Prof. GÖKÇEN EREN


Eczacılık Fakültesi, Eczacılık Meslek Bilimleri

Farmasötik Kimya


WoS Research Areas: Natural Sciences (Sci), Life Sciences (Life)


Avesis Research Areas: Health Sciences, Pharmacology and Therapeutics

Metrics

Publication

88

Citation (WoS)

729

H-Index (WoS)

12

Citation (Scopus)

786

H-Index (Scopus)

14

Project

23

Intellectual Property

1

Thesis Advisory

3

Open Access

5
UN Sustainable Development Goals

Education

2003 - 2008

2003 - 2008

Doctorate

Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Dr), Turkey

2000 - 2003

2000 - 2003

Postgraduate

Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Yl) (Tezli), Turkey

1996 - 2000

1996 - 2000

Undergraduate

Gazi University, Eczacılık Fakültesi, Eczacılık Pr., Turkey

Dissertations

2008

2008

Doctorate

Diaril heterosiklik yapıda siklooksijenaz inhibitörü olabilecek bileşiklerin sentezi ve in vitro inhibitör etki tayinleri üzerinde çalışmalar

Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Dr)

2003

2003

Postgraduate

Bazı benzimidazol türevlerinin platin(II) komplekslerinin sentez ve in vitro antitümör üzerinde çalışmalar

Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Yl) (Tezli)

Foreign Languages

C2 Mastery

C2 Mastery

English

Research Areas

Health Sciences

Pharmacology and Therapeutics

Academic Positions

2019 - Continues

2019 - Continues

Professor

Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri

2017 - 2019

2017 - 2019

Associate Professor

Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri

2002 - 2017

2002 - 2017

Research Assistant

Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri

Managerial Experience

2018 - 2021

2018 - 2021

Vice Dean

Gazi University, Eczacılık Fakültesi

Non Academic Experience

2016 - 2016

2016 - 2016

Konuk Araştırmacı

Dipartimento di Farmacia, Università di Parma, Italia, Konuk Araştırmacı

2007 - 2007

2007 - 2007

Konuk Araştırmacı

Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Italia, Konuk Araştırmacı

Courses

Doctorate

Doctorate

MOLEKÜLER MODELLEME TEKNİKLERİ

ORGANİK REAKSİYON MEKANİZMALARI II

Postgraduate

Postgraduate

İLAÇ TASARIMI

ORGANİK REAKSİYON MEKANİZMALARI I

Undergraduate

Undergraduate

FARMASÖTİK KİMYA IV UYGULAMA

FARMASÖTİK KİMYA II

BİLGİSAYAR DESTEKLİ İLAÇ TASARIMI

Journal articles indexed in SCI, SSCI, and AHCI

Papers Presented at Peer-Reviewed Scientific Conferences

2024

2024

Virtual Screening using Structure-based Pharmacophore to Identify Novel NAPRT Inhibitors

GÜNİNDİ H. B., MASSAROTTI A., EREN G.

24th European Symposium on Quantitative Structure-Activity Relationship, Barselona, Spain, 22 - 26 September 2024, (Summary Text)

2024

2024

DEVELOPING A FIELD-BASED 3D-QSAR MODEL THROUGH SIRT2INHIBITORY PROFILES OF IN-HOUSE COMPOUNDS

Özgencil F., Eren G.

24th European Symposium on Quantitative Structure-Activity Relationship 24th European ip, Barcelona, Spain, 22 - 26 September 2024, (Summary Text)

2024

2024

Phytochemical and Activity Studies on Geranium Subcaulescens

Özüpek B., Şöhretoğlu D., Sˇoral M., Özgencil F., Eren G., Deliorman Orhan D.

International Congress on Integrative Medicine and Health, Ohio, United States Of America, 11 - 13 April 2024, pp.54-55, (Summary Text)

2023

2023

Screening of Some Plant-Derived Compounds Against Enzymes Associated With Alzheimer's Disease By In Vitro and In Silico Method

Şenol Deniz F. S., Eren G., Erdoğan Orhan İ.

9th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-9), Ankara, Turkey, 3 - 05 May 2023, pp.1, (Summary Text)

2022

2022

3D-QSAR Studies on Amide and Urea Derivatives as NAMPT Inhibitors

ÖZGENCİL F., EREN G.

9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022, (Summary Text)

2022

2022

In Silico Hit Optimization toward SIRT2 Inhibition: N-aryloxyaryl-2-(arylthio)acetamides

KAYA S. G., ÖZKAN Y., EREN G.

9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022, (Summary Text)

2022

2022

N-(5-(3-Methoxybenzyl)/(pyrimidin-2-yl-methyl))-1,3,4-oxadiazol-2-yl)-2-(arylthio)acetamide Derivatives as SIRT2 Inhibitors

AKSEL A. B., ÖZKAN Y., EREN G.

9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022, (Summary Text)

2023

2023

Electrochemical, Spectrofluorimetric & Molecular Docking Approaches to Evaluate the Interaction of Cinacalcet HCl with Calf-Thymus dsDNA

Ünal D. N., ERKMEN C., KURBANOĞLU S., EREN G., USLU B.

33rd International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2023), Ankara, Turkey, 2 - 06 July 2023, (Summary Text)

2021

2021

SIRT2 Inhibitory Activities of N-Aryloxyphenyl-2-(arylthio)acetamide Derivatives

KAYA S. G., ÖZKAN Y., EREN G.

GPSS-2021, 3rd International Gazi Pharma Symposium Series, Turkey, 8 - 10 September 2021, (Summary Text)

2021

2021

N-(5-Arylmethyl-1,3,4-oxadiazole-2-yl)-2-(arylthio)acetamide as a New Scaffold for Developing Small-molecule SIRT Inhibitors

AKSEL A. B., ÖZKAN Y., EREN G.

GPSS-2021, 3rd International Gazi Pharma Symposium Series, Turkey, 8 - 10 September 2021, (Summary Text)

2021

2021

Discovery of 5-Benzyl-1,3,4-oxadiazole/thiadiazole-2-carboxamides as Potential Leads for Selective SIRT2 Inhibition

GÖZELLE M., ÖZKAN Y., EREN G.

GPSS-2021, 3rd International Gazi Pharma Symposium Series, Ankara, Turkey, 8 - 10 September 2021, (Summary Text)

2021

2021

Investigation of Interaction Between Milrinone and DNA by Electrochemical, Spectroscopic and Molecular Docking Study

USLU B., ÜNAL D. N., ERKMEN C., SELÇUK Ö., EREN G., KURBANOĞLU S.

PBA2021, International Symposium on Pharmaceutical and Biomedical Analysis, Kyoto, Japan, 29 August - 01 September 2021, (Summary Text)

2019

2019

Novel Pyridazinone Derivatives as Selective Butrylcholinesterase Inhibitors

DÜNDAR Y., KUYRUKÇU Ö., EREN G., ŞENOL DENİZ F. S., ERDOĞAN ORHAN İ.

EFMC- YMCS, 6th EFMC Young Medicinal Chemist Symposium, 5 - 06 September 2019, (Summary Text)

2019

2019

Design and Synthesis of Aryloxy Benzamide Derivatives with Potential Inhibitory Effect against SIRT2

YAGCI S., GÖZELLE M., KAYA S. G., EREN G.

EFMC-YMCS, 6th EFMC Young Medicinal Chemist Symposium, 5 - 06 September 2019, (Summary Text)

2016

2016

Pharmacophore Based Virtual Screening to Identify Novel SIRT2 Inhibitors

EREN G., BRUNO A., COSTANTINO G.

21st EuroQSAR, Where Molecular Simulations Meet Drug Discovery, 4 - 08 October 2016, (Summary Text)

2014

2014

Towards Pharmacophore and Docking based Virtual Screening of Human P2Y12 Receptor Antagonists with the Homology modeled Protein Structure

EREN G., BANOĞLU E.

20th EuroQSAR, Understanding Chemical-Biological Interactions, St. Petersburg, Russia, 31 August - 04 September 2014, (Summary Text)

2012

2012

From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors

EREN G., MACCHIARULO A., BANOĞLU E.

EFMC-ISMC 2012, XXIInd International Symposium on Medicinal Chemistry, Berlin, Germany, 2 - 06 September 2012, (Summary Text)

2012

2012

New 4,5-Diarylisoxazole Derivatives as Novel Inhibitors of Human 5-Lipoxygenase (5-LO)

ÇALIŞKAN B., LUDERER S., GERSTMEIER J., EREN G., WERZ O., BANOĞLU E.

EFMC-ISMC 2012, XXIInd International Symposium on Medicinal Chemistry, Berlin, Germany, 2 - 06 September 2012, (Summary Text)

2011

2011

New Isoxazole Derivatives as Novel Inhibitors of 5-Lipoxygenase

ÇALIŞKAN B., LUDERER S., EREN G., WERZ O., BANOĞLU E.

4th International Symposium on Advanced in Synthetic and Medicinal Chemistry, St. Petersburg, Russia, 21 - 25 August 2011, (Summary Text)

2010

2010

An Approach to Combined Ligand- and Structure-Based Virtual Screening and QSAR Studies for Determining Novel 5-Lipoxygenase Inhibitors

EREN G., BANOĞLU E.

IMMPC-ISPC Joint Meeting, 4th International Meeting on Medicinal and Pharmaceutical Chemistry, 6th International Symposium on Pharmaceutical Chemistry, Ankara, Turkey, 30 September - 02 October 2010, (Summary Text)

2010

2010

Studies on Synthesis and In Vitro Cyclooxygenase Inhibitory Activities of Diaryl Heterocyclic Compounds

EREN G., ÜNLÜ S., NUNEZ M. T., LABEAGA L., ENTRENA A., BANOĞLU E., et al.

EFMC-ISMC 2010, XXIst International Symposium on Medicinal Chemistry, Brüksel, Belgium, 5 - 09 September 2010, (Summary Text)

2009

2009

Diaril Heterosiklik Yapıda Siklooksijenaz İnhibitörü Olabilecek Bileşiklerin Sentezi ve İn Vitro İnhibitör Etki Tayinleri Üzerinde Çalışmalar

Eren G.

II. Ulusal Farmasötik Kimya Kongresi, Mersin, Turkey, 13 - 15 November 2009, pp.1-2, (Summary Text)

2009

2009

Synthesis and Cytotoxicity of New Cisplatin Analogues Containing Substituted Benzimidazole Ligands

EREN G., GÜMÜŞ F., GÜR S., ÖZKUL A.

3rd International Symposium on Advances in Synthetic and Medicinal Chemistry, Kiev, Ukraine, 23 - 27 August 2009, (Summary Text)

2007

2007

Homology Modeling of Human 5-Lipoxygenase and Molecular Docking Simulations of Competitive Inhibitors

EREN G., ÇALIŞKAN B., COSTANTINO G., MACCHIARULO A., ÜNLÜ S., ÇAKIR B., et al.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, IMMPC-3, Antalya, Turkey, 16 - 21 October 2007, (Summary Text)

2006

2006

Bazı Benzimidazol Türevlerinin Platin II Komplekslerinin Sentezi ve İn Vitro Antitümör Aktiviteleri Üzerinde Çalışmalar

EREN G., GÜMÜŞ F.

I. Ulusal Farmasötik Kimya Kongresi, İstanbul, Turkey, 11 - 13 November 2006, (Summary Text)

2006

2006

Studies on synthesis and in vitro COX inhibitory activities of diaryl heterocyclic compounds

EREN G.

European Network of Doctoral Studies in Pharmaceutical Sciences, 3rd Annual Meeting, Catania, Italy, 03 November 2006, (Summary Text)

2003

2003

Mutagenic and Antimutagenic Activities of Platinum(II) Complexes with 2-Substituted Benzimidazole Ligands

EREN G., ALGÜL Ö., GÜMÜŞ F., EROĞLU H., DİRİL N.

4th International Symposium on Pharmaceutical Chemistry, ISPC-4, İstanbul, Turkey, 17 - 19 September 2003, (Summary Text)

2003

2003

Cytotoxic Activity of Platinum(II) Complexes with 2-Substituted Benzimidazole Ligands on MCF-7 Cell Line

ALGÜL Ö., EREN G., GÜMÜŞ F., GÜR S., ÖZKUL A.

International Symposium on Pharmaceutical Science, ISOPS-7, Ankara, Turkey, 24 - 27 June 2003, (Summary Text)

Books

2021

2021

Kantitatif Yapı Etki İlişkileri [QSAR]

Eren G.

in: Medisinal Kimya, Alp Mehmet, Editor, Akademisyen Yayınevi, Ankara, pp.846-864, 2021

2018

2018

Türk Farmakopesi

TUNÇBİLEK M., YEŞİLADA A., BALKAN A., TOZKOPARAN B., PALASKA E., ÖZKANLI F., et al.

T. C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu, Ankara, 2018

Funded Projects

2022 - 2024

2022 - 2024

Yeni 2,7-Disübstitüe 9H-Fluoren-9-on Türevleri: Tasarımı, Sentezi ve SIRT2 İnhibitör Etkilerinin Araştırılması

Research Project of the Presidency of Turkey Health Institutes (TÜSEB)

Kaya S. G., Eren G. (Executive), Özkan Y.

2018 - 2019

2018 - 2019

Yeni NAMPT İnhibitörlerinin Sanal Tarama Yöntemi ile Keşfi

TUBITAK Project

Eren G. (Executive)

2012 - 2015

2012 - 2015

Sübstitüe Benzimidazol Ligandı Taşıyan Yeni Trans-Platin(II) Komplekslerinin Sentezi ve Karakterizasyonu

Project Supported by Higher Education Institutions

EREN G. (Executive)

2012 - 2015

2012 - 2015

Sübstitüe Benzimidazol Ligandı Taşıyan Yeni Trans Platin II Komplekslerinin Sentezi ve Karakterizasyonu

Project Supported by Higher Education Institutions

Eren G. (Executive), Gümüş F.

2011 - 2014

2011 - 2014

5-Lipoksijenaz (5-LO) İnhibitörü Olabilecek Yeni Bileşiklerin Sentezi ve Moleküler  Modelleme Çalışmaları

Project Supported by Higher Education Institutions

EREN G. (Executive)

2011 - 2014

2011 - 2014

5 Lipoksijenaz 5 LO İnhibitörü Olabilecek Yeni Bileşiklerin Sentezi ve Moleküler Modelleme Çalışmaları

Project Supported by Higher Education Institutions

EREN G. (Executive)

2010 - 2012

2010 - 2012

5-Lipoksijenaz İnhibitör Etkili Yeni Moleküllerin Moleküler Modelleme Çalışmaları ile Tasarımı

Project Supported by Higher Education Institutions

EREN G. (Executive)

Patent

2016

2016

LÖKOTRİEN BİYOSENTEZ İNHİBİTÖRLERİ OLARAK İZOKSAZOL TÜREVLERİ

Patent

Registered / Approved, The Invention Registration Number: 2014 05943 , Standard Registration

Memberships and Roles in Scientific Organizations

2019 - Continues

2019 - Continues

Organisation for Women in Science for the Developing World (OWSD) Turkey National Chapter Sustainable Development

Board Member

2017 - 2021

2017 - 2021

Türk Farmasötik ve Medisinal Kimya Derneği

Board Member

Awards

April 2011

April 2011

2009-2010 Novartis Farmasötik ve Medisinal Kimya İlaç Tasarım ve Geliştirme Araştırma Birincilik Ödülü

Novartis



Citations

Total Citations (WOS): 688

h-index (WOS): 12