Prof. Dr. BURCU ÇALIŞKAN

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Phenyl-benzyl-ureas with pyridazinone motif: Potent soluble epoxide hydrolase inhibitors with enhanced pharmacokinetics and efficacy in a paclitaxel-induced neuropathic pain model

LENGERLİ D., Bakht A., ÇALIŞKAN K., Dahlke P., BAL N. B., Jordan P. M., et al.

European Journal of Medicinal Chemistry , cilt.290, 2025 (SCI-Expanded)

Isoxazole-pyrimidine derivatives as TACC3 inhibitors: A novel modality to targeted cancer therapy

LENGERLİ D., Çalışkan Ö. A., ÇALIŞKAN K., Saatci Ö., Lim C., Vempati S., et al.

Bioorganic Chemistry , cilt.156, 2025 (SCI-Expanded)

2-Phenylbenzothiazoles featuring heteroaryl sulfonamide end-capping substructures as developable mPGES-1 inhibitors

Yalcin T., Jordan P. M., OLĞAÇ A., Dahlke P., GÜR MAZ Z. T., BANOĞLU E., et al.

ARCHIV DER PHARMAZIE , cilt.358, sa.1, 2025 (SCI-Expanded)

Novel Benzimidazole Derivatives as Potent Inhibitors of Microsomal Prostaglandin E<sub>2</sub> Synthase 1 for the Potential Treatment of Inflammation, Pain, and Fever

Ergul A. G., Jordan P. M., Dahlke P., BAL N. B., OLĞAÇ A., Uludag O., et al.

JOURNAL OF MEDICINAL CHEMISTRY , cilt.67, sa.23, ss.21143-21162, 2024 (SCI-Expanded)

Novel 1,3,4-oxadiazole derivatives as highly potent microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors

Gür Maz T., Dahlke P., Gizem Ergül A., OLĞAÇ A., Jordan P. M., ÇALIŞKAN B., et al.

BIOORGANIC CHEMISTRY , cilt.147, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

Targeting TACC3 Induces Immunogenic Cell Death and Enhances T-DM1 Response in HER2-Positive Breast Cancer

Gedik M. E., Saatci O., Oberholtzer N., ÜNER M., Akbulut Caliskan O., Cetin M., et al.

CANCER RESEARCH , cilt.84, sa.9, ss.1475-1490, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification

Saatci O., Akbulut O., Cetin M., Sikirzhytski V., ÜNER M., LENGERLİ D., et al.

Cell Death and Differentiation , cilt.30, sa.5, ss.1305-1319, 2023 (SCI-Expanded)

Design, Synthesis and Evaluation of Aryl-Tailored Oxadiazole-thiones as New Urease Inhibitors

Gür Maz Z. T., Caliskan H. B., Capan İ., Caliskan B., Özçelik B., Banoglu E.

CHEMISTRYSELECT , cilt.8, sa.8, 2023 (SCI-Expanded)

Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors.

Gür Maz Z. T., Koç B., Jordan P. M., İbiş K., Çalışkan B., Werz O., et al.

ACS OMEGA , cilt.8, sa.2, ss.2445-2454, 2023 (SCI-Expanded)

Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with in Vitro Growth Inhibitory and in Vivo Antitumor Activity

Turanll S., NALBAT E., LENGERLİ D., İBİŞ K., Güntekin Ergün S., Akhan Güzelcan E., et al.

ACS Omega , cilt.7, sa.41, ss.36206-36226, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition

TURANLİ S., Ergul A. G., Jordan P. M., OLĞAÇ A., ÇALIŞKAN B., Werz O., et al.

ACS OMEGA , cilt.7, sa.41, ss.36354-36365, 2022 (SCI-Expanded)

Development and molecular modeling studies of new thiadiazole piperazine urea derivatives as potential fatty acid amide hydrolase inhibitors

Gür Maz Z. T., Turanlı S., Çalışkan H. B., Çalışkan B., Banoğlu E.

ARCHIV DER PHARMAZIE , cilt.355, sa.8, ss.1-11, 2022 (SCI-Expanded)

Discovery and Optimization of Piperazine Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

Çapan İ., Jordan P. M., Olğaç A., Çalışkan B., Kretzer C., Werz O., et al.

ChemMedChem , cilt.17, sa.12, 2022 (SCI-Expanded)

Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase

Ergül A. G., Maz T. G., Kretzer C., Olğaç A., Jordan P. M., Çalışkan B., et al.

European Journal of Medicinal Chemistry , cilt.231, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells

Ibis K., NALBAT E., ÇALIŞKAN B., KAHRAMAN D. C., Cetin-Atalay R., BANOĞLU E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.221, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy

Gurses T., OLĞAÇ A., Garscha U., GÜR MAZ Z. T., BAL N. B., Uludag O., et al.

BIOORGANIC CHEMISTRY , cilt.112, 2021 (SCI-Expanded)

Antimigratory effect of pyrazole derivatives through the induction of STAT1 phosphorylation in A549 cancer cells

Şimay Demir Y. D., Özdemir A., Özdemir R. G., Cevher S. C., Çalışkan B., Ark M.

JOURNAL OF PHARMACY AND PHARMACOLOGY , cilt.73, sa.6, ss.808-815, 2021 (SCI-Expanded)

Exploration of anti-tyrosinase effect of Geranium glaberrimum Boiss. & Heldr. with in silico approach and survey of 21 Geranium species

Celikler Ozer O., Erdoğan Orhan İ., Çalışkan B., Senol Deniz F. S., Gokbulut A., Gur Maz T., et al.

JOURNAL OF HERBAL MEDICINE , cilt.27, 2021 (SCI-Expanded)

A Highly Potent TACC3 Inhibitor as a Novel Anticancer Drug Candidate

Akbulut O., Lengerli D., Saatci O., Duman E., ŞEKER U. Ö. Ş., Isik A., et al.

MOLECULAR CANCER THERAPEUTICS , cilt.19, sa.6, ss.1243-1254, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

Evaluation of Cytotoxic Activity of New Benzimidazole-Piperazine Hybrids Against Human MCF-7 and A549 Cancer Cells

ÖZDEMİR A., Thranli S., ÇALIŞKAN B., Arka M., BANOĞLU E.

Pharmaceutical Chemistry Journal , cilt.53, sa.11, ss.1036-1046, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors

Uslu A. G., Maz T. G., Nocentini A., BANOĞLU E., Supuran C. T., ÇALIŞKAN B.

BIOORGANIC CHEMISTRY , cilt.95, 2020 (SCI-Expanded)

A Multi-step Virtual Screening Protocol for the Identification of Novel Non-acidic Microsomal Prostaglandin E-2 Synthase-1 (mPGES-1) Inhibitors

Shekfeh S., ÇALIŞKAN B., Fischer K., Yalcin T., Garscha U., Werz O., et al.

CHEMMEDCHEM , cilt.14, sa.2, ss.273-281, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors

GÜR MAZ Z. T., ŞENOL DENİZ F. S., Shekfeh S., ERDOĞAN ORHAN İ., BANOĞLU E., ÇALIŞKAN B.

LETTERS IN DRUG DESIGN & DISCOVERY , cilt.16, sa.1, ss.36-44, 2019 (SCI-Expanded)

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

ÇALIŞKAN B., NALBAT E., Ibis K., Guzelcan E. A., ATALAY R., BANOĞLU E.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.33, sa.1, ss.1352-1361, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis

Gür Maz Z. T., Çalışkan B., Banoğlu E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.153, ss.34-48, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Identification of multi-target inhibitors of leukotriene and prostaglandin E-2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7

GÜR MAZ Z. T., ÇALIŞKAN B., Garscha U., OLĞAÇ A., Schubert U. S., Gerstmeier J., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.150, ss.876-899, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

Garscha U., Voelker S., Pace S., Gerstmeier J., Emini B., Liening S., et al.

BIOCHEMICAL PHARMACOLOGY , cilt.119, ss.17-26, 2016 (SCI-Expanded)

Synthesis and biological evaluation of C(5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7

Levent S., Gerstmeier J., Olğaç A., Nikels F., Garscha U., Carotti A., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.122, ss.510-519, 2016 (SCI-Expanded) Sürdürülebilir Kalkınma

4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

Banoğlu E., Celikoglu E., Voelker S., Olğaç A., Gerstmeier J., Garscha U., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.113, ss.1-10, 2016 (SCI-Expanded)

Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl)pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell lines

Pirol S. C., ÇALIŞKAN B., Durmaz I., ATALAY R., BANOĞLU E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.87, ss.140-149, 2014 (SCI-Expanded)

The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)

Pergola C., Gerstmeier J., Moench B., Caliskan B., Luderer S., Weinigel C., et al.

British Journal of Pharmacology , cilt.171, sa.12, ss.3051-3064, 2014 (SCI-Expanded)

Chromatographic separation and biological evaluation of benzimidazole derivative enantiomers as inhibitors of leukotriene biosynthesis

Sardella R., Levent S., Ianni F., ÇALIŞKAN B., Gerstmeier J., Pergola C., et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS , cilt.89, ss.88-92, 2014 (SCI-Expanded)

Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation

Levent S., ÇALIŞKAN B., Ciftci M., ÖZKAN Y., Yenicesu I., ÜNVER H., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.64, ss.42-53, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

Synthesis and evaluation of analgesic, anti-inflammatory, and anticancer activities of new pyrazole-3(5)-carboxylic acid derivatives

ÇALIŞKAN B., Yilmaz A., Evren I., Menevse S., Uludag O., BANOĞLU E.

MEDICINAL CHEMISTRY RESEARCH , cilt.22, sa.2, ss.782-793, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

Overview of recent drug discovery approaches for new generation leukotriene A(4) hydrolase inhibitors

ÇALIŞKAN B., BANOĞLU E.

EXPERT OPINION ON DRUG DISCOVERY , cilt.8, sa.1, ss.49-63, 2013 (SCI-Expanded)

Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP)

BANOĞLU E., ÇALIŞKAN B., Luderer S., EREN G., Ozkan Y., Altenhofen W., et al.

BIOORGANIC & MEDICINAL CHEMISTRY , cilt.20, sa.12, ss.3728-3741, 2012 (SCI-Expanded) Sürdürülebilir Kalkınma

Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils

ÇALIŞKAN B., Luderer S., Ozkan Y., Werz O., BANOĞLU E.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.46, sa.10, ss.5021-5033, 2011 (SCI-Expanded) Sürdürülebilir Kalkınma

Synthesis, antioxidant and antimicrobial evaluation of simple aromatic esters of ferulic acid

Ergun B., ÇOBAN T., Onurdag F. K., BANOĞLU E.

Archives of Pharmacal Research , cilt.34, sa.8, ss.1251-1261, 2011 (SCI-Expanded)

Stable ester and amide conjugates of some NSAIDs as analgesic and antiinflammatory compounds with improved biological activity

ULUDAĞ M. O., Ergun B., Alkan D. A., Ercan N., Ozkan G. Y., BANOĞLU E.

Turkish Journal of Chemistry , cilt.35, sa.3, ss.427-439, 2011 (SCI-Expanded)

Synthesis of 1,5-diarylpyrazol-3-propanoic acids towards inhibition of cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4 formation

Ergun B., Teresa Nunez M., Labeaga L., Ledo F., Darlington J., Bain G., et al.

Arzneimittel-Forschung/Drug Research , cilt.60, sa.8, ss.497-505, 2010 (SCI-Expanded)

Synthesis and chromatographic resolution of conformationally constrained analogues of homotaurine

Fulco M. C., Marinozzi M., Ergun B., Sardella R., Natalini B., Pellicciari R.

TETRAHEDRON , cilt.65, sa.42, ss.8756-8762, 2009 (SCI-Expanded)

Screening and evaluation of antioxidant activity of some pyridazine derivatives

Caliskan-Erguen B., Suekueroglu M. K., ÇOBAN T., BANOĞLU E., SÜZEN S.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.23, sa.2, ss.225-229, 2008 (SCI-Expanded)

Synthesis of the amide derivatives of 3-[1-(3-pyridazinyl)-5-phenyl-1H-pyrazole-3-yl]propanoic acids as potential analgesic compounds

BANOĞLU E., Sukuroglu M. K., Ergun B., BAYTAŞ S., Aypar E., Aark M.

TURKISH JOURNAL OF CHEMISTRY , cilt.31, sa.6, ss.677-687, 2007 (SCI-Expanded)

Screening and evaluation of rat kidney aldose reductase inhibitory activity of some pyridazine derivatives

Sukuroglu M. K., Caliskan-Ergun B., Das-Evcimen N., Sarikaya M., Banoğlu E., Suzen S.

MEDICINAL CHEMISTRY RESEARCH , cilt.15, ss.443-451, 2007 (SCI-Expanded) Sürdürülebilir Kalkınma

Synthesis, analgesic, and anti-inflammatory activities of [6-(3,5-dimethyl-4-chloropyrazole-1-yl)-3(2H-pyridazinon-2-yl]acetamides

Sukuroglu M. K., Ergun B., Unlu S., Sahin M., Kupeli E., Yesilada E., et al.

ARCHIVES OF PHARMACAL RESEARCH , cilt.28, sa.5, ss.509-517, 2005 (SCI-Expanded)

Synthesis of amide derivatives of [6-(3,5-dimethylpyrazol-1-yl)-3(2H)- pyridazinone-2-yl]acetic acid and their analgesic and anti-inflammatory properties

BANOĞLU E., Akoglu C., Unlu S., Ergun B., Kupeli E., Yesilada E., et al.

Arzneimittel-Forschung/Drug Research , cilt.55, sa.9, ss.520-527, 2005 (SCI-Expanded)

Diğer Dergilerde Yayınlanan Makaleler

Synthesis and evaluation of antibacterial and antimycobacterial activities of some new pyrazole derivatives

Gür Maz Z. T., Karaca N., Levent S., Çalışkan B., Demirci F., Banoğlu E.

JOURNAL OF RESEARCH IN PHARMACY , cilt.25, sa.5, ss.531-539, 2021 (ESCI)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler

Vicinal Diaryl-Substituted Compounds: Promising Therapeutics for Breast Cancer

NALBAT E., GÜNTEKİN ERGÜN S., TURANLI S., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., et al.

2024 Annual Congress of the European Association for Cancer Research (EACR 2024), Rotterdam, Hollanda, 10 - 13 Haziran 2024

PYRIDAZINYL-PHENYL BENZYL UREA DERIVATIVES AS HUMAN SOLUBLE EPOXIDE HYDROLASE (sEH) INHIBITORS

Bakht A., LENGERLİ D., Jordan P. M., İBİŞ K., ÇALIŞKAN B., Werz O., et al.

Medicinal Chemistry Frontiers 2024, Utrecht, Hollanda, 08 Nisan 2024

Hepatocellular Carcinoma: Evaluation of Vicinal Diaryl Isoxazole and Pyrazole Derivatives with Implications for Oxidative Stress and Senescence-mediated Anti-tumor Mechanisms

NALBAT E., AKHAN GÜZELCAN E., TURANLI S., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., et al.

EASL Liver Cancer Summit 2024, 22 - 24 Şubat 2024

Exploring novel vicinal diaryl-substituted isoxazole and pyrazole derivatives as cytotoxic compounds for targeting breast cancer: Mechanisms and therapeutic potential

NALBAT E., GÜNTEKİN ERGÜN S., TURANLI S., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., et al.

XVIII. Tıbbi Biyoloji ve Genetik Kongresi, Ankara, Türkiye, 26 - 29 Ekim 2023

A Tale of Two 5-Lipoxygenase Activating Protein (FLAP) Inhibitors

OLĞAÇ A., TURANLI S., ÇAPAN İ., Dahlke P., ERGÜL A. G., Jordan P. M., et al.

Gordon Research Seminar on Computer Aided Drug Design, Vermont, Amerika Birleşik Devletleri, 15 - 16 Temmuz 2023

A Tale of Two Diverse Sets of Novel 5-Lipoxygenase Activating Protein (FLAP) Inhibitors

OLĞAÇ A., TURANLI S., ÇAPAN İ., Dahlke P., ERGÜL A. G., Jordan P. M., et al.

International Multidisciplinary Symposium on Drug Research and Development (DRD) 2023, İzmir, Türkiye, 04 Mayıs 2023

STUDIES ON THE SYNTHESIS AND ANTICANCER POTENTIAL OF NOVEL 2,4-DIAMINOPYRIMIDINE DERIVATIVES

Lengerli D., Akbulut Çalışkan Ö., Çalışkan B., Şahin Ö., Banoğlu E.

The 9th Young Medicinal Chemist Symposium (EFMC-YMCS 2022), Nice, Fransa, 8 - 09 Eylül 2022

DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL IMIDAZOLIDINONE-THIAZOLE AMIDE HYBRIDS AS INHIBITORS OF HUMAN SOLUBLE EPOXIDE HYDROLASE

İbiş K., Lengerli D., Jordan P. M., Çalışkan B., Werz O., Banoğlu E.

9th EFMC Young Medicinal Chemists' Symposium, Nice, Fransa, 8 - 09 Eylül 2022

Evaluation of Oxadiazole Derivatives as Promising Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors

GÜR MAZ Z. T., ERGÜL A. G., JORDAN P. M., ÇALIŞKAN B., WERZ O., BANOĞLU E.

XXVll EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2022), Nice, Fransa, 4 - 08 Eylül 2022

NOVEL BENZOTHIAZOLE DERIVATIVESAS MICROSOMAL PROSTAGLANDINE E2SYNTHASE-1 (mPGES-1) INHIBITORS

YALÇIN T., GÜR MAZ Z. T., KRETZER C., ÇALIŞKAN B., WERZ O., BANOĞLU E.

9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, Fransa, 8 - 09 Eylül 2022

Novel Microsomal Prostaglandin E2 Synthase-1 (MPGES-1) Inhibitors as a New Modality To Treat Inflammation

ÇALIŞKAN B., ERGÜL A. G., GÜR MAZ Z. T., KRETZER C., OLĞAÇ A., JORDAN P. M., et al.

XXVll EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2022), Nice, Fransa, 4 - 08 Eylül 2022

Karaciğer Kanseri Kök Hücreleri Üzerinde İnhibitör Etkiye Sahip, Potansiyel Antikanser Ajanlar Olarak Yeni İzoksazol-Piperazin Hibritlerinin Sentezi Ve Biyolojik Olarak Değerlendirilmesi

İBİŞ K., NALBAT E., ÇALIŞKAN B., ATALAY R., BANOĞLU E.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022

KARACİĞER KANSERİ KÖK HÜCRELERİ ÜZERİNDE İNHİBİTÖR ETKİYE SAHİP, POTANSİYEL ANTİKANSER AJANLAR OLARAK YENİ İZOKSAZOL-PİPERAZİN HİBRİTLERİNİN SENTEZİ VE BİYOLOJİK OLARAK DEĞERLENDİRİLMESİ

İbiş K., Nalbat E., Çalışkan B., Atalay R., Banoğlu E.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022 Sürdürülebilir Kalkınma

TACC3 İnhı̇bı̇törü Yenı̇ 2,4-Dı̇amı̇nopı̇rı̇mı̇dı̇n Türevlerı̇nı̇n Sentezı̇, Antı̇-Kanser Etkı̇ Potansı̇yellerı̇ ve İlaç Benzerı̇ Özellı̇klerı̇nı̇n Değerlendı̇rı̇lmesı̇ Üzerı̇ne Çalışmalar

LENGERLİ D., AKBULUT ÇALIŞKAN Ö., ÇALIŞKAN B., ŞAHİN Ö., BANOĞLU E.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 Ağustos 2022 Sürdürülebilir Kalkınma

Bazı Visinal Diaril Heterosiklik Bileşiklerin Antikanser Aktivitelerinin Araştırılması

Turanli S., Nalbat E., Akhan Güzelcan E., Atalay R., Çalışkan B., Banoğlu E.

VI.Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022, ss.42-44

SELECTIVE OR DUAL INHIBITORS OF INFLAMMATORY PGE2 AND LTB4 BIOSYNTHESIS BY TARGETING mPGES-1 AND FLAP TO INTERVENE WITH INFLAMMATORY DEREGULATION

BANOĞLU E., ÇALIŞKAN B., ERGÜL A. G., GÜR MAZ Z. T., OLĞAÇ A., WERZ O.

The Sixth International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-6), Gaziantep, Türkiye, 26 - 28 Mayıs 2022

Discovery of Novel Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors: A New Modality to Treat Inflammation

Banoğlu E., Çalışkan B., Ergül A. G., Gür Maz Z. T., Kretzer C., Olğaç A., et al.

10th International Drug Chemistry Conference, Antalya, Türkiye, 10 - 13 Mart 2022

Novel isoxazole- piperazine derivatives inhibit the stemness of HCC cells

NALBAT E., İBİŞ K., ÇALIŞKAN B., BANOĞLU E., ATALAY M. V., ATALAY R.

AASLD-TASL Digital Hepatology Meeting, Ankara, Türkiye, 15 Ocak 2022, ss.5-6

NOVEL PIPERAZINYL UREA DERIVATIVES AS POTENTIAL FATTY ACID AMIDE HYDROLASE (FAAH) INHIBITORS

TURANLI S., ÇALIŞKAN H. B., GÜR MAZ Z. T., ÇALIŞKAN B., BANOĞLU E.

3rd International Gazi Pharma Symposium Series, 08 Eylül 2021

Synthesis of 3,4-Diaryl-5-methylisoxazoles with Potent Antiproliferative Activity Against a Panel of Human Liver and Breast Cancer Cell Lines

LENGERLİ D., TURANLİ S., ÇALIŞKAN B., AKHAN GÜZELCAN E., NALBAT E., ATALAY R., et al.

EFMC-ISMC EFMC-YMCS Virtual Poster Session, 09 Eylül 2020 Sürdürülebilir Kalkınma

Vicinal Diaryl Heterocyclic Compounds with Potential Anticancer Activity

TURANLİ S., ÇALIŞKAN B., AKHAN GÜZELCAN E., GÜNTEKİN ERGÜN S., ATALAY R., BANOĞLU E.

EFMC-ISMC EFMC-YMCS Virtual Poster Session, 09 Eylül 2020

Synthesis of New Vicinal Diaryl Five-Membered Heterocyclic Compounds with Potential Anticancer Activity

TURANLİ S., LENGERLİ D., ÇALIŞKAN B., AKHAN GÜZELCAN E., NALBAT E., ATALAY R., et al.

8th International Drug Chemistry Conference, 27 Şubat - 01 Mart 2020

Discovery of Multitarget Inhibitors in the Arachidonic Acid Pathway by Targeting FLAP/5-LO/mPGES-1 for Intervention with Inflammatory Deregulation

BANOĞLU E., ÇALIŞKAN B., GÜR MAZ Z. T., OLĞAÇ A., Garscha U., Werz O.

8th International Drug Chemistry Conference, Antalya, Türkiye, 27 Şubat - 01 Mart 2020

A SMALL MOLECULE INHIBITOR OF TRANSFORMING ACIDICCOILED-COIL PROTEIN 3 (TACC3): A NOVEL THERAPEUTICSTRATEGY FOR THE TREATMENT OF BREAST CANCER

LENGERLİ D., Akbulut O., ÇALIŞKAN B., ŞAHİN Ö., BANOĞLU E.

11th Joint Meeting on Medicinal Chemistry 2019, PRAG, Çek Cumhuriyeti, 27 - 30 Haziran 2019 Sürdürülebilir Kalkınma

Abstract 3871: A novel TACC3 inhibitor as an anti-cancer agent in breast cancer

Akbulut O., LENGERLİ D., Saatci O., Duman E., Seker U., ÇALIŞKAN B., et al.

Experimental and Molecular Therapeutics, 29 Mart - 03 Nisan 2019 Sürdürülebilir Kalkınma

A Novel TACC3 inhibitor as an anti-cancer agent in breast cancer

AKBULUT ÇALIŞKAN Ö., LENGERLİ D., ÇALIŞKAN B., BANOĞLU E., ŞAHİN Ö.

30th EORTC-NCI-AACR Symposium, Dublin, İrlanda, 13 - 16 Kasım 2018

Antimigratory Effect of a Newly Sythesized Pyrazole Derivative Compound in A549 Cancer Cells

ÖZDEMİR A., Gönbe Özdemir R., ŞİMAY DEMİR Y. D., Cevher S. C., Şahinoğlu E., ÇALIŞKAN B., et al.

DGZ International Meeting, 17 - 19 Eylül 2018, cilt.44 Sürdürülebilir Kalkınma

Antimigratory Effect of a Newly Sythesized Pyrazole Derivative Compound in A549 Cancer Cells

ÖZDEMİR A., özdemir r., Şimay y., cevher s., şahinoğlu e., ÇALIŞKAN B., et al.

DGZ International Meeting, 17 - 19 Eylül 2018 Sürdürülebilir Kalkınma

EVOLUTION OF SELECTIVE FLAP INHIBITOR BRP-7 INTO MULTI-TARGET INHIBITOR OF FLAP, 5-LO AND MPGES-1 IN THE ARACHIDONIC ACID PATHWAY

GÜR MAZ Z. T., ÇALIŞKAN B., OLĞAÇ A., GERSTMEIER J., GARSCHA U., WERZ O., et al.

EFMC International Symposium on Medicinal Chemistry, Ljubljana, Slovenya, 2 - 06 Eylül 2018, ss.231

SYNTHESIS, CYTOTOXICITY AND STRUCTURE-ACTIVITYRELATIONSHIPS OF NOVEL ISOXAZOLE DERIVATIVES ASANTICANCER AGENTS

İbiş K., ÇALIŞKAN B., AKHAN GÜZELCAN E., Sinoplu E., ATALAY R., BANOĞLU E.

RICT 2018, 4 - 06 Temmuz 2018

SYNTHESIS AND ANTIPROLIFERATIVE EVALUATION OF NOVEL ISOXAZOLE-PIPERAZINE HYBRIDS

ÇALIŞKAN B., Sinoplu E., İbiş K., AKHAN GÜZELCAN E., ATALAY R., BANOĞLU E.

RICT 2018, 4 - 06 Temmuz 2018

ANTİLÖKOTRİEN ETKİLİ 1,2,5-TRİSÜBSTİTÜEBENZİMİDAZOL TÜREVLERİNİN GELİŞTİRİLMESİ ÜZERİNDE YAPILAN ÇALIŞMALAR

GÜR MAZ Z. T., ÇALIŞKAN B., GERSTMEIER J., OLĞAÇ A., GARSCHA U., WERZ O., et al.

V. ULUSAL FARMASÖTİK KİMYA KONGRESİ, Erzurum, Türkiye, 28 Nisan - 01 Mayıs 2018

Discovery of Tyrosinase Inhibitors from Geranium glaberrimum Boiss. Heldr. Using In Vitro and In Silico Methods

Çelikler Ö., ŞENOL DENİZ F. S., ÇALIŞKAN B., GÜR MAZ Z. T., KAHRAMAN A., ERDOĞAN ORHAN İ., et al.

The 4th Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-2018), 18 - 22 Nisan 2018

Discovery and Development of Novel Anti-cancer and Anti-inflammatory Compounds: Medicinal Chemistry Challenges

BANOĞLU E., ÇALIŞKAN B., GÜR MAZ Z. T., OLĞAÇ A., İBİŞ K., Akhan Güzelcam E., et al.

The 4th International Symposium on Pharmaceutical and Biomedical Sciences, Kumamoto, Japonya, 17 Mart 2018 Sürdürülebilir Kalkınma

Developing Multi-target Inhibitors of Arachidonic Acid Pathway Based on the FLAP Inhibitor BRP-7

GÜR Z. T., ÇALIŞKAN B., GERSTMEIER J., OLĞAÇ A., GARSCHA U., WERZ O., et al.

2nd International Gazi Pharma Symposium Series, 11 - 13 Ekim 2017

FROM BATCH TO CONTINUOUS FLOW CHEMISTRY:DOE-ASSISTED OPTIMIZATION OF BENZIMIDAZOL-2-ONESYNTHESIS

GÜR Z. T., MOSTARDA S., PICCINNO A., ÇALIŞKAN B., BANOĞLU E., GIOIELLO A.

2nd International Gazi Pharma Symposium Series, 11 - 13 Ekim 2017

Discovery of Dual FLAP/mPGES-1 Inhibitors for Intervention with Inflammatory Diseases:Medicinal Chemistry Challenges

BANOĞLU E., ÇALIŞKAN B., GÜR Z. T., OLĞAÇ A.

Turkish Japanese Workshop on Bioorganic Medicinal Chemistry Natural Products, 14 Eylül 2017

Tirozinaz İnhibitör Etkili Yeni Sinnamik Asit Türevleri

ÇALIŞKAN B., GÜR Z. T., ŞENOL F. S., SHEKFEH S., ERDOĞAN ORHAN İ., BANOĞLU E.

29. Ulusal Kimya Kongresi, Türkiye, 10 - 14 Eylül 2017, ss.452

Bioisosteric Tuning of FLAP Inhibitor BRP-7 Towards a More Potent Antiinmlammatory Agent with Multiligand Inhibitor Properties in the Arachidonic Acid (AA) Pathway

GÜR Z. T., ÇALIŞKAN B., OLĞAÇ A., GERSTMEIER J., GARSCHA U., WERZ O., et al.

EFMC-ASMC’xx17 EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, 27 - 31 Ağustos 2017

Discovery of Novel Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors Using Structure-Based Virtual Screening.

Shekfeh S., Katrin F., ÇALIŞKAN B., Garscha U., Werz O., BANOĞLU E.

EFMC-ASMC 2017 International Symposium on Advances in Synthetic and Medicinal Chemistry, 27 - 31 Ağustos 2017

Araşidonik asit yolağında çoklu ligand (FLAP/5-LO/mPGES-1) özellikte inhibitör etkili BRP-7 türevlerinin geliştirilmesi

BANOĞLU E., GÜR Z. T., ÇALIŞKAN B., GERSTMEIER J., OLĞAÇ A., GARSCHA U., et al.

1. Anadolu Üniversitesi Eczacılık Sempozyumu, Eskişehir, Türkiye, 1 - 02 Haziran 2017, ss.10

5-Sübstitüe-Benzimidazol Türevi Bileşiğin Farelerde Analjezik ve Antienflamatuvar Aktivite Tarama Çalışması

Göker S., HAN S., ÇALIŞKAN B., BANOĞLU E., ULUDAĞ M. O.

3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.732

İzoksazol Türevi Bileşiklerin in-vivo Analjezik ve Antienflamatuvar Aktivitesi Üzerinde Çalışmalar

Örnek Ö., HAN S., ÇALIŞKAN B., BANOĞLU E., ULUDAĞ M. O.

3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.738

Diarilpirazol Türevi Bileşiğin (BRP-42) Analjezik ve Antienflamatuvar Aktivitesi Üzerinde Çalışmalar

GÖKER G., HAN S., ÇALIŞKAN B., BANOĞLU E., ULUDAĞ M. O.

3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.752

Anticancer activity of novel benzimidazole derivatives against MCF-7 cancer cells

ÖZDEMİR A., UZUNOĞLU S., ÇALIŞKAN B., BANOĞLU E., ARK M.

Experimental Biology 2017, Chicago, 22 - 26 Nisan 2017, cilt.31 Sürdürülebilir Kalkınma

Anticancer activity of novel benzimidazole derivatives against MCF-7 cancer cells

ÖZDEMİR A., Uzunoglu S., ÇALIŞKAN B., BANOĞLU E., ARK M.

Experimental Biology Meeting, Illinois, Amerika Birleşik Devletleri, 22 - 26 Nisan 2017, cilt.31 Sürdürülebilir Kalkınma

Novel BRP 7 Derivatives Targeting FLAP Potent Inhibitors of Leukotriene Biosynthesis

GÜR Z. T., ÇALIŞKAN B., GERSTMEIER J., GARSCHA U., OLĞAÇ A., WERZ O., et al.

3rd EFMC Young Medicinal Chemist Symposium, Manchester, Birleşik Krallık, 1 - 02 Eylül 2016

Discovery of 4 5 Diarylisoxazol 3 Carboxylic Acid Skeleton as a Novel Chemotype for Inhibition of 5 Lipoxygenase Activating Proteın FLAP

ÇALIŞKAN B., ÇELİKOĞLU E., GERSTMEIER J., VOELKER S., GARSCHA U., OLĞAÇ A., et al.

EFMC International Symposium on Medicinal Chemistry 2016, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016

EXPLORATION OF THE CHEMICAL SPACE AROUND C 5 POSITION OF THE BENZIMIDAZOLE NUCLEUS IN BRP 7 TOWARDS MORE POTENT INHIBITORS OF HUMAN 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP

GÜR Z. T., ÇALIŞKAN B., Gerstmeier J., OLĞAÇ A., nikels F., werz o., et al.

EFMC International Symposium on Medicinal Chemistry, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016

DISCOVERY OF 4 5 DIARYLISOXAZOL 3 CARBOXYLIC ACID SKELETON AS A NOVEL CHEMOTYPE FOR INHIBITION OF 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP

ÇALIŞKAN B., çelikoğlu e., gerstmeier j., voelker s., garscha u., OLĞAÇ A., et al.

EFMC International Symposium on Medicinal Chemistry, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016

STRUCTURE BASED DESIGN AND SYNTHESIS OF NOVEL BRP 7 DERIVATIVES BEARING C 5 POLAR SUSBTITUENTS AS POTENT FLAP INHIBITORS

GÜR Z. T., OLĞAÇ A., Gerstmeiner J., Macchiarulo A., Werz O., ÇALIŞKAN B., et al.

GPSS 2015, Antalya, Türkiye, 12 - 15 Kasım 2015

Structure-Based Design and Synthesis of Novel BRP-7 Derivatives as Potent FLAP Inhibitors: Insights from MolecularDynamics Simulations.

OLĞAÇ A., GÜR Z. T., CAROTTI A., ÇALIŞKAN B., GERSTMEIER J., WERZ O., et al.

EFMC International Symposium on Medicinal Chemistry, LİZBON, Portekiz, 7 - 11 Eylül 2014, ss.162

Kitaplar

Genel Anestezikler

GÜR MAZ Z. T., ÇALIŞKAN B.

Farmasötik Kimya Akıl Notları, ŞİMŞEK RAHİME, Editör, Güneş Tıp Kitabevleri, ss.121-131, 2025

Metrikler

Yayın

106

Atıf (WoS)

764

H-İndeks (WoS)

Atıf (Scopus)

884

H-İndeks (Scopus)

Atıf (Scholar)

1143

H-İndeks (Scholar)

Proje

Fikri Mülkiyet

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler