Prof. Dr. YEŞİM ÖZKAN

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition

Kaya S. G., Eren G., Massarotti A., Bakar-Ates F., Ozkan E., Gozelle M., et al.

DRUG DEVELOPMENT RESEARCH , cilt.85, sa.4, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits

GÖZELLE M., BAKAR ATEŞ F., Massarotti A., Ozkan E., Gunindi H. B., ÖZKAN Y., et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS , 2023 (SCI-Expanded)

Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity

Gözelle M., Kaya S. G., Aksel A. B., Özkan E., Bakar Ateş F., Özkan Y., et al.

Bioorganic Chemistry , cilt.123, ss.105746, 2022 (SCI-Expanded) Sürdürülebilir Kalkınma

Identification of novel antiplatelet agents by targeting Glycoprotein VI: A combined virtual screening study

OLĞAÇ S., OLĞAÇ A., YENİCESU İ., ÖZKAN Y.

BIOORGANIC CHEMISTRY , cilt.121, 2022 (SCI-Expanded)

Indoleamine-2,3-dioxygenase-related anti-inflammatory effects of 3-aminobenzamide and infliximab in experimental colitis

Menekse E., Aydin S., Aydin O. U., Sahin D., Akca G., Eroglu A., et al.

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA , cilt.68, sa.3, ss.362-366, 2022 (SCI-Expanded)

The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking

ŞÜKÜROĞLU M. K., GÖZELLE M., ÖZKAN Y., EREN G.

MEDICINAL CHEMISTRY RESEARCH , cilt.30, sa.10, ss.1915-1924, 2021 (SCI-Expanded)

Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT

Yagci S., Gözelle M., Kaya S. G., Özkan Y., Aksel A. B., Bakar-Ates F., et al.

BIOORGANIC & MEDICINAL CHEMISTRY , cilt.30, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

Determination of Tryptophan and Kynurenine by LC-MS/MS by Using Amlodipine as an Internal Standard

Eser B., ÖZKAN Y., SEPİCİ DİNÇEL A.

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY , cilt.31, sa.2, ss.379-385, 2020 (SCI-Expanded)

Microwave-assisted synthesis and pharmacological screening of some triazolothiadiazole derivatives

Gorgu O., YILDIRIM E., ÖZKAN Y., Cakir B., Erol K., ÖNKOL T.

BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES , cilt.56, 2020 (SCI-Expanded)

Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening

Ozgencil F., EREN G., ÖZKAN Y., GÜNTEKİN ERGÜN S., ATALAY R.

BIOORGANIC & MEDICINAL CHEMISTRY , cilt.28, sa.1, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors

Eren G., Bruno A., Guntekin-Ergun S., Atalay R., Ozgencil F., Özkan Y., et al.

JOURNAL OF MOLECULAR GRAPHICS & MODELLING , cilt.89, ss.60-73, 2019 (SCI-Expanded) Sürdürülebilir Kalkınma

Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents

Inceler N., ÖZKAN Y., Turan N. N., KAHRAMAN D. C., ATALAY R., BAYTAŞ S.

MEDCHEMCOMM , cilt.9, sa.5, ss.795-811, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Evaluation of Tryptophan/Kynurenine Pathway Relevance With Immune System Biomarkers of Low Energy Trauma Hip Fractures in Osteoporotic Patients

Dincel E., Özkan Y., Sukuroglu M. K., Ozsoy H., Sepici Dinçel A.

ARCHIVES OF RHEUMATOLOGY , cilt.32, sa.3, ss.203-208, 2017 (SCI-Expanded)

Synthesis and biological evaluation of some dibenzofuran-piperazine derivatives

YURTTAŞ L., Abu Mohsen U., ÖZKAN Y., Cobanoglu S., LEVENT S., KAPLANCIKLI Z. A.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY , cilt.31, sa.6, ss.1177-1183, 2016 (SCI-Expanded)

Relation of Kynurenine/Tryptophan with Immune and Inflammatory Markers in Coronary Artery Disease

Özkan Y., Şüküroğlu M. K., Tulmac M., Kısa Ü., Simsek B.

CLINICAL LABORATORY , cilt.60, sa.3, ss.391-396, 2014 (SCI-Expanded) Sürdürülebilir Kalkınma

Novel 1,3-diarylpyrazole acrylamides: synthesis, antiplatelet activity screening, and in silico evaluation studies

Baytaş S., Inceler N., Özkan Y., Unlu S., Sahin M. F.

MEDICINAL CHEMISTRY RESEARCH , cilt.22, sa.12, ss.5922-5933, 2013 (SCI-Expanded)

Serum homocysteine levels and sildenafil 50 mg response in young-adult male patients without vascular risk factors

Basar M. M., ÖZKAN Y., KISA Ü., Simsek B.

INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS , cilt.50, sa.3, ss.215-220, 2013 (SCI-Expanded)

Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation

Levent S., ÇALIŞKAN B., Ciftci M., ÖZKAN Y., Yenicesu I., ÜNVER H., et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , cilt.64, ss.42-53, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

Increased kynurenine tryptophan and neopterin levels in hemodialysis.

Hacışevki A., Baba B., Sezer S., Özkan Y.

Oxidation Communications , cilt.36, sa.1, ss.246-253, 2013 (SCI-Expanded)

The multidisciplinary approach to biochemistry laboratory education

Erkoc F., Sepici Dinçel A., Kayrin L., Özkan Y., Eksioglu S., Yüksel M., et al.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.38, sa.4, ss.506-512, 2013 (SCI-Expanded)

Variability of total thiol compounds, oxidative and nitrosative stress in uncomplicated pregnant women and nonpregnant women

Özkan Y., Yardim-Akaydin S., Erdem O. A., Simsek B.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS , cilt.285, sa.5, ss.1319-1324, 2012 (SCI-Expanded) Sürdürülebilir Kalkınma

Synthesis, anti-inflammatory, antiplatelet and in silico evaluations of (E)-3-(3-(2,3-dihydro-3-methyl-2-oxo-3H-benzoxazole-6-yl)-1-phenyl-1H-pyrazole-4-yl)acrylamides

BAYTAŞ S., Dural N. N. T., ÖZKAN Y., Simsek H. B., Gursel T., Unlu S.

TURKISH JOURNAL OF CHEMISTRY , cilt.36, sa.3, ss.367-382, 2012 (SCI-Expanded)

Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients

Özkan Y., Mete G., Sepici Dinçel A., Sepici V., Simsek B.

CLINICAL RHEUMATOLOGY , cilt.31, sa.1, ss.29-34, 2012 (SCI-Expanded)

Increased tryptophan degradation in patients with bronchus carcinoma

Engin A. B., ÖZKAN Y., Fuchs D., Yardim-Akaydin S.

EUROPEAN JOURNAL OF CANCER CARE , cilt.19, sa.6, ss.803-808, 2010 (SCI-Expanded) Sürdürülebilir Kalkınma

OXIDATIVE STATUS AND SERUM HOMOCYSTEINE LEVELS WITH CORONARY ARTERY STENOSIS

GÖNENÇ A., Irmak S., ÖZKAN Y., Sahingeri M., Korkmaz M. E.

IUBMB LIFE , cilt.61, sa.3, ss.328, 2009 (SCI-Expanded)

ROLE OF GLUCOCORTICOIDS DURING SEVOFLURANE ANAESTHESIA IN TOURNIQUET-INDUCED ISCHEMIA-REPERFUSION INJURY

Sepici-Dincel A., Ozkan Y., Izdes S., Gozdemir M., Kanbak O.

OXIDATION COMMUNICATIONS , cilt.32, sa.1, ss.226-235, 2009 (SCI-Expanded)

Circulating nitric oxide (NO), asymmetric dimethylarginine (ADMA), homocysteine, and oxidative status in obstructive sleep apnea-hypopnea syndrome (OSAHS)

Özkan Y., Firat H., Simsek B., Torun M., Yardim-Akaydin S.

SLEEP AND BREATHING , cilt.12, sa.2, ss.149-154, 2008 (SCI-Expanded) Sürdürülebilir Kalkınma

The effects of raloxifene and tibolone on homocysteine and vascular histopathological changes

Bayram M., Ozer G., Kalender H., Kabakci N., Kisa U., ÖZKAN Y.

CLINICAL AND EXPERIMENTAL MEDICINE , cilt.7, sa.4, ss.149-153, 2007 (SCI-Expanded)

The effect of general and regional anaesthesia on ischaemia-reperfusion injury

Izdes S., Sepici-Dincel A., Gozdemir M., ÖZKAN Y., Kanbak O.

ANAESTHESIA AND INTENSIVE CARE , cilt.35, sa.3, ss.451-452, 2007 (SCI-Expanded)

Usefulness of homocysteine as a cancer marker: Total thiol compounds and folate levels in untreated lung cancer patients

Özkan Y., Yardim-Akaydin S., Firat H., Caliskan-Can E., Ardic S., Simsek B.

ANTICANCER RESEARCH , cilt.27, sa.2, ss.1185-1189, 2007 (SCI-Expanded) Sürdürülebilir Kalkınma

Assessment of homocysteine, neopterin and nitric oxide levels in Behcet's disease

ÖZKAN Y., Yardim-Akaydin S., Sepici A., Engin B., Sepici V., Simsek B.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE , cilt.45, sa.1, ss.73-77, 2007 (SCI-Expanded)

Oxidative status in rheumatoid arthritis

ÖZKAN Y., Yardym-Akaydyn S., Sepici A., Keskin E., Sepici V., Simsek B.

CLINICAL RHEUMATOLOGY , cilt.26, sa.1, ss.64-68, 2007 (SCI-Expanded)

The association between total antioxidant status and oxidative stress in Behcet's disease

Sepici-Dincel A., ÖZKAN Y., Yardim-Akaydin S., Kaymak-Karatas G. K., Onder M., Simsek B.

RHEUMATOLOGY INTERNATIONAL , cilt.26, sa.11, ss.1005-1009, 2006 (SCI-Expanded)

Increased plasma homocysteine and allantoin levels in coronary artery disease: possible link between homocysteine and uric acid oxidation

ÖZKAN Y., Yardim-Akaydin S., Imren E., Torun M., Simsek B.

ACTA CARDIOLOGICA , cilt.61, sa.4, ss.432-439, 2006 (SCI-Expanded)

Evaluation of allantoin levels as a new marker of oxidative stress in Behcet's disease

Yardim-Akaydin S., Sepici A., ÖZKAN Y., Simsek B., Sepici V.

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY , cilt.35, sa.1, ss.61-64, 2006 (SCI-Expanded)

Prevalence of zinc deficiency and immune response in short-term hemodialysis

Bozalioglu S., ÖZKAN Y., Turan W., Simsek B.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY , cilt.18, sa.3, ss.243-249, 2005 (SCI-Expanded)

Oxidation of uric acid in rheumatoid arthritis: Is allantoin a marker of oxidative stress?

Yardim-Akaydin S., Sepici A., ÖZKAN Y., Torun M., Simsek B., Sepici V.

FREE RADICAL RESEARCH , cilt.38, sa.6, ss.623-628, 2004 (SCI-Expanded) Sürdürülebilir Kalkınma

The role of plasma thiol compounds and antioxidant vitamins in patients with cardiovascular diseases

Yardim-Akaydin S., Ozkan Y., Ozkan E., Torun M., Simsek B.

CLINICA CHIMICA ACTA , cilt.338, sa.1-2, ss.99-105, 2003 (SCI-Expanded) Sürdürülebilir Kalkınma

Plasma total homocysteine and cysteine levels as cardiovascular risk factors in coronary heart disease

Ozkan Y., Ozkan E., Simsek B.

INTERNATIONAL JOURNAL OF CARDIOLOGY , cilt.82, sa.3, ss.269-277, 2002 (SCI-Expanded) Sürdürülebilir Kalkınma

Plasma malondialdehyde (MDA) levels in breast and lung cancer patients

Gonenc A., Ozkan Y., Torun M., Simsek B.

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS , cilt.26, sa.2, ss.141-144, 2001 (SCI-Expanded) Sürdürülebilir Kalkınma

Diğer Dergilerde Yayınlanan Makaleler

Linker and tail group modifications on 2-((4-isopropyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-phenoxyphenyl)acetamide to improve SIRT2 inhibitory potency

GÖZELLE M., ÖZKAN Y., EREN G.

FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , cilt.49, sa.2, ss.317-332, 2024 (Scopus)

Homocysteine thiolactonase activity in coronary atherosclerosis

Altinay A., Kısa Ü., Tulmac M., Özkan Y.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE , cilt.11, sa.6, ss.634-638, 2020 (ESCI)

Neopterin: A possible biomarkers in gastrointestinal cancer

HACIŞEVKİ A., BABA B., aslan s., ÖZKAN Y.

Journal of Faculty of Pharmacy ankara , cilt.42, sa.2, ss.32-41, 2018 (Hakemli Dergi) Sürdürülebilir Kalkınma

Neopterin: A possible biomarker in gastrointestinal cancer

HACIŞEVKİ A., Baba B., Aslan S., ÖZKAN Y.

Ankara Universitesi Eczacilik Fakultesi Dergisi , cilt.42, sa.2, ss.32-41, 2018 (Scopus) Sürdürülebilir Kalkınma

Retinal Ganglion Cell Protection Via Topical and Systemic Alpha-Tocopherol Administration in Optic Nerve Crush Model of Rat

Aktaş Z., Özmen M. C., Uyar Göçün F. P., Değim Z., Özkan Y., Önol M.

TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY , cilt.43, sa.3, ss.161-166, 2013 (ESCI)

An Evaluation of Serum Retinol and Carotene Levels and the Risk of Breast Cancer

HACIŞEVKİ A., ÖZKAN Y., GÖNENÇ A., Şimşek B., TORUN F. M.

Journal of Faculty of Pharmacy of Gazi University , cilt.20, sa.2, ss.87-94, 2003 (Hakemli Dergi) Sürdürülebilir Kalkınma

Ascorbic acid and alpha tocopherol levels in breast cancer patients

HACIŞEVKİ A., ÖZKAN Y., Şimşek B., TORUN F. M.

Journal of faculty of Pharmacy of Gazi University , cilt.19, sa.2, ss.113-119, 2002 (Hakemli Dergi) Sürdürülebilir Kalkınma

Serum Vitamin E and Malondialdehyde levels in Cases with Head and Neck Cancer

ÖZKAN Y., Solak S., Şimşek B., TORUN F. M.

FABAD Journal of Pharmaceutical science , cilt.3, sa.23, ss.105-109, 1998 (Hakemli Dergi) Sürdürülebilir Kalkınma

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Ariloksiaril Asetamit Yapısında Sirtuin İnhibitörü Olabilecek Bileşiklerin Tasarımı, Sentezi ve Biyolojik Aktivite Çalışmaları

KAYA S. G., ÖZKAN Y., BAKAR ATEŞ F., ÖZKAN E., EREN G.

VII. Ulusal Farmasötik Kimya Kongresi, İzmir, Türkiye, 26 - 28 Ekim 2024

N-(5-(3-Methoxybenzyl)/(pyrimidin-2-yl-methyl))-1,3,4-oxadiazol-2-yl)-2-(arylthio)acetamide Derivatives as SIRT2 Inhibitors

AKSEL A. B., ÖZKAN Y., EREN G.

9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, Fransa, 8 - 09 Eylül 2022

In Silico Hit Optimization toward SIRT2 Inhibition: N-aryloxyaryl-2-(arylthio)acetamides

KAYA S. G., ÖZKAN Y., EREN G.

9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, Fransa, 8 - 09 Eylül 2022

Yeni Nikotinamit Fosforiboziltransferaz (NAMPT) İnhibitör Adaylarının Sanal Tarama Yöntemi ile Keşfi ve Biyolojik Etkilerinin Belirlenmesi

ÖZGENCİL F., ÖZKAN Y., EREN G.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022

Ariloksi Benzamit Yapısında Sirtuin İnhibitörü Olabilecek Bileşiklerin Tasarımı, Sentezi ve Biyolojik Aktivite Çalışmaları

YAĞCI S., GÖZELLE M., ÖZKAN Y., BAKAR ATEŞ F., EREN G.

VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022

IN SILICO HIT OPTIMIZATION TOWARD SIRT2 INHIBITION: N-ARYLOXYARYL-2-(ARYLTHIO)ACETAMIDES

KAYA S. G., ÖZKAN Y., EREN G.

EFMC-YMCS 9th Young Medicinal Chemists' Symposium, Nice, Fransa, 08 Eylül 2022

SIRT2 Inhibitory Activities of N-Aryloxyphenyl-2-(arylthio)acetamide Derivatives

KAYA S. G., ÖZKAN Y., EREN G.

GPSS-2021, 3rd International Gazi Pharma Symposium Series, Türkiye, 8 - 10 Eylül 2021

N-(5-Arylmethyl-1,3,4-oxadiazole-2-yl)-2-(arylthio)acetamide as a New Scaffold for Developing Small-molecule SIRT Inhibitors

AKSEL A. B., ÖZKAN Y., EREN G.

GPSS-2021, 3rd International Gazi Pharma Symposium Series, Türkiye, 8 - 10 Eylül 2021

Discovery of 5-Benzyl-1,3,4-oxadiazole/thiadiazole-2-carboxamides as Potential Leads for Selective SIRT2 Inhibition

GÖZELLE M., ÖZKAN Y., EREN G.

GPSS-2021, 3rd International Gazi Pharma Symposium Series, Ankara, Türkiye, 8 - 10 Eylül 2021

Determination of tryptophan and kynurenine by LC-MS/MS by using amilodipine as internal standard

Eser B., ÖZKAN Y., SEPİCİ DİNÇEL A.

XXVII. Balkan Clinical Laboratory Federation Meeting BCLF 2019, Antalya, Türkiye, 27 - 31 Ekim 2019, cilt.44, ss.69

Virtual Screening to Discover Drug Candidates Targeting Platelet Receptors

OLĞAÇ S., OLĞAÇ A., YENİCESU İ., ÖZKAN Y.

Asian Federation of Medicinal Chemistry (AFMC) 12th International Symposium, İstanbul, Türkiye, 8 - 11 Eylül 2019

Antiplatelet aggregation of the secondary metabolites isolated from the aerial parts of Chrysophthalmum montanum (DC.) Boiss.

AYAZ F., ÖZKAN Y., OLĞAÇ S., GÖREN N., ÇALIŞ İ., Choudhary M. I., et al.

2nd International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2019), 28 - 29 Haziran 2019

Indolamine 2 3 dioxygenase related metabolic effects of 3 aminobenzamide and infliximab in lung tissue of experimental colitis model

ŞAHİN D., SEPİCİ DİNÇEL A., AKCA G., ÖZKAN Y., MENEKŞE E., DOLAPÇI M.

40th FEBS Congress, 4 - 09 Temmuz 2015, cilt.282, ss.279

Metrikler

Yayın

Atıf (WoS)

878

H-İndeks (WoS)

Atıf (Scopus)

978

H-İndeks (Scopus)

Atıf (Scholar)

985

H-İndeks (Scholar)

Atıf (TrDizin)

H-İndeks (TrDizin)

Proje

Tez Danışmanlığı

Açık Erişim

BM Sürdürülebilir Kalkınma Amaçları

Yayınlar & Eserler

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Diğer Dergilerde Yayınlanan Makaleler

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Kitap & Kitap Bölümleri

Metrikler

Yayın

Atıf (WoS)

H-İndeks (WoS)

Atıf (Scopus)

H-İndeks (Scopus)

Atıf (Scholar)

H-İndeks (Scholar)

Atıf (TrDizin)

H-İndeks (TrDizin)

Proje

Tez Danışmanlığı

Açık Erişim