Metrics
Publication
90
Open Access
6
UN Sustainable Development Goals
Education
2003 - 2008
2003 - 2008Doctorate
Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Dr), Turkey
2000 - 2003
2000 - 2003Postgraduate
Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Yl) (Tezli), Turkey
1996 - 2000
1996 - 2000Undergraduate
Gazi University, Eczacılık Fakültesi, Eczacılık Pr., Turkey
Dissertations
2008
2008Doctorate
Diaril heterosiklik yapıda siklooksijenaz inhibitörü olabilecek bileşiklerin sentezi ve in vitro inhibitör etki tayinleri üzerinde çalışmalar
Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Dr)
2003
2003Postgraduate
Bazı benzimidazol türevlerinin platin(II) komplekslerinin sentez ve in vitro antitümör üzerinde çalışmalar
Gazi University, Sağlık Bilimleri Enstitüsü, Farmasotik Kimya (Yl) (Tezli)
Foreign Languages
C2 Mastery
C2 MasteryEnglish
Research Areas
Health Sciences
Pharmacology and Therapeutics
Academic Positions
2019 - Present
2019 - PresentProfessor
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2017 - 2019
2017 - 2019Associate Professor
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
2002 - 2017
2002 - 2017Research Assistant
Gazi University, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri
Managerial Experience
2018 - 2021
2018 - 2021Vice Dean
Gazi University, Eczacılık Fakültesi
Non Academic Experience
2016 - 2016
2016 - 2016Konuk Araştırmacı
Dipartimento di Farmacia, Università di Parma, Italia, Konuk Araştırmacı
2007 - 2007
2007 - 2007Konuk Araştırmacı
Dipartimento di Chimica e Tecnologia del Farmaco, Università di Perugia, Italia, Konuk Araştırmacı
Courses
Supervised Theses
2025
2025Doctorate
YENİ NİKOTİNAMİT FOSFORİBOZİLTRANSFERAZ (NAMPT) İNHİBİTÖRÜ/SİRTUİN-1 (SIRT-1) AKTİVATÖRÜ HİBRİT BİLEŞİKLERİN TASARIMI, SENTEZİ VE BİYOLOJİK AKTİVİTELERİNİN BELİRLENMESİ
Eren G. (Consultant)
F.ÖZGENCİL(Student)
2025
2025Doctorate
ARİL 1,3,4-OKSADİAZOL/TİYADİAZOL ASETAMİT YAPISINDA SİRTUİN İNHİBİTÖRÜ OLABİLECEK BİLEŞİKLERİN TASARIMI, SENTEZİ VE BİYOLOJİK AKTİVİTE ÇALIŞMALARI
Eren G. (Consultant)
A.BUĞRA(Student)
2023
2023Doctorate
ARİLOKSİARİL ASETAMİT YAPISINDA SİRTUİN İNHİBİTÖRÜ OLABİLECEK BİLEŞİKLERİN TASARIMI, SENTEZİ VE BİYOLOJİK AKTİVİTE ÇALIŞMALARI
Eren G. (Consultant)
S.GÖZDE(Student)
2021
2021Postgraduate
DESIGN, SYNTHESIS AND BIOLOGICAL ACTIVITY STUDIES ON ARYLOXY BENZAMIDE DERIVATIVES WITH POTENTIAL INHIBITORY EFFECT AGAINST SIRTUIN
Eren G. (Consultant)
S.YAĞCI(Student)
2019
2019Postgraduate
YENİ NİKOTİNAMİT FOSFORİBOZİLTRANSFERAZ (NAMPT) İNHİBİTÖR ADAYLARININ SANAL TARAMA YÖNTEMİ İLE KEŞFİ VE BİYOLOJİK ETKİLERİNİN BELİRLENMESİ
Eren G. (Consultant)
F.ÖZGENCİL(Student)
Articles
All (47)
SCI-E, SSCI, AHCI (45)
SCI-E, SSCI, AHCI, ESCI (45)
Scopus (47)
TRDizin (1)
2025
20251. Targeting SIRT2 with Oxadiazole/Thiadiazole-Based Acetamides: In Silico Screening and In Vitro Cytotoxicity Evaluation
Aksel A. B., GÖZELLE M., BAKAR ATEŞ F., ÖZKAN Y., Ozkan E., EREN G.
POLYCYCLIC AROMATIC COMPOUNDS
, 2025 (SCI-Expanded)
2025
20252. In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits
GÖZELLE M., BAKAR ATEŞ F., Massarotti A., Ozkan E., Gunindi H. B., ÖZKAN Y., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
, vol.43, no.4, pp.1756-1767, 2025 (SCI-Expanded)
2025
20253. 3-Hydroxytyrosol as a phenolic cholinesterase inhibitor with antiamnesic activity: a multimethodological study of selected plant phenolics
Ucar Akyurek T., ŞENOL DENİZ F. S., SÜNTAR İ., EREN G., ULUTAŞ O. K., ERDOĞAN ORHAN .
Frontiers in Pharmacology
, vol.16, 2025 (SCI-Expanded)
2024
20244. Symmetrical 2,7-disubstituted 9H-fluoren-9-one as a novel and promising scaffold for selective targeting of SIRT2
KAYA S. G., EREN G., Massarotti A., GÜNİNDİ H. B., BAKAR ATEŞ F., Ozkan E.
ARCHIV DER PHARMAZIE
, vol.357, no.12, 2024 (SCI-Expanded)
2024
20245. Spectroscopic, electrochemical, and molecular docking studies of the interaction between the antihistamine drug desloratadine and dsDNA
BİLKAY M., Kanbes-Dindar C., BOZAL PALABIYIK B., EREN G., ŞATANA KARA H. E., USLU B.
Analytical Biochemistry
, vol.694, 2024 (SCI-Expanded)
2024
20246. Evaluation of Selected Plant Phenolics via Beta-Secretase-1 Inhibition, Molecular Docking, and Gene Expression Related to Alzheimer's Disease
Uçar Akyürek T., ERDOĞAN ORHAN ., ŞENOL DENİZ F. S., EREN G., Acar B., Sen A.
PHARMACEUTICALS
, vol.17, no.11, 2024 (SCI-Expanded)
2024
20247. Dual-targeted NAMPT inhibitors as a progressive strategy for cancer therapy
Ozgencil F., Günindi H. B., Eren G.
BIOORGANIC CHEMISTRY
, vol.149, 2024 (SCI-Expanded)
2024
20248. 2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition
Kaya S. G., Eren G., Massarotti A., Bakar-Ates F., Ozkan E., Gozelle M., et al.
DRUG DEVELOPMENT RESEARCH
, vol.85, no.4, 2024 (SCI-Expanded)
2024
20249. Linker and tail group modifications on 2-((4-isopropyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-phenoxyphenyl)acetamide to improve SIRT2 inhibitory potency
GÖZELLE M., ÖZKAN Y., EREN G.
FABAD JOURNAL OF PHARMACEUTICAL SCIENCES , vol.49, no.2, pp.317-332, 2024 (Scopus)
2024
202410. Selective inhibition of SIRT2: A disputable therapeutic approach in cancer therapy
KAYA S. G., EREN G.
BIOORGANIC CHEMISTRY
, vol.143, pp.107038-0, 2024 (SCI-Expanded)
2023
202311. Field-based 3D-QSAR studies on amide- and urea-containing NAMPT inhibitors
ÖZGENCİL F., EREN G.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
, vol.242, 2023 (SCI-Expanded)
2023
202312. Evaluation of the interaction between antiviral drug and DNA/BSA via comprehensive multispectral methods and molecular docking studies
Oznur A., EREN G., ŞATANA KARA H. E.
Journal of Photochemistry and Photobiology A: Chemistry
, vol.445, 2023 (SCI-Expanded)
2023
202313. Elucidating the interaction of antidepressant drug paroxetine with ct-dsDNA: A comparative study by electrochemical, spectroscopic, and molecular docking approaches
Nimal R., Unal D. N., Erkmen C., KURBANOĞLU S., Siddiq M., EREN G., et al.
BIOELECTROCHEMISTRY
, vol.149, 2023 (SCI-Expanded)
2023
202314. Absolute configuration of spiro-flavostilbenoids from Yucca schidigera Roezl ex Ortgies: First indication of (2R)-naringenin as the key building block
Pecio Ł., Alilou M., Kozachok S., Orhan I. E., Eren G., Şenol Deniz F. S., et al.
PHYTOCHEMISTRY
, vol.207, no.-, pp.1-7, 2023 (SCI-Expanded)
2022
202215. Development of the electrochemical, spectroscopic and molecular docking approaches toward the investigation of interaction between DNA and anti-leukemic drug azacytidine
Nimal R., Nur Unal D., Erkmen C., BOZAL PALABIYIK B., Siddiq M., EREN G., et al.
Bioelectrochemistry
, vol.146, 2022 (SCI-Expanded)
2022
202216. Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity
Gözelle M., Kaya S. G., Aksel A. B., Özkan E., Bakar Ateş F., Özkan Y., et al.
Bioorganic Chemistry
, vol.123, pp.105746, 2022 (SCI-Expanded)
2022
202217. Evaluation of the Interaction of Cinacalcet with Calf Thymus dsDNA: Use of Electrochemical, Spectrofluorimetric, and Molecular Docking Methods
Erkmen C., Unal D. N., KURBANOĞLU S., EREN G., USLU B.
BIOSENSORS-BASEL
, vol.12, no.5, 2022 (SCI-Expanded)
2022
202218. Flavonoids as Sirtuin Modulators
Deniz F. S., Eren G., Orhan I. E.
CURRENT TOPICS IN MEDICINAL CHEMISTRY
, vol.22, no.9, pp.790-805, 2022 (SCI-Expanded)
2022
202219. Phosphodiesterase-3 Enzyme Inhibitor Drug Milrinone Interaction with DNA and HSA: Electrochemical, Spectroscopic and Molecular Docking
Unal D. N., Erkmen C., Selcuk O., KURBANOĞLU S., EREN G., USLU B.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
, vol.169, no.2, 2022 (SCI-Expanded)
2021
202120. Insecticidal activity of forty-seven marine algae species from the Mediterranean, Aegean, and Sea of Marmara in connection with their cholinesterase and tyrosinase inhibitory activity
Kilic M., ERDOĞAN ORHAN İ., EREN G., OKUDAN E. Ş., Estep A. S., Bencel J. J., et al.
South African Journal of Botany
, vol.143, pp.435-442, 2021 (SCI-Expanded)
2021
202121. Synthesis, in vitro antiprotozoal activity, molecular docking and molecular dynamics studies of some new monocationic guanidinobenzimidazoles
Doganc F., ÇELİK İ., EREN G., Kaiser M., Brun R., Goker H.
European Journal of Medicinal Chemistry
, vol.221, 2021 (SCI-Expanded)
2021
202122. The potential of 4-aryl-6-morpholino-3(2H)-pyridazinone-2-arylpiperazinylacetamide as a new scaffold for SIRT2 inhibition: in silico approach guided by pharmacophore mapping and molecular docking
ŞÜKÜROĞLU M. K., GÖZELLE M., ÖZKAN Y., EREN G.
MEDICINAL CHEMISTRY RESEARCH
, vol.30, no.10, pp.1915-1924, 2021 (SCI-Expanded)
2021
202123. Butyrylcholinesterase-inhibiting natural coumarin molecules as potential leads
Erdoğan Orhan İ., Tosun F., Şenol Deniz F. S., Eren G., Mıhoğlugil F., Akalgan D., et al.
Phytochemistry Letters
, vol.44, pp.48-54, 2021 (SCI-Expanded)
2021
202124. Electrochemical Biosensor Design with Multi-walled Carbon Nanotube to Display DNA-Schiff Base Interaction
Munir A., Bozal-Palabiyik B., EREN G., Shah A., Ali S., Uddin N., et al.
ELECTROANALYSIS
, vol.33, pp.1761-1770, 2021 (SCI-Expanded)
2021
202125. Erodium birandianum Ilarslan & Yurdak. shows anti-gout effect through xanthine oxidase inhibition: Combination of in vitro and in silico techniques and profiling of main components by LC-Q-ToF-MS
Baki Kekilli E., Erdoğan Orhan İ., Şenol Deniz F. S., Eren G., Emerce E., Kahraman A., et al.
Phytochemistry Letters
, vol.43, pp.80-87, 2021 (SCI-Expanded)
2021
202126. Outlining In Vitro and In Silico Cholinesterase Inhibitory Activity of Twenty-Four Natural Products of Various Chemical Classes: Smilagenin, Kokusaginine, and Methyl Rosmarinate as Emboldening Inhibitors
ŞENOL DENİZ F. S., EREN G., ERDOĞAN ORHAN İ., Sener B., ÖZGEN U., Aldaba R., et al.
MOLECULES
, vol.26, no.7, 2021 (SCI-Expanded)
2021
202127. Synthesis and Cytotoxicity of Some Imidazo[4,5-b]pyridine Derivatives and Their Regioselective N-Alkylation
Doganc F., Alp M., Karabay A., Koç A., EREN G., Göker H.
ChemistrySelect
, vol.6, no.7, pp.1519-1525, 2021 (SCI-Expanded)
2021
202128. Molecular approach to promising cholinesterase inhibitory effect of several amaryllidaceae alkaloids: Further re-investigation
Orhan İ., ŞENOL DENİZ F. S., EREN G., Sener B.
South African Journal of Botany
, vol.136, pp.175-181, 2021 (SCI-Expanded)
2021
202129. Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT
Yagci S., Gözelle M., Kaya S. G., Özkan Y., Aksel A. B., Bakar-Ates F., et al.
BIOORGANIC & MEDICINAL CHEMISTRY
, vol.30, 2021 (SCI-Expanded)
2020
202030. Cognitive Facilitation and Antioxidant Effects of an Essential Oil Mix on Scopolamine-Induced Amnesia in Rats: Molecular Modeling of In Vitro and In Vivo Approaches
Boiangiu R. S., Brinza I., Hancianu M., Erdoğan Orhan İ., Eren G., Gunduz E., et al.
MOLECULES
, vol.25, no.7, 2020 (SCI-Expanded)
2020
202031. Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening
Ozgencil F., EREN G., ÖZKAN Y., GÜNTEKİN ERGÜN S., ATALAY R.
BIOORGANIC & MEDICINAL CHEMISTRY
, vol.28, no.1, 2020 (SCI-Expanded)
2019
201932. Yuccalechins A-C from the Yucca schidigera Roezl ex Ortgies Bark: Elucidation of the Relative and Absolute Configurations of Three New Spirobiflavonoids and Their Cholinesterase Inhibitory Activities
Pecio L., Alilou M., Kozachok S., ERDOĞAN ORHAN İ., EREN G., ŞENOL DENİZ F. S., et al.
MOLECULES
, vol.24, no.22, 2019 (SCI-Expanded)
2019
201933. Novel pyridazinone derivatives as butyrylcholinesterase inhibitors
Dündar Y., Kuyrukçu Öztürk Ö., Eren G., Şenol Deniz F. S., Önkol T., Erdoğan Orhan İ.
BIOORGANIC CHEMISTRY
, vol.92, 2019 (SCI-Expanded)
2019
201934. Pharmacophore modeling and virtual screening studies to identify novel selective SIRT2 inhibitors
Eren G., Bruno A., Guntekin-Ergun S., Atalay R., Ozgencil F., Özkan Y., et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
, vol.89, pp.60-73, 2019 (SCI-Expanded)
2019
201935. A novel Trans-Pt(II) complex bearing 2-acetoxymethylbenzimidazole as a non-leaving ligand (trans-[Pt(AMBi)(2)Cl-2]): Synthesis, antiproliferative activity, DNA interaction and molecular docking studies compared with its cis isomer (cis-[Pt(AMBi)(2)Cl-2])
EREN G., EMERCE E., AÇIK L., AYDIN B., Gumus F.
JOURNAL OF MOLECULAR STRUCTURE
, vol.1184, pp.512-518, 2019 (SCI-Expanded)
2018
201836. In Vitro Cytotoxic Activities of Platinum(II) Complex with 1-Methyl-2-(3 '-hydroxypropyl)benzimidazole and 2-(3 '-Hydroxypropyl)benzimidazolium Hexa- and Tetrachloroplatinate Salts
EREN G., Yilmaz S., Gumus F.
LETTERS IN DRUG DESIGN & DISCOVERY
, vol.15, no.1, pp.65-69, 2018 (SCI-Expanded)
2017
201737. Homology Modeling of Human Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 2: Insights into Isoenzyme-Specific Differences Using Molecular Docking Simulatons
EREN G.
LETTERS IN DRUG DESIGN & DISCOVERY
, vol.14, no.6, pp.727-736, 2017 (SCI-Expanded)
2012
201238. In vitro Cytotoxic Activities of Platinum II Complexes Containing 2 Acetoxymethyl and 2 2 Hydroxyethyl benzimidazole Ligands
EREN G., GÜMÜŞ F., Yılmaz Ş.
The FABAD Journal of Pharmaceutical Sciences , vol.36, no.2, pp.69-73, 2012 (Scopus)
2012
201239. Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP)
BANOĞLU E., ÇALIŞKAN B., Luderer S., EREN G., Ozkan Y., Altenhofen W., et al.
BIOORGANIC & MEDICINAL CHEMISTRY
, vol.20, no.12, pp.3728-3741, 2012 (SCI-Expanded)
2012
201240. From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors
EREN G., Macchiarulo A., BANOĞLU E.
MOLECULAR INFORMATICS
, vol.31, no.2, pp.123-134, 2012 (SCI-Expanded)
2010
201041. Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors
EREN G., Unlu S., Nunez M., Labeaga L., Ledo F., Entrena A., et al.
BIOORGANIC & MEDICINAL CHEMISTRY
, vol.18, no.17, pp.6367-6376, 2010 (SCI-Expanded)
2009
200942. Charting the Chemical Space of Target Sites: Insights into the Binding Modes of Amine and Amidine Groups
Macchiarulo A., Nuti R., EREN G., Pellicciari R.
JOURNAL OF CHEMICAL INFORMATION AND MODELING
, vol.49, no.4, pp.900-912, 2009 (SCI-Expanded)
2009
200943. Synthesis, Cytotoxicity, and DNA Interactions of New Cisplatin Analogues Containing Substituted Benzimidazole Ligands
Gumus F., EREN G., AÇIK L., ÇELEBİ KESKİN A., Ozturk F., Yilmaz S., et al.
JOURNAL OF MEDICINAL CHEMISTRY
, vol.52, no.5, pp.1345-1357, 2009 (SCI-Expanded)
2008
200844. On the way to selective PARP-2 inhibitors. Design, synthesis, and prelimionary evaluation of a series of isoquinolinone derivatives
Pellicciari R., Camaioni E., Costantino G., Formentini L., Sabbatini P., Venturoni F., et al.
CHEMMEDCHEM
, vol.3, no.6, pp.914-923, 2008 (SCI-Expanded)
2007
200745. Synthesis, characterization and preliminary screening of regioisomeric 1-(3-pyridazinyl)-3-arylpyrazole and 1-(3-pyridazinyl)-5-arylpyrazole derivatives towards cyclooxygenase inhibition
Unlu S., BANOĞLU E., Ito S., Niiya T., EREN G., Okcelik B., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, vol.22, no.3, pp.351-361, 2007 (SCI-Expanded)
2005
200546. The crystal structures of 2-(3 '-hydroxypropyl)benzimidazolium hexa- and tetrachloroplatinate
Elmali A., Elerman Y., EREN G., Gumus F., Svoboda I.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
, vol.60, no.2, pp.164-168, 2005 (SCI-Expanded)
2003
200347. Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum(II) complexes with 2-substituted benzimidazole ligands
Gumus F., Algul O., EREN G., Eorglu H., Diril N., Gur S., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, vol.38, no.5, pp.473-480, 2003 (SCI-Expanded)
Papers Presented at Peer-Reviewed Scientific Conferences
2024
20241. Pistacia atlantica Desf’in İn vitro ve İn siliko Yöntemlerle Metabolizma Hastalıkları Üzerindeki Etki Potansiyelinin İncelenmesi
Pekacar S., Deliorman Orhan D., Şöhretoğlu D., Šoral M., Özgencil F., Eren G.
25. Bitkisel İlaç Hammaddeleri Toplantısı (BİHAT 2024), Lefkoşa, Cyprus (Kktc), 7 - 10 November 2024, (Summary Text)
2024
20242. Ariloksiaril Asetamit Yapısında Sirtuin İnhibitörü Olabilecek Bileşiklerin Tasarımı, Sentezi ve Biyolojik Aktivite Çalışmaları
KAYA S. G., ÖZKAN Y., BAKAR ATEŞ F., ÖZKAN E., EREN G.
VII. Ulusal Farmasötik Kimya Kongresi, İzmir, Turkey, 26 - 28 October 2024, (Summary Text)
2024
20243. Virtual Screening using Structure-based Pharmacophore to Identify Novel NAPRT Inhibitors
GÜNİNDİ H. B., MASSAROTTI A., EREN G.
24th European Symposium on Quantitative Structure-Activity Relationship, Barselona, Spain, 22 - 26 September 2024, (Summary Text)
2024
20244. DEVELOPING A FIELD-BASED 3D-QSAR MODEL THROUGH SIRT2INHIBITORY PROFILES OF IN-HOUSE COMPOUNDS
Özgencil F., Eren G.
24th European Symposium on Quantitative Structure-Activity Relationship 24th European ip, Barcelona, Spain, 22 - 26 September 2024, (Summary Text)
2024
20245. Phytochemical and Activity Studies on Geranium Subcaulescens
Özüpek B., Şöhretoğlu D., Sˇoral M., Özgencil F., Eren G., Deliorman Orhan D.
International Congress on Integrative Medicine and Health, Ohio, United States Of America, 11 - 13 April 2024, pp.54-55, (Summary Text)
2023
20236. Screening of Some Plant-Derived Compounds Against Enzymes Associated With Alzheimer's Disease By In Vitro and In Silico Method
Şenol Deniz F. S., Eren G., Erdoğan Orhan İ.
9th International Mediterranean Symposium on Medicinal and Aromatic Plants (MESMAP-9), Ankara, Turkey, 3 - 05 May 2023, pp.1, (Summary Text)
2022
20227. 3D-QSAR Studies on Amide and Urea Derivatives as NAMPT Inhibitors
ÖZGENCİL F., EREN G.
9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022, (Summary Text)
2022
20228. In Silico Hit Optimization toward SIRT2 Inhibition: N-aryloxyaryl-2-(arylthio)acetamides
KAYA S. G., ÖZKAN Y., EREN G.
9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022, (Summary Text)
2022
20229. N-(5-(3-Methoxybenzyl)/(pyrimidin-2-yl-methyl))-1,3,4-oxadiazol-2-yl)-2-(arylthio)acetamide Derivatives as SIRT2 Inhibitors
AKSEL A. B., ÖZKAN Y., EREN G.
9th EFMC Young Medicinal Chemists' Symposium (EFMC-YMCS 2022), Nice, France, 8 - 09 September 2022, (Summary Text)
2022
202210. Spektroskopik ve Elektrokimyasal Tekniklerle Antikanser İlaç Azasitidin-DNA Arasindaki Etkileşimin İncelenmesi
Ünal D. N., Nimal R., ERKMEN C., BOZAL PALABIYIK B., Siddiq M., EREN G., et al.
10. Ulusal Analitik Kimya Kongresi, Muğla, Turkey, 7 - 11 September 2022, (Summary Text)
2022
202211. Yeni Nikotinamit Fosforiboziltransferaz (NAMPT) İnhibitör Adaylarının Sanal Tarama Yöntemi ile Keşfi ve Biyolojik Etkilerinin Belirlenmesi
ÖZGENCİL F., ÖZKAN Y., EREN G.
VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Turkey, 26 - 29 August 2022, (Summary Text)
2022
202212. Ariloksi Benzamit Yapısında Sirtuin İnhibitörü Olabilecek Bileşiklerin Tasarımı, Sentezi ve Biyolojik Aktivite Çalışmaları
YAĞCI S., GÖZELLE M., ÖZKAN Y., BAKAR ATEŞ F., EREN G.
VI. Ulusal Farmasötik Kimya Kongresi, İstanbul, Turkey, 26 - 29 August 2022, (Summary Text)
2023
202313. Electrochemical, Spectrofluorimetric & Molecular Docking Approaches to Evaluate the Interaction of Cinacalcet HCl with Calf-Thymus dsDNA
Ünal D. N., ERKMEN C., KURBANOĞLU S., EREN G., USLU B.
33rd International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2023), Ankara, Turkey, 2 - 06 July 2023, (Summary Text)
2021
202114. SIRT2 Inhibitory Activities of N-Aryloxyphenyl-2-(arylthio)acetamide Derivatives
KAYA S. G., ÖZKAN Y., EREN G.
GPSS-2021, 3rd International Gazi Pharma Symposium Series, Turkey, 8 - 10 September 2021, (Summary Text)
2021
202115. N-(5-Arylmethyl-1,3,4-oxadiazole-2-yl)-2-(arylthio)acetamide as a New Scaffold for Developing Small-molecule SIRT Inhibitors
AKSEL A. B., ÖZKAN Y., EREN G.
GPSS-2021, 3rd International Gazi Pharma Symposium Series, Turkey, 8 - 10 September 2021, (Summary Text)
2021
202116. Discovery of 5-Benzyl-1,3,4-oxadiazole/thiadiazole-2-carboxamides as Potential Leads for Selective SIRT2 Inhibition
GÖZELLE M., ÖZKAN Y., EREN G.
GPSS-2021, 3rd International Gazi Pharma Symposium Series, Ankara, Turkey, 8 - 10 September 2021, (Summary Text)
2021
202117. Investigation of Interaction Between Milrinone and DNA by Electrochemical, Spectroscopic and Molecular Docking Study
USLU B., ÜNAL D. N., ERKMEN C., SELÇUK Ö., EREN G., KURBANOĞLU S.
PBA2021, International Symposium on Pharmaceutical and Biomedical Analysis, Kyoto, Japan, 29 August - 01 September 2021, (Summary Text)
2019
201918. Novel Pyridazinone Derivatives as Selective Butrylcholinesterase Inhibitors
DÜNDAR Y., KUYRUKÇU Ö., EREN G., ŞENOL DENİZ F. S., ERDOĞAN ORHAN İ.
EFMC- YMCS, 6th EFMC Young Medicinal Chemist Symposium, 5 - 06 September 2019, (Summary Text)
2019
201919. Design and Synthesis of Aryloxy Benzamide Derivatives with Potential Inhibitory Effect against SIRT2
YAGCI S., GÖZELLE M., KAYA S. G., EREN G.
EFMC-YMCS, 6th EFMC Young Medicinal Chemist Symposium, 5 - 06 September 2019, (Summary Text)
2018
201820. Yapısında taşıyıcı ligand olarak 2-asetoksimetilbenzimidazol bulunduran cis ve trans-Pt(II) komplekslerinin karşılaştırmalı in vitro sitotoksik etkileri
Eren G., Emerce E., Gümüş F.
UMEK-2, 2. Ulusal Marmara Eczacılık Kongresi, Turkey, 14 - 16 November 2018, (Summary Text)
2018
201821. Karbamat Yapısı Taşıyan Piridazin Türevlerinin Sentezi, Asetilkolinesteraz/ Butirilkolinesteraz İnhibitör Aktiviteleri ve Moleküler Modelleme Çalışmaları
KUYRUKÇU Ö., ŞENOL DENİZ F. S., EREN G., ERDOĞAN ORHAN İ., DÜNDAR Y.
2. Ulusal Marmara Eczacılık Kongresi (UMEK-2), Turkey, 14 - 16 November 2018, (Summary Text)
2017
201722. In Vitro Cytotoxic Activities of Platinum(II) Complex with 1-Methyl-2-(3’xx-hydroxypropyl)benzimidazole and 2-(3’xx-Hydroxypropyl)benzimidazole Hexa- and Tetrachloroplatinate Salts
EREN G., YILMAZ Ş., GÜMÜŞ F.
2nd International Gazi Pharma Symposium Series (GPSS2017), 11 - 13 October 2017, (Summary Text)
2007
200723. Towards Selective PARP-2 Inhibitors: Design, Synthesis and Preliminary Evaluation of a Series of Isoquinoline Derivatives
CAMAIONI E., SABBATINI P., COSTANTINO G., FORMENTINI L., VENTURONI F., BELLOCCHI D., et al.
Frontiers in CNS and Oncology Medicinal Chemistry, ACS-EFMC, Siena, Italy, 7 - 09 October 2007, (Summary Text)
2016
201624. Pharmacophore Based Virtual Screening to Identify Novel SIRT2 Inhibitors
EREN G., BRUNO A., COSTANTINO G.
21st EuroQSAR, Where Molecular Simulations Meet Drug Discovery, 4 - 08 October 2016, (Summary Text)
2016
201625. Homology Modeling of Human Nicotinamide Mononucleotide Adenylyltransferase 2 Insights into Isoenzyme Specific Differences Using Molecular Docking Simulations
GOZELLE M., EREN G.
21st EuroQSAR, Where Molecular Simulations Meet Drug Discovery, 4 - 08 October 2016, (Summary Text)
2014
201426. Towards Pharmacophore and Docking based Virtual Screening of Human P2Y12 Receptor Antagonists with the Homology modeled Protein Structure
EREN G., BANOĞLU E.
20th EuroQSAR, Understanding Chemical-Biological Interactions, St. Petersburg, Russia, 31 August - 04 September 2014, (Summary Text)
2012
201227. From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors
EREN G., MACCHIARULO A., BANOĞLU E.
EFMC-ISMC 2012, XXIInd International Symposium on Medicinal Chemistry, Berlin, Germany, 2 - 06 September 2012, (Summary Text)
2012
201228. New 4,5-Diarylisoxazole Derivatives as Novel Inhibitors of Human 5-Lipoxygenase (5-LO)
ÇALIŞKAN B., LUDERER S., GERSTMEIER J., EREN G., WERZ O., BANOĞLU E.
EFMC-ISMC 2012, XXIInd International Symposium on Medicinal Chemistry, Berlin, Germany, 2 - 06 September 2012, (Summary Text)
2011
201129. New Isoxazole Derivatives as Novel Inhibitors of 5-Lipoxygenase
ÇALIŞKAN B., LUDERER S., EREN G., WERZ O., BANOĞLU E.
4th International Symposium on Advanced in Synthetic and Medicinal Chemistry, St. Petersburg, Russia, 21 - 25 August 2011, (Summary Text)
2011
201130. From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors
EREN G., MACCHIARULO A., BANOĞLU E.
VIII EWDD, Eighth European Workshop in Drug Design, Siena, Italy, 22 - 28 May 2011, (Summary Text)
2010
201031. An Approach to Combined Ligand- and Structure-Based Virtual Screening and QSAR Studies for Determining Novel 5-Lipoxygenase Inhibitors
EREN G., BANOĞLU E.
IMMPC-ISPC Joint Meeting, 4th International Meeting on Medicinal and Pharmaceutical Chemistry, 6th International Symposium on Pharmaceutical Chemistry, Ankara, Turkey, 30 September - 02 October 2010, (Summary Text)
2010
201032. Studies on Synthesis and In Vitro Cyclooxygenase Inhibitory Activities of Diaryl Heterocyclic Compounds
EREN G., ÜNLÜ S., NUNEZ M. T., LABEAGA L., ENTRENA A., BANOĞLU E., et al.
EFMC-ISMC 2010, XXIst International Symposium on Medicinal Chemistry, Brüksel, Belgium, 5 - 09 September 2010, (Summary Text)
2009
200933. Diaril Heterosiklik Yapıda Siklooksijenaz İnhibitörü Olabilecek Bileşiklerin Sentezi ve İn Vitro İnhibitör Etki Tayinleri Üzerinde Çalışmalar
Eren G.
II. Ulusal Farmasötik Kimya Kongresi, Mersin, Turkey, 13 - 15 November 2009, pp.1-2, (Summary Text)
2009
200934. Combining of Ligand- and Structure-Based Information to Derive a Pharmacophore Model for Determining Novel FLAP Inhibitors
EREN G., ALTENHOFEN W., BANOĞLU E.
Vienna Summer School on Drug Design, Viyena, Austria, 13 - 18 September 2009, (Summary Text)
2009
200935. Synthesis and Cytotoxicity of New Cisplatin Analogues Containing Substituted Benzimidazole Ligands
EREN G., GÜMÜŞ F., GÜR S., ÖZKUL A.
3rd International Symposium on Advances in Synthetic and Medicinal Chemistry, Kiev, Ukraine, 23 - 27 August 2009, (Summary Text)
2007
200736. Homology Modeling of Human 5-Lipoxygenase and Molecular Docking Simulations of Competitive Inhibitors
EREN G., ÇALIŞKAN B., COSTANTINO G., MACCHIARULO A., ÜNLÜ S., ÇAKIR B., et al.
3rd International Meeting on Medicinal and Pharmaceutical Chemistry, IMMPC-3, Antalya, Turkey, 16 - 21 October 2007, (Summary Text)
2006
200637. Bazı Benzimidazol Türevlerinin Platin II Komplekslerinin Sentezi ve İn Vitro Antitümör Aktiviteleri Üzerinde Çalışmalar
EREN G., GÜMÜŞ F.
I. Ulusal Farmasötik Kimya Kongresi, İstanbul, Turkey, 11 - 13 November 2006, (Summary Text)
2006
200638. Studies on synthesis and in vitro COX inhibitory activities of diaryl heterocyclic compounds
EREN G.
European Network of Doctoral Studies in Pharmaceutical Sciences, 3rd Annual Meeting, Catania, Italy, 03 November 2006, (Summary Text)
2006
200639. Synthesis, Characterizaton and Preliminary Screening of Regioisomeric 1-(3-Pyridazinyl)-3-arylpyrazole and 1-(3-Pyridazinyl)-5-arylpyrazole Derivatives Towards Cyclooxygenase Inhibition
ÜNLÜ S., BANOĞLU E., SHIGERU I., NIIYA T., EREN G., ÖKÇELİK B., et al.
XIXth International Symposium on Medicinal Chemistry, ISMC 2006, İstanbul, Turkey, 29 August - 02 September 2006, (Summary Text)
Books
2021
20211. Kantitatif Yapı Etki İlişkileri [QSAR]
Eren G.
in: Medisinal Kimya, Alp Mehmet, Editor, Akademisyen Yayınevi, Ankara, pp.846-864, 2021
2018
20182. Türk Farmakopesi
TUNÇBİLEK M., YEŞİLADA A., BALKAN A., TOZKOPARAN B., PALASKA E., ÖZKANLI F., et al.
T. C. Sağlık Bakanlığı Türkiye İlaç ve Tıbbi Cihaz Kurumu, Ankara, 2018
Funded Projects
2025 - Present
2025 - PresentSanal Tarama Çıktısı Bileşiklerin NAPRT Enzimi Üzerine Etkilerinin Değerlendirilmesi
Project Supported by Higher Education Institutions , BAP Research Project
EREN G. (Executive), ÇİMEN H., GÜNİNDİ H. B.
2024 - Present
2024 - PresentNAMPT İnhibitorü ve SIRT1 Aktivatörü Olarak İkili Etki Gösteren Moleküllerin Geliştirilmesi
Project Supported by Higher Education Institutions , BAP Research Project
EREN G. (Executive), ÖZGENCİL F., ÇİMEN H., MASSAROTTİ A., ÇİMEN H., ÇİMEN H.
2024 - 2025
2024 - 2025NAMPT İnhibisyonunu ve SIRT1 Aktivasyonunu Hedef Alan Dual Etkili Moleküllerin Geliştirilmesi
TUBITAK Project , 1002 - Quick Support Program
Özgencil F. (Executive), Eren G.
2023 - 2025
2023 - 2025SIRT2 İnhibisyon Potansiyelini Geliştirmek Amacıyla Lider Molekül Üzerinde Gerçekleştirilen Yapısal Modifikasyonlar
TUBITAK Project , 1002 - Quick Support Program
Eren G. (Executive), Aksel A. B., Özkan Y.
2022 - 2025
2022 - 2025Öncü Bileşik Optimizasyonu İle Tasarlanan Antikanser Etkili Olabilecek Yeni Bileşiklerin Sentezi, Yapı-Etki İlişkileri Ve Moleküler Etki Mekanizmalarının İncelenmesi
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Baytaş S. (Executive), EREN G.
2024 - 2024
2024 - 2024NAMPT İnhibitörü ve SIRT1 Aktivatörü Olarak Dual Etki Gösterebilecek Bileşiklerin In Vitro NAMPT İnhibitör Etkilerinin Belirlenmesi
TUBITAK Project , 1002 - Quick Support Program
(Project Abstract)
Özgencil F. (Executive), Eren G.
2022 - 2024
2022 - 2024Çok Hedefli İlaç Yaklaşımı: NAMPT İnhibitörü ve SIRT1 AktivatörüOlarak Dual Etki Gösteren Moleküllerin Sanal Tarama Yöntemi ile Keşfi
Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
Eren G., Özgencil F. (Executive)
2022 - 2024
2022 - 2024Yeni 2,7-Disübstitüe 9H-Fluoren-9-on Türevleri: Tasarımı, Sentezi ve SIRT2 İnhibitör Etkilerinin Araştırılması
Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
Kaya S. G., Eren G. (Executive), Özkan Y.
2021 - 2024
2021 - 2024Öncü Bileşik Optimizasyonu ile Yeni Selektif SIRT2 İnhibitörlerinin Geliştirilmesi
Project Supported by Higher Education Institutions , BAP Research Project
EREN G. (Executive), ÖZGENCİL F., AKSEL A. B., ÖZKAN Y., GÖZELLE M., BAKAR ATEŞ F., et al.
2020 - 2023
2020 - 2023Kanserde İmmunoterapi Etkinliğinin İyileştirilmesine Yönelik Makine Öğrenmesine Dayalı Yeni Gen Keşfi ve İlaç Yeniden Konumlandırma Platformunun Geliştirilmesi
TUBITAK Project , 1003 - Priority Areas R&D Projects Support Program
Eren G.
2018 - 2022
2018 - 2022Yeni Selektif SIRT2 İnhibitörlerinin Tasarımı, Sentezi, Biyolojik Aktivitelerinin Tayini ve Yapı-Etki İlişkilerinin İncelenmesi
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Eren G. (Executive), Gözelle M., Özkan Y., Bakar Ateş F.
2018 - 2019
2018 - 2019Yeni NAMPT İnhibitörlerinin Sanal Tarama Yöntemi ile Keşfi
TUBITAK Project , 1002 - Quick Support Program
Eren G. (Executive)
2017 - 2019
2017 - 2019Bazi Piridazin Türevlerinin Sentezi Ve Asetilkolinesteraz / Butirilkolinesteraz İnhibitör Aktiviteleri Üzerine Çalişmalar
TUBITAK Project , 3001 - Initial R&D Projects Support Program
Dündar Y. (Executive), Eren G., Erdoğan Orhan İ., Önkol T.
2015 - 2017
2015 - 2017Ligand ve Yapı Temelli Yaklaşımların Birlikte Kullanıldığı Sanal Tarama Yöntemi Ile Yeni SIRT2 İnhibitörlerinin Keşfi
TUBITAK Project , 3001 - Initial R&D Projects Support Program
Eren G. (Executive), Atalay R.
2012 - 2015
2012 - 2015Sübstitüe Benzimidazol Ligandı Taşıyan Yeni Trans-Platin(II) Komplekslerinin Sentezi ve Karakterizasyonu
Project Supported by Higher Education Institutions , BAP Other
EREN G. (Executive)
2012 - 2015
2012 - 2015Sübstitüe Benzimidazol Ligandı Taşıyan Yeni Trans Platin II Komplekslerinin Sentezi ve Karakterizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
Eren G. (Executive), Gümüş F.
2011 - 2014
2011 - 20145-Lipoksijenaz (5-LO) İnhibitörü Olabilecek Yeni Bileşiklerin Sentezi ve Moleküler Modelleme Çalışmaları
Project Supported by Higher Education Institutions , BAP Other
EREN G. (Executive)
2011 - 2014
2011 - 20145 Lipoksijenaz 5 LO İnhibitörü Olabilecek Yeni Bileşiklerin Sentezi ve Moleküler Modelleme Çalışmaları
Project Supported by Higher Education Institutions , BAP Research Project
EREN G. (Executive)
2011 - 2014
2011 - 2014İzoksazol türevi bileşiklerin sentezi ve 5 lipoksijenaz inhibitör aktivitelerinin değerlendirilmesi
Project Supported by Higher Education Institutions , BAP Research Project
Eren G., Banoğlu E. (Executive), Çalışkan B.
2010 - 2012
2010 - 20125-Lipoksijenaz İnhibitör Etkili Yeni Moleküllerin Moleküler Modelleme Çalışmaları ile Tasarımı
Project Supported by Higher Education Institutions , BAP Other
EREN G. (Executive)
2009 - 2010
2009 - 20105-Lipoksijenaz Aktive Edici Protein (FLAP) İnhibitörü Olabilecek Yeni Bileşiklerin Moleküler Modelleme Yöntemleriyle Tasarımı
Project Supported by Higher Education Institutions , BAP Other
EREN G. (Executive)
Patent
2016
2016LÖKOTRİEN BİYOSENTEZ İNHİBİTÖRLERİ OLARAK İZOKSAZOL TÜREVLERİ
Patent
Registered / Approved, The Invention Registration Number: 2014 05943 , Standard Registration
Memberships and Roles in Scientific Organizations
2019 - Present
2019 - Present
Organisation for Women in Science for the Developing World (OWSD) Turkey National Chapter
Board Member
2017 - 2021
2017 - 2021Türk Farmasötik ve Medisinal Kimya Derneği
Board Member
Awards
April 2011
April 2011