Prof.Dr. DENİZ SONGÜL DOĞRUER

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Design, synthesis and biological evaluation of new benzoxazolone/benzothiazolone derivatives as multi-target agents against Alzheimer's disease

Erdogan M., Kılıç B. , Sagkan R. I. , Aksakal F., Ercetin T., Gulcan H. O. , et al.

European Journal of Medicinal Chemistry, cilt.212, 2021 (SCI Expanded İndekslerine Giren Dergi)

Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and A beta-Aggregation Inhibitors

Kılıç B. , Erdogan M., Gulcan H. O. , Aksakarl F., Oruklu N. , Bağrıaçık E. Ü. , et al.

MEDICINAL CHEMISTRY, cilt.15, sa.1, ss.59-76, 2019 (SCI İndekslerine Giren Dergi)

Design and synthesis of some new carboxamide and propanamide derivatives bearing phenylpyridazine as a core ring and the investigation of their inhibitory potential on in-vitro acetylcholinesterase and butyrylcholinesterase

Kılıç B. , Gulcan H. O. , Aksakal F., Ercetin T., Oruklu N. , Bagriacik E. U. , et al.

BIOORGANIC CHEMISTRY, cilt.79, ss.235-249, 2018 (SCI İndekslerine Giren Dergi)

Synthesis of Some New 1(2H)-Phthalazinone Derivatives and Evaluation of Their Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities

KILIÇ B. , Gulcan H. O. , Yalcin M., Aksakal F., Dimoglo A., Sahin M. F. , et al.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.14, sa.2, ss.159-166, 2017 (SCI İndekslerine Giren Dergi)

Synthesis of some 3(2H)-pyridazinone and 1(2H)-phthalazinone derivatives incorporating aminothiazole moiety and investigation of their antioxidant, acetylcholinesterase, and butyrylcholinesterase inhibitory activities

Yamali C., Gulcan H. O. , Kahya B. , Cobanoglu S., ŞÜKÜROĞLU M. K. , DOĞRUER D. S.

MEDICINAL CHEMISTRY RESEARCH, cilt.24, sa.3, ss.1210-1217, 2015 (SCI İndekslerine Giren Dergi)

Studies on the synthesis of 3-methyl-6-(substituted-urea/-thiourea)-2(3H)-benzothiazolone derivatives and antimicrobial activities

Unal A. S. , KAYNAK ONURDAĞ F., Ozgen S., DOĞRUER D. S. , ÖNKOL T.

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, cilt.54, sa.2, ss.253-259, 2015 (SCI İndekslerine Giren Dergi)

Synthesis of Some New 3(2H)-Pyridazinone Derivatives and Evaluation of their Analgesic-anti-inflammatory and Antimicrobial Activities

Sukuroglu M. K. , Yamali C., Tiryaki D., Onurdag F. K. , AKKOL E. , DOĞRUER D. S.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.10, sa.6, ss.507-514, 2013 (SCI İndekslerine Giren Dergi)

Synthesis of some new 2,6-disubstituted-3(2H)-pyridazinone derivatives and investigation of their analgesic, anti-inflammatory and antimicrobial activities

Tiryaki D., Sukuroglu M. K. , DOĞRUER D. S. , AKKOL E. , Ozgen S., Sahin M. F.

MEDICINAL CHEMISTRY RESEARCH, cilt.22, sa.6, ss.2553-2560, 2013 (SCI İndekslerine Giren Dergi)

1-[4-(4-Chlorophenyl)piperazin-1-yl]-3-(6-oxo-3,4-diphenyl-1, 6-dihydropyridazin-1-yl)propan-1-one

Aydn A., AKKURT M., DOĞRUER D. S. , Büyükgüngör O.

Acta Crystallographica Section E: Structure Reports Online, cilt.68, sa.9, 2012 (SCI Expanded İndekslerine Giren Dergi)

Synthesis of some new urea and thiourea derivatives and evaluation of their antimicrobial activities

Gulkok Y., Bicer T., Onurdag F. K. , Ozgen S., Sahin M. F. , DOĞRUER D. S.

TURKISH JOURNAL OF CHEMISTRY, cilt.36, sa.2, ss.279-291, 2012 (SCI İndekslerine Giren Dergi)

Synthesis of some pyridazine derivatives carrying urea, thiourea, and sulfonamide moieties and their antimicrobial activity

Doğruer D. S. , Urlu S., Önkol T. , Özçelik B. , Sahin M. F.

TURKISH JOURNAL OF CHEMISTRY, cilt.34, sa.1, ss.57-65, 2010 (SCI İndekslerine Giren Dergi)

2-[2-(4-benzylpiperazin-1-ylcarbonyl)-ethyl]-5,6-diphenylpyridazin-3(2H)-one

AYDIN A., DOĞRUER D. S. , AKKURT M., BÜYÜKGÜNGÖR O.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, cilt.64, 2008 (SCI İndekslerine Giren Dergi)

Synthesis and antimicrobial activity of new 1,2,4-triazole and 1,3,4-thiadiazole derivatives

ÖNKOL T. , DOĞRUER D. S. , Uzun L., Adak S., Oezkan S., Sahin M. F.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, cilt.23, sa.2, ss.277-284, 2008 (SCI İndekslerine Giren Dergi)

Synthesis and antimicrobial activity of some 3(2H)-pyridazinone and 1(2H)-phthalazinone derivatives

DOĞRUER D. S. , ÖNKOL T. , Oezkan S., Oezgen S., Sahin M. F.

TURKISH JOURNAL OF CHEMISTRY, cilt.32, sa.4, ss.469-479, 2008 (SCI İndekslerine Giren Dergi)

2-(6-Oxo-3,4-diphenyl-1,6-dihydropyridazin-1-yl)acetic acid

Aydin A., DOĞRUER D. S. , Akkurt M., Bueyuekguengoer O.

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, cilt.63, 2007 (SCI İndekslerine Giren Dergi)

Synthesis of 2-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]acetamide and 3-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]propanamide derivatives as analgesic and anti-inflammatory agents

DOĞRUER D. S. , ÜNLÜ S. , Küpeli E., Banogǧlu E., ŞAHİN M. G.

Turkish Journal of Pharmaceutical Sciences, cilt.4, sa.2, ss.57-70, 2007 (SCI Expanded İndekslerine Giren Dergi)

Synthesis of new 2-[1(2H)-phthalazinon-2-yl]-acetamide and 3-[1(2H)-phthalazinon-2-yl]-propanamide derivatives as antinociceptive and anti-inflammatory agents

DOĞRUER D. S. , Kupeli E., Yesilada E., Sahin M.

ARCHIV DER PHARMAZIE, cilt.337, sa.6, ss.303-310, 2004 (SCI İndekslerine Giren Dergi)

3-(4-Aminobutyn-1-y1)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors

DOĞRUER D. S. , Lee M., Dukat M., Damaj I., Martin B., Glennon R.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, cilt.14, sa.2, ss.523-526, 2004 (SCI İndekslerine Giren Dergi)

Synthesis and analgesic and anti-inflammatory activity of new pyridazinones

DOĞRUER D. S. , Sahin M., Kupeli E., Yesilada E.

TURKISH JOURNAL OF CHEMISTRY, cilt.27, sa.6, ss.727-738, 2003 (SCI İndekslerine Giren Dergi)

Synthesis and antinociceptive activity of 6-substituted-3-pyridazinone derivatives

Gokce M., DOĞRUER D. S. , Sahin M.

FARMACO, cilt.56, sa.3, ss.233-237, 2001 (SCI İndekslerine Giren Dergi)

Synthesis and antinociceptive activity of (5-chloro-2-benzothiazolinon-3-yl)acetamide derivatives

Onkol T., DOĞRUER D. S. , Ito S., Sahin M.

ARCHIV DER PHARMAZIE, cilt.333, sa.10, ss.337-340, 2000 (SCI İndekslerine Giren Dergi)

Crystal structure of 1-[2-[6-(4-methoxyphenyl)-3(2H)-pyridazinone-2-yl]acetyl]-4-(2-pyridyl)piperazine

Ingec Ş. , Soylu H., Kendi E., DOĞRUER D. S. , Sahin M.

ANALYTICAL SCIENCES, cilt.16, sa.6, ss.669-670, 2000 (SCI İndekslerine Giren Dergi)

Studies on some 3(2H)-pyridazinone derivatives with antinociceptive activity

DOĞRUER D. S. , Sahin M., Unlu S., Ito S.

ARCHIV DER PHARMAZIE, cilt.333, sa.4, ss.79-86, 2000 (SCI İndekslerine Giren Dergi)

Synthesis and antinociceptive activity of some 3-substituted benzothiazolone derivatives

Cakir B., Ulucay A., DOĞRUER D. S. , Isimer A., Sahin M.

FARMACO, cilt.54, ss.846-851, 1999 (SCI İndekslerine Giren Dergi)

Synthesis and antinociceptive activity of (1-benzyl-2(3H)-benzimidazolon-3-yl) acetic acid derivatives

Nacak S. , DOĞRUER D. S. , Sahin M.

FARMACO, cilt.54, ss.768-772, 1999 (SCI İndekslerine Giren Dergi)

The in vitro effects of new non-steroidal antiinflammatory compounds on antioxidant system of human erythrocytes

Orhan H., DOĞRUER D. S. , Cakir B., Sahin G., Sahin M.

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, cilt.51, ss.397-402, 1999 (SCI İndekslerine Giren Dergi)

The in vitro hepatic metabolism of 1-phenyl-2-(2-benzothiazolinone-3-yl)ethanone and their reduced derivatives

Yilmaz F., Ulgen M., DOĞRUER D. S. , Cakir B., Sahin M.

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, cilt.51, ss.442-445, 1999 (SCI İndekslerine Giren Dergi)

Anti-nociceptive and anti-inflammatory activity of some (2-benzoxazolone-3-yl and 2-benzothiazolone-3-yl)acetic acid derivatives

Dogruer D. S. , Unlu S., Sahin M., Yesilada E.

Farmaco, cilt.53, sa.1, ss.80-84, 1999 (SCI Expanded İndekslerine Giren Dergi)

N-(2-Pyridinyl)-2-[2(3H)-benzazolone-3-YL]acetamides: Synthesis, antinociceptive and anti-inflammatory activity

DOĞRUER D. S. , Unlu S., Yesilada E., Sahin M.

FARMACO, cilt.52, sa.12, ss.745-750, 1997 (SCI İndekslerine Giren Dergi)

Diğer Dergilerde Yayınlanan Makaleler

6-Substituted-2-benzothiazolinone derivatives, synthesis and analgesic activity

ÖNKOL T. , Dogruer S. , ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.16, sa.1, ss.25-31, 1999 (Diğer Kurumların Hakemli Dergileri)

Synthesis and antinociceptive activity of some 1-phenyl-2-(2-benzothiazolinone-3-yl) ethanones and their reduced derivatives

Cakir B., Dogruer S. , Yesilada E. , ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.14, sa.2, ss.92-98, 1997 (Diğer Kurumların Hakemli Dergileri)

Synthesis and antinociceptive activity of some 6-benzoyl-2(3H)-benzothiazolone derivatives

Cakir B., Dogruer S. , ÜNLÜ S., Yesilada E. , ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.14, sa.2, ss.103-109, 1997 (Diğer Kurumların Hakemli Dergileri)

Antinociceptive activity of 3-aminoalkyl-2(3H)-benzothiazolone derivatives

Cakir B., Dogruer S. , ÜNLÜ S., ŞAHİN M. G.

Gazi Universitesi Eczacilik Fakultesi Dergisi, cilt.14, sa.1, ss.25-30, 1997 (Diğer Kurumların Hakemli Dergileri)

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar

Synthesis and antimicrobial activity of some new 3-[[1(2H)-phthalazinon-2-yl]methyl/ethyl]-4-aryl-1,2,4-triazole-5-thiones

ADAK S., DOĞRUER D. S. , ÖNKOL T. , UZUN L., ÖZKAN S., ŞAHİN M. F.

XIXth International Symposium on Medicinal Chemistry, 29 Ağustos 2006 - 02 Eylül 2020

Design, Synthesis And Investigation Of New Diphenyl Substituted Pyridazinone Derivatives As Both Cholinesterase And Aβ-Aggregation Inhibitors

ERDOĞAN M., KILIÇ B. , GÜLCAN H. O. , AKSAKAL F., DOĞRUER D. S.

54TH INTERNATIONAL CONFERENCE ON MEDICINAL CHEMISTRY (RICT2018), Strasbourg, Fransa, 4 - 06 Temmuz 2018

Synthesis Of New Benzothiazolone Derivatives And Evaluation Of Their Effects On Cholinesterase Enzymes

ERDOĞAN M., KILIÇ B. , DOĞRUER D. S.

2nd International Gazi Pharma Symposium Series (gpss2017), 11 - 13 Ekim 2017

Synthesis Of Some Pyridazine Derivatives, Investigation Of Their In Vitro Acetylcholinesterase And Butyrylcholinesterase Inhibitory Activities

KILIÇ B. , GÜLCAN H. O. , AKSAKAL F., DOĞRUER D. S.

2nd International Gazi Pharma Symposium Series (GPSS2017), 11 - 13 Ekim 2017

Synthesis Of Some New Benzothiazolone Derivatives And Investigation Of Their Cholinesterase Inhibitor Activities

DOĞRUER D. S. , ERDOĞAN M., KILIÇ B.

The 10th Joint Meeting On Medicinal Chemistry 2017 (jmmc2017), 25 - 28 Haziran 2017

Synthesis Of Some New Benzoxazolone Derivatives And Evaluation Of Their Cholinesterase Inhibitor Activities

ERDOĞAN M., KILIÇ B. , DOĞRUER D. S.

The 10th Joint Meeting On Medicinal Chemistry 2017 (jmmc2017), 25 - 28 Haziran 2017

Design and Synthesis of Some New Benzoxazolone Derivatives for Cholinesterase Inhibitiıon

DOĞRUER D. S. , ERDOĞAN M., KILIÇ B.

Rencontres Internationales de Chimie Thérapeutique (RICT 2016), Caen, Fransa, 6 - 08 Temmuz 2016

Development of Some New Pyridazine Derivatives for Cholinesterase Inhibitiıon

KILIÇ B. , DOĞRUER D. S.

Rencontres Internationales de Chimie Thérapeutique (RICT 2016), 6 - 08 Temmuz 2016

Synthesis of Some New 5,6-Diphenyl Pyridazinone Derivatives and Invastigation Of Their Acetylcholinesterase Butyrylholinesterase

ERDOĞAN M., KILIÇ B. , DOĞRUER D. S.

Rencontres Internationales de Chimie Thérapeutique (RICT 2016), 6 - 08 Temmuz 2016

Bazı Yeni 1(2H)-Fitalazinon Türevlerinin Sentezi Ve Biyolojik Aktivitelerinin İncelenmesi

YALÇIN M., KILIÇ B. , DİMOGLO A., DOĞRUER D. S.

Türk Farmasötik ve Medisinal Kimya Derneği 4. Ulusal Farmasötik Kimya Kongresi, Girne, Kıbrıs (Kktc), 29 Nisan - 01 Mayıs 2016

Synthesis of Some New 4,5-Diphenyl 3-(2H) Pyridazinone Derivatives and Evaluation of Their Inhibitory Activities on Acetylcholinesterase Butyrylcholinesterase Enzymes

KILIÇ B. , DOĞRUER D. S.

1st International Gazi Pharma Symposium Series, Antalya, Türkiye, 12 - 15 Kasım 2015, ss.189

Synthesis of Some New 1(2H)-Phthalazinone Derivatives and Evaluation of Their Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities

DOĞRUER D. S. , KILIÇ B. , MERTCAN Y., DİMOGLO A.

1st International Gazi Pharma Symposium Series, Antalya, Türkiye, 12 - 15 Kasım 2015, ss.187

Synthesis of Some New 4,6-Diphenyl 3(2H)-pyridazinone Derivatives and Evaluation of Their Inhibitory Activities on Acetylcholinesterase Butyrylcholinesterase Enzymes

KILIÇ B. , DOĞRUER D. S.

10th AFMC International Medicinal Chemistry Symposium, JEJU, Güney Kore, 18 - 21 Ekim 2015, ss.204

Synthesis of Some 3(2H)-Pyridazinone and 1(2H)-Phthalazinone Derivatives Incorporating Aminothiazole Moiety and Investigation of Their Antioxidant, Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities.

DOĞRUER D. S. , YAMALI C., KILIÇ B. , OLĞAÇ S. , ŞÜKÜROĞLU M. K.

XXIII International Symposium on Medicinal Chemistry (EFMC-ISMC2014), Lizbon, Portekiz, 7 - 11 Eylül 2014

Synthesis of 6-(substituted urea/thiourea)-3-methyl-2-oxo-3H-benzoxazole derivatives and investigation of their antibacterial and antifungal activities

DOĞRUER D. S. , GÜLKOK Y., ÖZGEN S., KAYNAK ONURDAĞ F.

4th International Meeting on Medicinal And Pharmaceutical Chemistry (IMMPC-4) And 6th International Symposium on Pharmaceutical Chemistry (ISPC-6), Ankara, Türkiye, 30 Eylül - 02 Ekim 2010

Bazı 6-(Sübstitüe tiyazol-4-il)-2-okso-3H-Benzoksazol türevlerinin Sentezi ve COX İnhibitör Aktivitelerinin Belirlenmesi Üzerinde Çalışma

URLU Ş., ÜNLÜ S., ÖNKOL T. , DOĞRUER D. S. , ŞAHİN M. F.

2.Ulusal Farmasötik Kimya Kongresi, Mersin, Türkiye, 13 - 15 Kasım 2009

Bazı 6-(Tiyazol-4-il)-2-okso-3H-Benzoksazol türevlerinin Sentezi ve Siklooksijenaz İnhibitör Etkileri Üzerinde Çalışmalar

ÇANKARA PİROL Ş., ÜNLÜ S., DOĞRUER D. S. , ÖNKOL T. , ŞAHİN M. F.

2.Ulusal Farmasötik Kimya Kongresi, Mersin, Türkiye, 13 - 15 Kasım 2009

Synthesis of Some Pyridazine Derivatives Carrying Urea, Thiourea And Sulfonamide Moieties And Their Antimicrobial Activity

DOĞRUER D. S. , URLU Ş., ÖNKOL T. , ÖZÇELİK B. , ŞAHİN M. F.

1st Turkish - Russian Joint Meeting on Organic and Medicinal Chemistry, Antalya, Türkiye, 14 - 17 Ekim 2009

Synthesis of Some Benzothiazolone Derivatives Carrying Urea and Thiourea Moieties

ÜNAL A., DOĞRUER D. S. , ÖNKOL T.

1st Turkish - Russian Joint Meeting on Organic and Medicinal Chemistry, Antalya, Türkiye, 14 - 17 Ekim 2009

Synthesis and Evaluation of Some New 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives as Antimicrobial Agents

ÖNKOL T. , DOĞRUER D. S. , ÖZÇELİK B. , ŞAHİN M. F.

1st Turkish - Russian Joint Meeting on Organic and Medicinal Chemistry, Antalya, Türkiye, 14 - 17 Ekim 2009

Synthesis, antimicrobial and antimycobacterial activities of some arylsulfonylhydrazide derivatives

DOĞRUER D. S. , ÖNKOL T. , ÖZKAN S., ÖZGEN S., ŞAHİN M. F.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Türkiye, 16 - 21 Ekim 2007

Synthesis of some [5-chloro-6-[2-(substitute phenyl)-1,3-thiazole-4-yl]-2-oxo-3H-benzothiazole-3-yl] acetic acid derivatives as potential dual inhibitors of COX-2 and thromboxane synthase

ADAK S., DOĞRUER D. S. , ÜNLÜ S.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Türkiye, 16 - 21 Ekim 2007

Studies on some 3(2H)-pyridazinone derivatives as potential antimicrobial and antimycobacterial agents

DOĞRUER D. S. , ÖNKOL T. , ÖZKAN S., ÖZGEN S., ŞAHİN M. F.

3rd International Meeting on Medicinal and Pharmaceutical Chemistry, Antalya, Türkiye, 16 - 21 Ekim 2007

Synthesis of some 5-chloro-6-(thiazol-4-yl)-2-oxo-3H-benzothiazole derivatives as potential COX-2 inhibitors

ADAK S., DOĞRUER D. S. , ÜNLÜ S.

International Symposium on Drug Research and Development, Antalya, Türkiye, 17 - 20 Mayıs 2007

Synthesis and antimicrobial activity of some new 2-[[1(2H)-phthalazinon-2-yl]methyl/ethyl]-5-arylamino-1,3,4-thiadiazoles

UZUN L., ÖNKOL T. , DOĞRUER D. S. , ADAK S., ŞAHİN M. F.

XIXth International Symposium on Medicinal Chemistry, İstanbul, Türkiye, 29 Ağustos - 02 Eylül 2006

Synthesis of 2-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]acetmide and 3-[5,6-diphenyl-3(2H)-pyridazinone-2-yl]propanamide Derivatives as analgesic and anti-inflammatory agents

DOĞRUER D. S. , ÜNLÜ S., AKKOL E. , BANOĞLU E. , ŞAHİN M. F.

XIXth International Symposium on Medicinal Chemistry, İstanbul, Türkiye, 29 Ağustos - 02 Eylül 2006

The In Vitro Hepatic Metabolism of 1-Phenyl-2-(2-Benzothiazolinone-3-yl)ethanone and ()-1-Phenyl-2-(2-Benzothiazolinone-3-yl)ethanol

ÜLGEN M., YILMAZ F., DOĞRUER D. S. , ÇAKIR B., ŞAHİN M. F.

16th European Workshop on Drug Metabolism, Copenhagen, Danimarka, 21 - 26 Haziran 1998

Yayınlar & Eserler

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Diğer Dergilerde Yayınlanan Makaleler

Hakemli Kongre / Sempozyum Bildiri Kitaplarında Yer Alan Yayınlar