SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler
Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.33, sa.1, ss.1352-1361, 2018 (SCI-Expanded)
Screening and evaluation of antioxidant activity of some pyridazine derivatives
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.23, sa.2, ss.225-229, 2008 (SCI-Expanded)
Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
, cilt.27, sa.2, ss.135-140, 2002 (SCI-Expanded)
Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
, cilt.26, sa.4, ss.235-240, 2001 (SCI-Expanded)
Diğer Dergilerde Yayınlanan Makaleler
Crystal structure and Hirshfeld surface analysis of methyl 1-(2,4-dichlorobenzyl)-5-methyl-1H-pyrazole-3-carboxylate
European Journal of Chemistry
, cilt.9, sa.4, ss.347-352, 2018 (Hakemli Dergi)
Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar
Unveiling Novel Leukotriene B4 Receptor (BLT1R) Antagonists and Their Binding Characteristics Through Combined Strategies
Gordon Research Conference on Computer Aided Drug Design, Vermont, Amerika Birleşik Devletleri, 16 - 21 Temmuz 2023
A Tale of Two 5-Lipoxygenase Activating Protein (FLAP) Inhibitors
Gordon Research Seminar on Computer Aided Drug Design, Vermont, Amerika Birleşik Devletleri, 15 - 16 Temmuz 2023
A journey from selective FLAP inhibitor to selective mPGES-1 inhibitor: A new therapeutic modality for reducing inflammation and pain
8th International Bahçeşehir University (BAU) Drug Design Congress, İstanbul, Türkiye, 15 - 17 Aralık 2022
Identification of Novel Microsomal Prostaglandin E2 Type 1 (mPGES-1) Inhibitors by Conducting Structure-based Virtual Screening
International Bioinformatics Conference (IBC 2022), Tanjah, Fas, 8 - 09 Ekim 2022, ss.17
Novel Microsomal Prostaglandin E2 Synthase-1 (MPGES-1) Inhibitors as a New Modality To Treat Inflammation
XXVll EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2022), Nice, Fransa, 4 - 08 Eylül 2022
Evaluation of Oxadiazole Derivatives as Promising Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors
XXVll EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC 2022), Nice, Fransa, 4 - 08 Eylül 2022
NOVEL BENZOTHIAZOLE DERIVATIVESAS MICROSOMAL PROSTAGLANDINE E2SYNTHASE-1 (mPGES-1) INHIBITORS
9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, Fransa, 8 - 09 Eylül 2022
KARACİĞER KANSERİ KÖK HÜCRELERİ ÜZERİNDE İNHİBİTÖR ETKİYE SAHİP, POTANSİYEL ANTİKANSER AJANLAR OLARAK YENİ İZOKSAZOL-PİPERAZİN HİBRİTLERİNİN SENTEZİ VE BİYOLOJİK OLARAK DEĞERLENDİRİLMESİ
VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022
Bazı Visinal Diaril Heterosiklik Bileşiklerin Antikanser Aktivitelerinin Araştırılması
VI.Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 - 29 Ağustos 2022, ss.42-44
TACC3 İnhı̇bı̇törü Yenı̇ 2,4-Dı̇amı̇nopı̇rı̇mı̇dı̇n Türevlerı̇nı̇n Sentezı̇, Antı̇-Kanser Etkı̇ Potansı̇yellerı̇ ve İlaç Benzerı̇ Özellı̇klerı̇nı̇n Değerlendı̇rı̇lmesı̇ Üzerı̇ne Çalışmalar
VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Türkiye, 26 Ağustos 2022
SELECTIVE OR DUAL INHIBITORS OF INFLAMMATORY PGE2 AND LTB4 BIOSYNTHESIS BY TARGETING mPGES-1 AND FLAP TO INTERVENE WITH INFLAMMATORY DEREGULATION
The Sixth International Symposium on Pharmaceutical and Biomedical Sciences (ISPBS-6), Gaziantep, Türkiye, 26 - 28 Mayıs 2022
Discovery of Novel Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors: A New Modality to Treat Inflammation
10th International Drug Chemistry Conference, Antalya, Türkiye, 10 - 13 Mart 2022
Synthesis of 3,4-Diaryl-5-methylisoxazoles with Potent Antiproliferative Activity Against a Panel of Human Liver and Breast Cancer Cell Lines
EFMC-ISMC EFMC-YMCS Virtual Poster Session, 09 Eylül 2020
Vicinal Diaryl Heterocyclic Compounds with Potential Anticancer Activity
EFMC-ISMC EFMC-YMCS Virtual Poster Session, 09 Eylül 2020
Synthesis of New Vicinal Diaryl Five-Membered Heterocyclic Compounds with Potential Anticancer Activity
8th International Drug Chemistry Conference, 27 Şubat - 01 Mart 2020
Discovery of Multitarget Inhibitors in the Arachidonic Acid Pathway by Targeting FLAP/5-LO/mPGES-1 for Intervention with Inflammatory Deregulation
8th International Drug Chemistry Conference, Antalya, Türkiye, 27 Şubat - 01 Mart 2020
A SMALL MOLECULE INHIBITOR OF TRANSFORMING ACIDICCOILED-COIL PROTEIN 3 (TACC3): A NOVEL THERAPEUTICSTRATEGY FOR THE TREATMENT OF BREAST CANCER
11th Joint Meeting on Medicinal Chemistry 2019, PRAG, Çek Cumhuriyeti, 27 - 30 Haziran 2019
A Novel TACC3 inhibitor as an anti-cancer agent in breast cancer
30th EORTC-NCI-AACR Symposium, Dublin, İrlanda, 13 - 16 Kasım 2018
DISCOVERY OF NOVEL 5-LIPOXYGENASE ACTIVATING PROTEIN (FLAP) INHIBITORS BY VIRTUAL SCREENING ANDPHARMACOLOGICAL EVALUATION
22nd European Symposium on Quantitative Structure-Activity RelationshipsTranslational and Health Informatics: Implications for Drug Discovery, 16 - 20 Eylül 2018
EVOLUTION OF SELECTIVE FLAP INHIBITOR BRP-7 INTO MULTI-TARGET INHIBITOR OF FLAP, 5-LO AND MPGES-1 IN THE ARACHIDONIC ACID PATHWAY
EFMC International Symposium on Medicinal Chemistry, Ljubljana, Slovenya, 2 - 06 Eylül 2018, ss.231
SYNTHESIS AND ANTIPROLIFERATIVE EVALUATION OF NOVEL ISOXAZOLE-PIPERAZINE HYBRIDS
RICT 2018, 4 - 06 Temmuz 2018
PROTEIN-LIGAND INTERACTION ANALYSIS THROUGH DOCKING AND MOLECULAR DYNAMIC SIMULATIONS OF KNOWN 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS
RICT 2018 Interfacing Chemical Biology and Drug Discovery 54th International Conference on Medicinal Chemistry, Strasbourg, Fransa, 4 - 06 Temmuz 2018
ANTİLÖKOTRİEN ETKİLİ 1,2,5-TRİSÜBSTİTÜEBENZİMİDAZOL TÜREVLERİNİN GELİŞTİRİLMESİ ÜZERİNDE YAPILAN ÇALIŞMALAR
V. ULUSAL FARMASÖTİK KİMYA KONGRESİ, Erzurum, Türkiye, 28 Nisan - 01 Mayıs 2018
SANAL TARAMA VE FARMAKOLOJİK DEĞERLENDİRME YOLUYLA YENİ 5-LİPOKSİJENAZ AKTİVE EDİCİ PROTEİN (FLAP) İNHİBİTÖRÜ BİLEŞİKLERİN KEŞFİ
V. ULUSAL FARMASÖTİK KİMYA KONGRESİ, Erzurum, Türkiye, 28 Nisan - 01 Mayıs 2018
Discovery of Tyrosinase Inhibitors from Geranium glaberrimum Boiss. Heldr. Using In Vitro and In Silico Methods
The 4th Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-2018), 18 - 22 Nisan 2018
Discovery and Development of Novel Anti-cancer and Anti-inflammatory Compounds: Medicinal Chemistry Challenges
The 4th International Symposium on Pharmaceutical and Biomedical Sciences, Kumamoto, Japonya, 17 Mart 2018
Discovery of Novel 5-Lipoxygenase Activating Protein (FLAP) Inhibitors by Virtual Screening
2nd International Gazi Pharma Symposium Series, 11 - 13 Ekim 2017
FROM BATCH TO CONTINUOUS FLOW CHEMISTRY:DOE-ASSISTED OPTIMIZATION OF BENZIMIDAZOL-2-ONESYNTHESIS
2nd International Gazi Pharma Symposium Series, 11 - 13 Ekim 2017
Developing Multi-target Inhibitors of Arachidonic Acid Pathway Based on the FLAP Inhibitor BRP-7
2nd International Gazi Pharma Symposium Series, 11 - 13 Ekim 2017
Discovery of Dual FLAP/mPGES-1 Inhibitors for Intervention with Inflammatory Diseases:Medicinal Chemistry Challenges
Turkish Japanese Workshop on Bioorganic Medicinal Chemistry Natural Products, 14 Eylül 2017
Tirozinaz İnhibitör Etkili Yeni Sinnamik Asit Türevleri
29. Ulusal Kimya Kongresi, Türkiye, 10 - 14 Eylül 2017, ss.452
Discovery of Novel 5-Lipoxygenase Activating Protein (FLAP) Inhibitors by Combined Ligand- and Structure-Based Virtual Screening
EFMC-ASMC’xx17 EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, 27 - 31 Ağustos 2017
Bioisosteric Tuning of FLAP Inhibitor BRP-7 Towards a More Potent Antiinmlammatory Agent with Multiligand Inhibitor Properties in the Arachidonic Acid (AA) Pathway
EFMC-ASMC’xx17 EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry, 27 - 31 Ağustos 2017
Discovery of Novel Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors Using Structure-Based Virtual Screening.
EFMC-ASMC 2017 International Symposium on Advances in Synthetic and Medicinal Chemistry, 27 - 31 Ağustos 2017
Araşidonik asit yolağında çoklu ligand (FLAP/5-LO/mPGES-1) özellikte inhibitör etkili BRP-7 türevlerinin geliştirilmesi
1. Anadolu Üniversitesi Eczacılık Sempozyumu, Eskişehir, Türkiye, 1 - 02 Haziran 2017, ss.10
Diarilpirazol Türevi Bileşiğin (BRP-42) Analjezik ve Antienflamatuvar Aktivitesi Üzerinde Çalışmalar
3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.752
İzoksazol Türevi Bileşiklerin in-vivo Analjezik ve Antienflamatuvar Aktivitesi Üzerinde Çalışmalar
3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.738
5-Sübstitüe-Benzimidazol Türevi Bileşiğin Farelerde Analjezik ve Antienflamatuvar Aktivite Tarama Çalışması
3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 - 29 Nisan 2017, ss.732
Structure Guided Design of Novel Isoxazole and Benzimidazole Derivatives as Potent 5 Lipoxygenase 5 LO and 5 LO Activating Protein FLAP Inhibitors
XXIV National Meeting in Medicinal Chemistry, Perugia, İtalya, 11 - 14 Eylül 2016
Evias Web Services Cloud Based Drug Discovery Platform
21st European Symposium on Quantitative Structure-Activity Relationship, Verona, İtalya, 4 - 08 Eylül 2016
Novel BRP 7 Derivatives Targeting FLAP Potent Inhibitors of Leukotriene Biosynthesis
3rd EFMC Young Medicinal Chemist Symposium, Manchester, Birleşik Krallık, 1 - 02 Eylül 2016
EXPLORATION OF THE CHEMICAL SPACE AROUND C 5 POSITION OF THE BENZIMIDAZOLE NUCLEUS IN BRP 7 TOWARDS MORE POTENT INHIBITORS OF HUMAN 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP
EFMC International Symposium on Medicinal Chemistry, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016
DISCOVERY OF 4 5 DIARYLISOXAZOL 3 CARBOXYLIC ACID SKELETON AS A NOVEL CHEMOTYPE FOR INHIBITION OF 5 LIPOXYGENASE ACTIVATING PROTEIN FLAP
EFMC International Symposium on Medicinal Chemistry, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016
Discovery of 4 5 Diarylisoxazol 3 Carboxylic Acid Skeleton as a Novel Chemotype for Inhibition of 5 Lipoxygenase Activating Proteın FLAP
EFMC International Symposium on Medicinal Chemistry 2016, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016
Exploratıon of the Chemıcal Space Around C 5 Posıtıon Of The Benzimidazole Nucleus in BRP 7 Towards More Potent Inhıbıtors of Human 5 Lıpoxygenase Actıvatıng Proteın FLAP
EFMC International Symposium on Medicinal Chemistry 2016, Manchester, Birleşik Krallık, 28 Ağustos - 01 Eylül 2016
Structure Guided Design of Novel Isoxazole and Benzimidazole Derivatives as Potent FLAP and 5 LO Inhibitors
IBSS'2016 Resources and Techniques in Computational Drug Discovery, Fas, 23 - 26 Mayıs 2016
Evias Cloud Based Drug Discovery Platform
High-Performance Modelling and Simulation for Big Data Applications - Management Committee & Working Group Meeting, Dublin, İrlanda, 25 - 26 Nisan 2016
İzole Sfenoid Sinüs Cerrahisi 40 vakalık serimiz
37. ULUSAL KBB BBC KONGRESİ, Türkiye, 28 Ekim - 01 Kasım 2015
Structure-Based Design And Synthesis Of Novel Isoxazole And Benzimidazole Derivatives As Potent FLAP and 5-LO Inhibitors: Insights From Molecular Dynamics Simulations
Summer School on Drug Design in September in Vienna 2015, Viyana, Avusturya, 20 - 25 Eylül 2015
Structure-Based Design and Synthesis of Novel BRP-7 Derivatives as Potent FLAP Inhibitors: Insights from MolecularDynamics Simulations.
EFMC International Symposium on Medicinal Chemistry, LİZBON, Portekiz, 7 - 11 Eylül 2014, ss.162
Towards Pharmacophore and Docking based Virtual Screening of Human P2Y12 Receptor Antagonists with the Homology modeled Protein Structure
20th EuroQSAR, Understanding Chemical-Biological Interactions, St. Petersburg, Rusya, 31 Ağustos - 04 Eylül 2014
Computer Aided Drug Design Targeting 5LO and FLAP
The First Technical Meeting on High-Throughput Molecular Dynamics 2013, 7 - 08 Kasım 2013
New 4,5-Diarylisoxazole Derivatives as Novel Inhibitors of Human 5-Lipoxygenase (5-LO)
EFMC-ISMC 2012, XXIInd International Symposium on Medicinal Chemistry, Berlin, Almanya, 2 - 06 Eylül 2012
From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors
EFMC-ISMC 2012, XXIInd International Symposium on Medicinal Chemistry, Berlin, Almanya, 2 - 06 Eylül 2012
New Isoxazole Derivatives as Novel Inhibitors of 5-Lipoxygenase
4th International Symposium on Advanced in Synthetic and Medicinal Chemistry, St. Petersburg, Rusya, 21 - 25 Ağustos 2011
From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors
VIII EWDD, Eighth European Workshop in Drug Design, Siena, İtalya, 22 - 28 Mayıs 2011
An Approach to Combined Ligand- and Structure-Based Virtual Screening and QSAR Studies for Determining Novel 5-Lipoxygenase Inhibitors
IMMPC-ISPC Joint Meeting, 4th International Meeting on Medicinal and Pharmaceutical Chemistry, 6th International Symposium on Pharmaceutical Chemistry, Ankara, Türkiye, 30 Eylül - 02 Ekim 2010
Studies on Synthesis and In Vitro Cyclooxygenase Inhibitory Activities of Diaryl Heterocyclic Compounds
EFMC-ISMC 2010, XXIst International Symposium on Medicinal Chemistry, Brüksel, Belçika, 5 - 09 Eylül 2010
Combining of Ligand- and Structure-Based Information to Derive a Pharmacophore Model for Determining Novel FLAP Inhibitors
Vienna Summer School on Drug Design, Viyena, Avusturya, 13 - 18 Eylül 2009
Homology Modeling of Human 5-Lipoxygenase and Molecular Docking Simulations of Competitive Inhibitors
3rd International Meeting on Medicinal and Pharmaceutical Chemistry, IMMPC-3, Antalya, Türkiye, 16 - 21 Ekim 2007
Synthesis of 2-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]acetmide and 3-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]propanamide Derivatives as analgesic and anti-inflammatory agents
XIXth International Symposium on Medicinal Chemistry, İstanbul, Türkiye, 29 Ağustos - 02 Eylül 2006
Synthesis, Characterizaton and Preliminary Screening of Regioisomeric 1-(3-Pyridazinyl)-3-arylpyrazole and 1-(3-Pyridazinyl)-5-arylpyrazole Derivatives Towards Cyclooxygenase Inhibition
XIXth International Symposium on Medicinal Chemistry, ISMC 2006, İstanbul, Türkiye, 29 Ağustos - 02 Eylül 2006