Demirci F.
2013 - 2016
2013 - 2016
5 Lipoksijenaz aktive edici protein FLAP inhibitörlerinin geliştirilmesi
TUBITAK Project
(Project Abstract)
Banoğlu E. (Executive), Çalışkan B.
Patent
2023
2023BENZIMIDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
Patent
Pending / Applied, The Invention Recourse Number: PCT/TR2023/050887 , Standard Registration
2022
2022BENZİMİDAZOL TÜREVİ MİKROZOMAL PROSTAGLANDİN E2 SENTAZ-1 (mPGES-1) İNHİBİTÖRLERİ
Patent
Pending / Applied, The Invention Recourse Number: 2022/011123 , Standard Registration
Memberships / Tasks in Scientific Organizations
2012 - Continues
2012 - ContinuesTürk Farmasötik ve Medisinal Kimya Derneği
Member
Mobility Activity
2014 - 2014
2014 - 2014Erasmus Programme
Student Mobility
Universita Degli Studi di Perugia, Italy
Congress and Symposium Activities
04 September 2022 - 08 September 2022
04 September 2022 - 08 September 2022