Prof. DENİZ SONGÜL DOĞRUER

Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes

Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer's disease

Erdogan M., Kılıç B. , Sagkan R. I. , Aksakal F., Ercetin T., Gulcan H. O. , et al.

European Journal of Medicinal Chemistry, vol.212, 2021 (Journal Indexed in SCI Expanded)

Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors

Kılıç B. , Erdogan M., Gulcan H. O. , Aksakarl F., Oruklu N. , Bağrıaçık E. Ü. , et al.

MEDICINAL CHEMISTRY, vol.15, no.1, pp.59-76, 2019 (Journal Indexed in SCI)

Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase

Kılıç B. , Gulcan H. O. , Aksakal F., Ercetin T., Oruklu N. , Bagriacik E. U. , et al.

BIOORGANIC CHEMISTRY, vol.79, pp.235-249, 2018 (Journal Indexed in SCI)

Synthesis of Some New 1(2H)-Phthalazinone Derivatives and Evaluation of Their Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities

KILIÇ B. , Gulcan H. O. , Yalcin M., Aksakal F., Dimoglo A., Sahin M. F. , et al.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.14, no.2, pp.159-166, 2017 (Journal Indexed in SCI)

Synthesis of some 3(2H)-pyridazinone and 1(2H)-phthalazinone derivatives incorporating aminothiazole moiety and investigation of their antioxidant, acetylcholinesterase, and butyrylcholinesterase inhibitory activities

Yamali C., Gulcan H. O. , Kahya B. , Cobanoglu S., ŞÜKÜROĞLU M. K. , DOĞRUER D. S.

MEDICINAL CHEMISTRY RESEARCH, vol.24, no.3, pp.1210-1217, 2015 (Journal Indexed in SCI)

Studies on the synthesis of 3-methyl-6-(substituted-urea/-thiourea)-2(3H)-benzothiazolone derivatives and antimicrobial activities

Unal A. S. , KAYNAK ONURDAĞ F., Ozgen S., DOĞRUER D. S. , ÖNKOL T.

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, vol.54, no.2, pp.253-259, 2015 (Journal Indexed in SCI)

Synthesis of Some New 3(2H)-Pyridazinone Derivatives and Evaluation of their Analgesic-anti-inflammatory and Antimicrobial Activities

Sukuroglu M. K. , Yamali C., Tiryaki D., Onurdag F. K. , AKKOL E. , DOĞRUER D. S.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.10, no.6, pp.507-514, 2013 (Journal Indexed in SCI)

Synthesis of some new 2,6-disubstituted-3(2H)-pyridazinone derivatives and investigation of their analgesic, anti-inflammatory and antimicrobial activities

Tiryaki D., Sukuroglu M. K. , DOĞRUER D. S. , AKKOL E. , Ozgen S., Sahin M. F.

MEDICINAL CHEMISTRY RESEARCH, vol.22, no.6, pp.2553-2560, 2013 (Journal Indexed in SCI)

1-[4-(4-Chlorophenyl)piperazin-1-yl]-3-(6-oxo-3,4-diphenyl-1, 6-dihydropyridazin-1-yl)propan-1-one

Aydn A., AKKURT M., DOĞRUER D. S. , Büyükgüngör O.

Acta Crystallographica Section E: Structure Reports Online, vol.68, no.9, 2012 (Journal Indexed in SCI Expanded)

Synthesis of some new urea and thiourea derivatives and evaluation of their antimicrobial activities

Gulkok Y., Bicer T., Onurdag F. K. , Ozgen S., Sahin M. F. , DOĞRUER D. S.

TURKISH JOURNAL OF CHEMISTRY, vol.36, no.2, pp.279-291, 2012 (Journal Indexed in SCI)

Synthesis of some pyridazine derivatives carrying urea, thiourea, and sulfonamide moieties and their antimicrobial activity

Doğruer D. S. , Urlu S., Önkol T. , Özçelik B. , Sahin M. F.

TURKISH JOURNAL OF CHEMISTRY, vol.34, no.1, pp.57-65, 2010 (Journal Indexed in SCI)

2-[2-(4-benzylpiperazin-1-ylcarbonyl)-ethyl]-5,6-diphenylpyridazin-3(2H)-one

AYDIN A., DOĞRUER D. S. , AKKURT M., BÜYÜKGÜNGÖR O.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.64, 2008 (Journal Indexed in SCI)

Synthesis and antimicrobial activity of new 1,2,4-triazole and 1,3,4-thiadiazole derivatives

ÖNKOL T. , DOĞRUER D. S. , Uzun L., Adak S., Oezkan S., Sahin M. F.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, vol.23, no.2, pp.277-284, 2008 (Journal Indexed in SCI)

Synthesis and antimicrobial activity of some 3(2H)-pyridazinone and 1(2H)-phthalazinone derivatives

DOĞRUER D. S. , ÖNKOL T. , Oezkan S., Oezgen S., Sahin M. F.

TURKISH JOURNAL OF CHEMISTRY, vol.32, no.4, pp.469-479, 2008 (Journal Indexed in SCI)

2-(6-Oxo-3,4-diphenyl-1,6-dihydropyridazin-1-yl)acetic acid

Aydin A., DOĞRUER D. S. , Akkurt M., Bueyuekguengoer O.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, vol.63, 2007 (Journal Indexed in SCI)

Synthesis of 2-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]acetamide and 3-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]propanamide derivatives as analgesic and anti-inflammatory agents

DOĞRUER D. S. , ÜNLÜ S. , Küpeli E., Banogǧlu E., ŞAHİN M. G.

Turkish Journal of Pharmaceutical Sciences, vol.4, no.2, pp.57-70, 2007 (Journal Indexed in SCI Expanded)

Synthesis of new 2-[1(2H)-phthalazinon-2-yl]-acetamide and 3-[1(2H)-phthalazinon-2-yl]-propanamide derivatives as antinociceptive and anti-inflammatory agents

DOĞRUER D. S. , Kupeli E., Yesilada E., Sahin M.

ARCHIV DER PHARMAZIE, vol.337, no.6, pp.303-310, 2004 (Journal Indexed in SCI)

3-(4-Aminobutyn-1-y1)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors

DOĞRUER D. S. , Lee M., Dukat M., Damaj I., Martin B., Glennon R.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol.14, no.2, pp.523-526, 2004 (Journal Indexed in SCI)

Synthesis and analgesic and anti-inflammatory activity of new pyridazinones

DOĞRUER D. S. , Sahin M., Kupeli E., Yesilada E.

TURKISH JOURNAL OF CHEMISTRY, vol.27, no.6, pp.727-738, 2003 (Journal Indexed in SCI)

Synthesis and antinociceptive activity of 6-substituted-3-pyridazinone derivatives

Gokce M., DOĞRUER D. S. , Sahin M.

FARMACO, vol.56, no.3, pp.233-237, 2001 (Journal Indexed in SCI)

Synthesis and antinociceptive activity of (5-chloro-2-benzothiazolinon-3-yl)acetamide derivatives

Onkol T., DOĞRUER D. S. , Ito S., Sahin M.

ARCHIV DER PHARMAZIE, vol.333, no.10, pp.337-340, 2000 (Journal Indexed in SCI)

Crystal structure of 1-[2-[6-(4-methoxyphenyl)-3(2H)-pyridazinone-2-yl]acetyl]-4-(2-pyridyl)piperazine

Ingec Ş. , Soylu H., Kendi E., DOĞRUER D. S. , Sahin M.

ANALYTICAL SCIENCES, vol.16, no.6, pp.669-670, 2000 (Journal Indexed in SCI)

Studies on some 3(2H)-pyridazinone derivatives with antinociceptive activity

DOĞRUER D. S. , Sahin M., Unlu S., Ito S.

ARCHIV DER PHARMAZIE, vol.333, no.4, pp.79-86, 2000 (Journal Indexed in SCI)

Synthesis and antinociceptive activity of some 3-substituted benzothiazolone derivatives

Cakir B., Ulucay A., DOĞRUER D. S. , Isimer A., Sahin M.

FARMACO, vol.54, pp.846-851, 1999 (Journal Indexed in SCI)

Synthesis and antinociceptive activity of (1-benzyl-2(3H)-benzimidazolon-3-yl) acetic acid derivatives

Nacak S. , DOĞRUER D. S. , Sahin M.

FARMACO, vol.54, pp.768-772, 1999 (Journal Indexed in SCI)

The in vitro effects of new non-steroidal antiinflammatory compounds on antioxidant system of human erythrocytes

Orhan H., DOĞRUER D. S. , Cakir B., Sahin G., Sahin M.

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, vol.51, pp.397-402, 1999 (Journal Indexed in SCI)

The in vitro hepatic metabolism of 1-phenyl-2-(2-benzothiazolinone-3-yl)ethanone and their reduced derivatives

Yilmaz F., Ulgen M., DOĞRUER D. S. , Cakir B., Sahin M.

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, vol.51, pp.442-445, 1999 (Journal Indexed in SCI)

Anti-nociceptive and anti-inflammatory activity of some (2-benzoxazolone-3-yl and 2-benzothiazolone-3-yl)acetic acid derivatives

Dogruer D. S. , Unlu S., Sahin M., Yesilada E.

Farmaco, vol.53, no.1, pp.80-84, 1999 (Journal Indexed in SCI Expanded)

N-(2-Pyridinyl)-2-[2(3H)-benzazolone-3-YL]acetamides: Synthesis, antinociceptive and anti-inflammatory activity

DOĞRUER D. S. , Unlu S., Yesilada E., Sahin M.

FARMACO, vol.52, no.12, pp.745-750, 1997 (Journal Indexed in SCI)

Articles Published in Other Journals

6-Substituted-2-benzothiazolinone derivatives, synthesis and analgesic activity

ÖNKOL T. , Dogruer S. , ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, vol.16, no.1, pp.25-31, 1999 (Refereed Journals of Other Institutions)

Synthesis and antinociceptive activity of some 1-phenyl-2-(2-benzothiazolinone-3-yl) ethanones and their reduced derivatives

Cakir B., Dogruer S. , Yesilada E. , ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, vol.14, no.2, pp.92-98, 1997 (Refereed Journals of Other Institutions)

Synthesis and antinociceptive activity of some 6-benzoyl-2(3H)-benzothiazolone derivatives

Cakir B., Dogruer S. , ÜNLÜ S., Yesilada E. , ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, vol.14, no.2, pp.103-109, 1997 (Refereed Journals of Other Institutions)

Antinociceptive activity of 3-aminoalkyl-2(3H)-benzothiazolone derivatives

Cakir B., Dogruer S. , ÜNLÜ S., ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, vol.14, no.1, pp.25-30, 1997 (Refereed Journals of Other Institutions)

Refereed Congress / Symposium Publications in Proceedings

SYNTHESIS OF SOME NEW 2-PHENOXYACETAMIDE AND 3-PHENOXYPROPANAMIDE DERIVATIVES AND EVALUATION OF THEIRCHOLINESTERASE INHIBITOR ACTIVITIES

Shakila S., Kılıç B. , Aksakal F., Doğruer D. S.

13th International Symposium on Pharmaceutical Sciences (ISOPS), Ankara, Turkey, 22 June 2021

Synthesis and antimicrobial activity of some new 3-[[1(2H)-phthalazinon-2-yl]methyl/ethyl]-4-aryl-1,2,4-triazole-5-thiones

ADAK S., DOĞRUER D. S. , ÖNKOL T. , UZUN L., ÖZKAN S., ŞAHİN M. F.

XIXth International Symposium on Medicinal Chemistry, 29 August 2006 - 02 September 2020

Design, Synthesis And Investigation Of New Diphenyl Substituted Pyridazinone Derivatives As Both Cholinesterase And Aβ-Aggregation Inhibitors

ERDOĞAN M., KILIÇ B. , GÜLCAN H. O. , AKSAKAL F., DOĞRUER D. S.

54TH INTERNATIONAL CONFERENCE ON MEDICINAL CHEMISTRY (RICT2018), Strasbourg, France, 4 - 06 July 2018

Synthesis Of New Benzothiazolone Derivatives And Evaluation Of Their Effects On Cholinesterase Enzymes

ERDOĞAN M., KILIÇ B. , DOĞRUER D. S.

2nd International Gazi Pharma Symposium Series (gpss2017), 11 - 13 October 2017

Synthesis Of Some Pyridazine Derivatives, Investigation Of Their In Vitro Acetylcholinesterase And Butyrylcholinesterase Inhibitory Activities

KILIÇ B. , GÜLCAN H. O. , AKSAKAL F., DOĞRUER D. S.

2nd International Gazi Pharma Symposium Series (GPSS2017), 11 - 13 October 2017

Synthesis Of Some New Benzothiazolone Derivatives And Investigation Of Their Cholinesterase Inhibitor Activities

DOĞRUER D. S. , ERDOĞAN M., KILIÇ B.

The 10th Joint Meeting On Medicinal Chemistry 2017 (jmmc2017), 25 - 28 June 2017

Synthesis Of Some New Benzoxazolone Derivatives And Evaluation Of Their Cholinesterase Inhibitor Activities

ERDOĞAN M., KILIÇ B. , DOĞRUER D. S.

The 10th Joint Meeting On Medicinal Chemistry 2017 (jmmc2017), 25 - 28 June 2017

Synthesis of Some New 5,6-Diphenyl Pyridazinone Derivatives and Invastigation Of Their Acetylcholinesterase Butyrylholinesterase

ERDOĞAN M., KILIÇ B. , DOĞRUER D. S.

Rencontres Internationales de Chimie Thérapeutique (RICT 2016), 6 - 08 July 2016

Design and Synthesis of Some New Benzoxazolone Derivatives for Cholinesterase Inhibitiıon

DOĞRUER D. S. , ERDOĞAN M., KILIÇ B.

Rencontres Internationales de Chimie Thérapeutique (RICT 2016), Caen, France, 6 - 08 July 2016

Development of Some New Pyridazine Derivatives for Cholinesterase Inhibitiıon

KILIÇ B. , DOĞRUER D. S.

Rencontres Internationales de Chimie Thérapeutique (RICT 2016), 6 - 08 July 2016

Bazı Yeni 1(2H)-Fitalazinon Türevlerinin Sentezi Ve Biyolojik Aktivitelerinin İncelenmesi

YALÇIN M., KILIÇ B. , DİMOGLO A., DOĞRUER D. S.

Türk Farmasötik ve Medisinal Kimya Derneği 4. Ulusal Farmasötik Kimya Kongresi, Girne, Cyprus (Kktc), 29 April - 01 May 2016

Synthesis of Some New 1(2H)-Phthalazinone Derivatives and Evaluation of Their Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities

DOĞRUER D. S. , KILIÇ B. , MERTCAN Y., DİMOGLO A.

1st International Gazi Pharma Symposium Series, Antalya, Turkey, 12 - 15 November 2015, pp.187

Synthesis of Some New 4,5-Diphenyl 3-(2H) Pyridazinone Derivatives and Evaluation of Their Inhibitory Activities on Acetylcholinesterase Butyrylcholinesterase Enzymes

KILIÇ B. , DOĞRUER D. S.

1st International Gazi Pharma Symposium Series, Antalya, Turkey, 12 - 15 November 2015, pp.189

Synthesis of Some New 4,6-Diphenyl 3(2H)-pyridazinone Derivatives and Evaluation of Their Inhibitory Activities on Acetylcholinesterase Butyrylcholinesterase Enzymes

KILIÇ B. , DOĞRUER D. S.

10th AFMC International Medicinal Chemistry Symposium, JEJU, South Korea, 18 - 21 October 2015, pp.204

Synthesis of Some 3(2H)-Pyridazinone and 1(2H)-Phthalazinone Derivatives Incorporating Aminothiazole Moiety and Investigation of Their Antioxidant, Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities.

DOĞRUER D. S. , YAMALI C., KILIÇ B. , OLĞAÇ S. , ŞÜKÜROĞLU M. K.

XXIII International Symposium on Medicinal Chemistry (EFMC-ISMC2014), Lizbon, Portugal, 7 - 11 September 2014

Synthesis of 6-(substituted urea/thiourea)-3-methyl-2-oxo-3H-benzoxazole derivatives and investigation of their antibacterial and antifungal activities

DOĞRUER D. S. , GÜLKOK Y., ÖZGEN S., KAYNAK ONURDAĞ F.

4th International Meeting on Medicinal And Pharmaceutical Chemistry (IMMPC-4) And 6th International Symposium on Pharmaceutical Chemistry (ISPC-6), Ankara, Turkey, 30 September - 02 October 2010

Bazı 6-(Tiyazol-4-il)-2-okso-3H-Benzoksazol türevlerinin Sentezi ve Siklooksijenaz İnhibitör Etkileri Üzerinde Çalışmalar

ÇANKARA PİROL Ş., ÜNLÜ S., DOĞRUER D. S. , ÖNKOL T. , ŞAHİN M. F.

2.Ulusal Farmasötik Kimya Kongresi, Mersin, Turkey, 13 - 15 November 2009

Bazı 6-(Sübstitüe tiyazol-4-il)-2-okso-3H-Benzoksazol türevlerinin Sentezi ve COX İnhibitör Aktivitelerinin Belirlenmesi Üzerinde Çalışma

URLU Ş., ÜNLÜ S., ÖNKOL T. , DOĞRUER D. S. , ŞAHİN M. F.

2.Ulusal Farmasötik Kimya Kongresi, Mersin, Turkey, 13 - 15 November 2009

Synthesis of Some Benzothiazolone Derivatives Carrying Urea and Thiourea Moieties

ÜNAL A., DOĞRUER D. S. , ÖNKOL T.

1st Turkish - Russian Joint Meeting on Organic and Medicinal Chemistry, Antalya, Turkey, 14 - 17 October 2009

Synthesis of Some Pyridazine Derivatives Carrying Urea, Thiourea And Sulfonamide Moieties And Their Antimicrobial Activity

DOĞRUER D. S. , URLU Ş., ÖNKOL T. , ÖZÇELİK B. , ŞAHİN M. F.

1st Turkish - Russian Joint Meeting on Organic and Medicinal Chemistry, Antalya, Turkey, 14 - 17 October 2009

Synthesis and Evaluation of Some New 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives as Antimicrobial Agents

ÖNKOL T. , DOĞRUER D. S. , ÖZÇELİK B. , ŞAHİN M. F.

1st Turkish - Russian Joint Meeting on Organic and Medicinal Chemistry, Antalya, Turkey, 14 - 17 October 2009

Synthesis, antimicrobial and antimycobacterial activities of some arylsulfonylhydrazide derivatives

DOĞRUER D. S. , ÖNKOL T. , ÖZKAN S., ÖZGEN S., ŞAHİN M. F.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Turkey, 16 - 21 October 2007

Synthesis of some [5-chloro-6-[2-(substitute phenyl)-1,3-thiazole-4-yl]-2-oxo-3H-benzothiazole-3-yl] acetic acid derivatives as potential dual inhibitors of COX-2 and thromboxane synthase

ADAK S., DOĞRUER D. S. , ÜNLÜ S.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Turkey, 16 - 21 October 2007

Studies on some 3(2H)-pyridazinone derivatives as potential antimicrobial and antimycobacterial agents

DOĞRUER D. S. , ÖNKOL T. , ÖZKAN S., ÖZGEN S., ŞAHİN M. F.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Turkey, 16 - 21 October 2007

Synthesis of some 5-chloro-6-(thiazol-4-yl)-2-oxo-3H-benzothiazole derivatives as potential COX-2 inhibitors

ADAK S., DOĞRUER D. S. , ÜNLÜ S.

International Symposium on Drug Research and Development, Antalya, Turkey, 17 - 20 May 2007

Synthesis and antimicrobial activity of some new 2-[[1(2H)-phthalazinon-2-yl]methyl/ethyl]-5-arylamino-1,3,4-thiadiazoles

UZUN L., ÖNKOL T. , DOĞRUER D. S. , ADAK S., ŞAHİN M. F.

XIXth International Symposium on Medicinal Chemistry, İstanbul, Turkey, 29 August - 02 September 2006

Synthesis of 2-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]acetmide and 3-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]propanamide Derivatives as analgesic and anti-inflammatory agents

DOĞRUER D. S. , ÜNLÜ S., AKKOL E. , BANOĞLU E. , ŞAHİN M. F.

XIXth International Symposium on Medicinal Chemistry, İstanbul, Turkey, 29 August - 02 September 2006

The In Vitro Hepatic Metabolism of 1-Phenyl-2-(2-Benzothiazolinone-3-yl)ethanone and ()-1-Phenyl-2-(2-Benzothiazolinone-3-yl)ethanol

ÜLGEN M., YILMAZ F., DOĞRUER D. S. , ÇAKIR B., ŞAHİN M. F.

16th European Workshop on Drug Metabolism, Copenhagen, Denmark, 21 - 26 June 1998

3-(Benzoylmethyl)Benzothiazole-2-one Derivatives: Synthesis and Antinociceptive Activity

ÇAKIR B., DOĞRUER D. S. , YEŞİLADA E., ŞAHİN M. F.

5th International Symposium on Pharmaceutical Sciences, Ankara, Turkey, 24 - 27 June 1997

Synthesis and Analgesic Activity of Some 6-Benzoyl-2(3H)-Benzothiazolone Derivatives

ÇAKIR B., DOĞRUER D. S. , ÜNLÜ S., YEŞİLADA E., ŞAHİN M. F.

XI. Ulusal Kimya Kongresi, Van, Turkey, 16 - 20 June 1997

Publications & Works

Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes

Articles Published in Other Journals

Refereed Congress / Symposium Publications in Proceedings